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LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Schema
  9. External Links
  10. Analytics And Tracking
  11. Libraries
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We are analyzing https://link.springer.com/article/10.1186/s13073-015-0240-5.

Title:
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression | Genome Medicine
Description:
Human cancer cell lines are an important resource for research and drug development. However, the available annotations of cell lines are sparse, incomplete, and distributed in multiple repositories. Re-analyzing publicly available raw RNA-Seq data, we determined the human leukocyte antigen (HLA) type and abundance, identified expressed viruses and calculated gene expression of 1,082 cancer cell lines. Using the determined HLA types, public databases of cell line mutations, and existing HLA binding prediction algorithms, we predicted antigenic mutations in each cell line. We integrated the results into a comprehensive knowledgebase. Using the Django web framework, we provide an interactive user interface with advanced search capabilities to find and explore cell lines and an application programming interface to extract cell line information. The portal is available at http://celllines.tron-mainz.de .
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {πŸ“š}

  • Telecommunications
  • Technology & Computing
  • Education

Content Management System {πŸ“}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {πŸ“ˆ}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

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How Does Link.springer.com Make Money? {πŸ’Έ}

We're unsure how the site profits.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Link.springer.com might have a hidden revenue stream, but it's not something we can detect.

Keywords {πŸ”}

cell, hla, line, cancer, pubmed, article, lines, data, type, expression, google, scholar, class, gene, information, human, search, rnaseq, cas, genome, virus, reads, neoepitope, central, interface, determined, mutations, binding, mutation, portal, predicted, access, boegel, catalog, fig, tclp, annotations, types, integrated, user, ccle, table, sequence, rpkm, typing, including, sebastian, antigen, expressed, viruses,

Topics {βœ’οΈ}

human leukocyte antigen cancer-specific peptide-hla complexes paired-end rna-seq samples viral-related human carcinogenesis 101Β nt paired-end sequencing 75Β nt paired-end sequencing class ii neo-epitopes accurate pan-specific prediction class ii neo-antigens article download pdf european genome-phenome archive neo-epitope prediction based raw rna-seq data human endogenous retrovirus including rna-seq datasets antigen presentation datasets rna-seq datasets analyzing rna-seq data uk/ega/datasets/egad00001000725 cancer-related virus infections virus-related hepatocellular carcinoma explore cell lines calculate gene-level expression rna-seq sequence reads processed rna-seq data class ii type human reference genome web-based user interface class ii types cell line origin cell line annotation selected cell line current cell line rna-seq analysis predicted neo-epitopes cell line information cell line mutations cell line annotations class ii genotypes johannes gutenberg-university mainz cell line primary national cancer institute privacy choices/manage cookies predicted hla class specific hla type neo-epitope candidates sequence alignment/map format rna-seq data targeted pcr amplification cell lines a375

