We are analyzing https://link.springer.com/article/10.1186/gb-2007-8-5-r82.

Title:
Exon arrays provide accurate assessments of gene expression | Genome Biology
Description:
We have developed a strategy for estimating gene expression on Affymetrix Exon arrays. The method includes a probe-specific background correction and a probe selection strategy in which a subset of probes with highly correlated intensities across multiple samples are chosen to summarize gene expression. Our results demonstrate that the proposed background model offers improvements over the default Affymetrix background correction and that Exon arrays may provide more accurate measurements of gene expression than traditional 3
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Keywords {🔍}

expression, exon, arrays, background, probes, gene, probe, array, model, article, pubmed, affymetrix, genes, tissue, mat, human, set, google, scholar, data, genelevel, correction, analysis, intensities, mouse, methods, full, selection, cas, figure, sage, sets, indices, core, calls, central, number, intensity, oligonucleotide, panel, correlation, positive, rate, accurate, signal, genome, strategy, microarray, index, values,

Topics {✒️}

𝑃 𝑀 𝑖 cross-species gene expression wing hung wong gene-level expression index gene-level expression indices estimating gene-level expression interrogate exon-level expression exon-level expression relative /support/technical/datasheets/exon_arraydesign_datasheet /support/technical/technotes/plier_technote /support/technical/whitepapers/exon_gene_signal_estimate_whitepaper /support/technical/whitepapers/exon_alt_transcript_analysis_whitepaper /support/technical/sample_data/exon_array_data gov/pub/homologene/] genebase article number r82 article download pdf estimate gene-level expression tissue-specific gene expression probe-specific background correction background-corrected probe intensities microarray-based expression monitoring human protein-encoding transcriptomes probe-specific error term cross-species comparisons model-based background adjustment dimensional transcriptome profiling perfect-match targets compared signed-rank call algorithms cross-species correlation gene expression index gene-level expression offer future improvements cross-species conservation specific gene targets gene expression indices accurate background correction tissue panel dataset estimating gene expression affymetrix genechip microarray gene signal estimates expression index computation construct gold-standard sets background-corrected intensity gene expression patterns privacy choices/manage cookies high-level analysis construct gold-standard expressed summarize gene expression related subjects calculating gene expression

Questions {❓}

Can this dramatic increase in coverage be exploited to improve quantitative estimation of gene-level expression?
Millenaar FF, Okyere J, May ST, van Zanten M, Voesenek LA, Peeters AJ: How to decide?

Schema {🗺️}

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            Bioinformatics
            Evolutionary Biology
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      headline:Exon arrays provide accurate assessments of gene expression
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         Probe Intensity
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         Microbial Genetics and Genomics
         Bioinformatics
         Evolutionary Biology
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