We are analyzing https://link.springer.com/article/10.1186/s13287-022-02835-x.

Title:
Adult stem cell sources for skeletal and smooth muscle tissue engineering | Stem Cell Research & Therapy
Description:
Introduction Tissue engineering is an innovative field with enormous developments in recent years. These advances are not only in the understanding of how stem cells can be isolated, cultured and manipulated but also in their potential for clinical applications. Thus, tissue engineering when applied to skeletal and smooth muscle cells is an area that bears high benefit for patients with muscular diseases or damage. Most of the recent research has been focused on use of adult stem cells. These cells have the ability to rejuvenate and repair damaged tissues and can be derived from different organs and tissue sources. Recently there are several different types of adult stem cells, which have the potential to function as a cell source for tissue engineering of skeletal and smooth muscles. However, to build neo‐tissues there are several challenges which have to be addressed, such as the selection of the most suitable stem cell type, isolation techniques, gaining control over its differentiation and proliferation process. Conclusion The usage of adult stem cells for muscle engineering applications is promising. Here, we summarize the status of research on the use of adult stem cells for cell transplantation in experimental animals and humans. In particular, the application of skeletal and smooth muscle engineering in pre-clinical and clinical trials will be discussed.
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Keywords {🔍}

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Topics {✒️}

percutaneous trans-coronary-venous transplantation adipose-derived stem-cell treatment cell seeded grafts urine-derived stem cells bone marrow-derived cells bone-marrow derived cells adipose-derived stem cells muscle-derived stem cells endometrial stem/progenitor cells muscle-specific transcription factors muscle-derived cell transplants adipose tissue-derived cells article download pdf myogenic lineage-specific markers cd45+/sca1− cells derived cd45+/sca1+ cells derived encapsulating bone-marrow mscs transforming growth factor-b1 transforming growth factor-beta1 muscle-derived cell injection single-arm clinical trial prp-derived fibrin microbeads mesenchymal stem cells human amniotic fluid human umbilical cord amniotic fluid derived adult stem cells purely qol questionnaire-based stem cell research single-cell transplantation study post-prostatectomy urinary incontinence viable satellite-cell pool pax7 + myod- cells return hematopoietic stem cells tissue-engineered autologous bladders regenerating skeletal muscle multipotent stem cells incontinence impact questionnaire urine derived cells human smooth muscle muscle isolated cd45+/sca1+ cd45+/sca1+ cells isolated valentin baumgartner adult skeletal muscle received transplanted kidneys dimensional synthetic composite adipose stem cells transurethral ultrasound-guided injections muscle stem cells muscle-derived cells

Questions {❓}

Myogenic precursor cell transplantation in pigs: a step towards a clinical use for muscle regeneration?
Oct-4-expressing cells in human amniotic fluid: a new source for stem cell research?
Phenotypic changes in cultured smooth muscle cells: limitation or opportunity for tissue engineering of hollow organs?

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