Schema {πŸ—ΊοΈ}

WebPage:
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         description:Human cancer cell lines are an important resource for research and drug development. However, the available annotations of cell lines are sparse, incomplete, and distributed in multiple repositories. Re-analyzing publicly available raw RNA-Seq data, we determined the human leukocyte antigen (HLA) type and abundance, identified expressed viruses and calculated gene expression of 1,082 cancer cell lines. Using the determined HLA types, public databases of cell line mutations, and existing HLA binding prediction algorithms, we predicted antigenic mutations in each cell line. We integrated the results into a comprehensive knowledgebase. Using the Django web framework, we provide an interactive user interface with advanced search capabilities to find and explore cell lines and an application programming interface to extract cell line information. The portal is available at http://celllines.tron-mainz.de .
         datePublished:2015-11-20T00:00:00Z
         dateModified:2015-11-20T00:00:00Z
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            Human Leukocyte Antigen Class
            Human Leukocyte Antigen Allele
            Human Leukocyte Antigen Type
            Cancer Cell Line Encyclopedia
            Human Genetics
            Metabolomics
            Bioinformatics
            Medicine/Public Health
            general
            Cancer Research
            Systems Biology
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                        name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
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ScholarlyArticle:
      headline:TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression
      description:Human cancer cell lines are an important resource for research and drug development. However, the available annotations of cell lines are sparse, incomplete, and distributed in multiple repositories. Re-analyzing publicly available raw RNA-Seq data, we determined the human leukocyte antigen (HLA) type and abundance, identified expressed viruses and calculated gene expression of 1,082 cancer cell lines. Using the determined HLA types, public databases of cell line mutations, and existing HLA binding prediction algorithms, we predicted antigenic mutations in each cell line. We integrated the results into a comprehensive knowledgebase. Using the Django web framework, we provide an interactive user interface with advanced search capabilities to find and explore cell lines and an application programming interface to extract cell line information. The portal is available at http://celllines.tron-mainz.de .
      datePublished:2015-11-20T00:00:00Z
      dateModified:2015-11-20T00:00:00Z
      pageStart:1
      pageEnd:7
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         Human Leukocyte Antigen
         Human Leukocyte Antigen Class
         Human Leukocyte Antigen Allele
         Human Leukocyte Antigen Type
         Cancer Cell Line Encyclopedia
         Human Genetics
         Metabolomics
         Bioinformatics
         Medicine/Public Health
         general
         Cancer Research
         Systems Biology
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                  name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
                  address:
                     name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
                     type:PostalAddress
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                  name:Present address: European Molecular Biology Laboratory
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                     name:Present address: European Molecular Biology Laboratory, Heidelberg, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sebastian Boegel
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                  address:
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                  name:University Medical Center of the Johannes Gutenberg-University Mainz
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            name:Marius Byl
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                  address:
                     name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
                     type:PostalAddress
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            name:Sebastian Goerges
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                  address:
                     name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
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                  address:
                     name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
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            name:Martin Loewer
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                  address:
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                  address:
                     name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
                     type:PostalAddress
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                  name:University Medical Center of the Johannes Gutenberg-University Mainz
                  address:
                     name:University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
                     type:PostalAddress
                  type:Organization
                  name:Biopharmaceutical New Technologies (BioNTech) Corporation
                  address:
                     name:Biopharmaceutical New Technologies (BioNTech) Corporation, Mainz, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:John C. Castle
            affiliation:
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                  address:
                     name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
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Person:
      name:Jelle Scholtalbers
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            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
            name:Present address: European Molecular Biology Laboratory
            address:
               name:Present address: European Molecular Biology Laboratory, Heidelberg, Germany
               type:PostalAddress
            type:Organization
      name:Sebastian Boegel
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
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            name:University Medical Center of the Johannes Gutenberg-University Mainz
            address:
               name:University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Thomas Bukur
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
            name:University Medical Center of the Johannes Gutenberg-University Mainz
            address:
               name:University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Marius Byl
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Sebastian Goerges
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Patrick Sorn
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Martin Loewer
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:Ugur Sahin
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
            name:University Medical Center of the Johannes Gutenberg-University Mainz
            address:
               name:University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
               type:PostalAddress
            type:Organization
            name:Biopharmaceutical New Technologies (BioNTech) Corporation
            address:
               name:Biopharmaceutical New Technologies (BioNTech) Corporation, Mainz, Germany
               type:PostalAddress
            type:Organization
      name:John C. Castle
      affiliation:
            name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University
            address:
               name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
               type:PostalAddress
            type:Organization
            name:Present address: Agenus and 4-Antibody AG
            address:
               name:Present address: Agenus and 4-Antibody AG, Basel, Switzerland
               type:PostalAddress
            type:Organization
PostalAddress:
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:Present address: European Molecular Biology Laboratory, Heidelberg, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany
      name:Biopharmaceutical New Technologies (BioNTech) Corporation, Mainz, Germany
      name:TRON – Translational Oncology at the University Medical Center of Johannes Gutenberg University, Mainz, Germany
      name:Present address: Agenus and 4-Antibody AG, Basel, Switzerland

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