We are analyzing https://link.springer.com/article/10.1186/s40168-017-0296-0.

Title:
(Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease | Microbiome
Description:
Chronic inflammation represents one of the most consistent biologic features of aging. However, the precise etiology of persistent low-grade increases in inflammation remains unclear. Recent evidence suggests that the gut microbiome may play a key role in age-related inflammation. Indeed, several studies have indicated that older adults display an altered composition of the gut microbiota, and early evidence indicates that this dysbiosis is associated with the presence of several key circulating inflammatory analytes. The present review summarizes knowledge on age-related inflammation and discusses how potential relationships with gut dysbiosis may lead to novel treatment strategies in the future. “The pattern of disease is an expression of the response of man to his total environment (physical, biological, and social); this response is, therefore, determined by anything that affects man himself or his environment.” – Rene Dubos, 1961
Website Age:
28 years and 1 months (reg. 1997-05-29).

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Health & Fitness
Education
Science

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Keywords {🔍}

pubmed, article, google, scholar, cas, gut, inflammation, microbiota, microbiome, aging, agerelated, central, health, inflammatory, intestinal, disease, composition, immune, older, human, age, adults, diet, sci, chronic, dysbiosis, diseases, elderly, studies, study, exercise, function, med, potential, ageing, effects, data, risk, cell, probiotics, nutr, evidence, factors, conditions, responses, microbial, immunity, clin, role, systemic,

Topics {✒️}

short-chain fatty acids conventionally raised mice recent pubmed search persistent low-grade increases high-sugar “western” diet systemic pro-inflammatory cytokines diet-induced obese rat metabolite-sensing receptor gpr43 chronic low-grade inflammation long-term care facilities high-fat diet commonly hypothalamus-pituitary-adrenal il-6 pubmed search article download pdf reversed age-related microbial underlie age-related increases c-reactive protein levels age-related diseases grows gut dysbiosis—commonly defined long-term systemic consequences central risk factors defined gut-brain axis increased intestinal permeability age-related cognitive decline potential anti-inflammatory affect inflammatory bowel conditions antibiotic-treated elderly subjects pro-inflammatory cytokines gut micro-organisms compared de graaf aa pubmed citations privacy choices/manage cookies partially explain age-related lactobacillus delbrueckii subsp search term “aging high-saturated fat age-related diseases/disorders [5 driving age-related inflammation low-grade inflammation circulating inflammatory analytes irritable bowel syndrome high-fat diet increased cytokine production long-term care inflammatory cytokines interleukins hypothalamus-pituitary-adrenal creative commons license intestinal epithelial barrier article buford circulating plasma concentrations

Questions {❓}

A breakdown in communication?
Food: a new form of personalised (gut microbiome) medicine for chronic diseases?
Gut microbiota modification: another piece in the puzzle of the benefits of physical exercise in health?
Inflammation and cancer: how hot is the link?
What are the consequences of the disappearing human microbiota?

Schema {🗺️}

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