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Title:
CellProfiler: image analysis software for identifying and quantifying cell phenotypes | Genome Biology
Description:
Biologists can now prepare and image thousands of samples per day using automation, enabling chemical screens and functional genomics (for example, using RNA interference). Here we describe the first free, open-source system designed for flexible, high-throughput cell image analysis, CellProfiler. CellProfiler can address a variety of biological questions quantitatively, including standard assays (for example, cell count, size, per-cell protein levels) and complex morphological assays (for example, cell/organelle shape or subcellular patterns of DNA or protein staining).
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Keywords {🔍}
image, cell, analysis, cells, cellprofiler, google, scholar, article, data, pubmed, images, software, figure, file, additional, cas, content, features, modules, human, measurements, drosophila, dna, shape, cytometry, screening, size, types, algorithms, methods, rnai, measures, texture, screens, biological, cellular, including, identification, cellprofilers, highthroughput, assay, nuclei, samples, automated, intensity, nucleus, assays, protein, cycle, high,
Topics {✒️}
/c12567be0045acf1/contents-frame/fde18daae4583a5cc1256c3d004831ff] invitation probe cell proliferation/apoptosis/death image-based genome-wide screens net/posters/p12024-quality measures basic cell-culture methods jason moffat & david rnai genome-wide screening article number r100 complete open-source infrastructure systematic genome-wide screens high-throughput imaging technologies high-throughput rnai screening cell-count/object-count screen jason moffat tab-delimited spreadsheet format flow cytometry based imaging-based cellular assays article download pdf merck/csbi postdoctoral fellowship automated centrosome-duplication assay hsp90-dependent drug resistance high-throughput image set high-throughput biology laboratories high-throughput rna interference phospho-h3-negative cells phospho-histone h3 tend fluorescence-based image cytometer open-source system designed cytological profiles high throughput imaging real-world biological problems multiparameter single-cell data large-scale cell biology wild-type control cells author information authors open-source cellprofiler project wild-type drosophila nuclei wild-type human sample rnai living-cell microarrays cytoplasm-nucleus translocation assay single-cell western blots wild-type cells show cell-based drug discovery flow cytometry rna-interference induced samples human-scored image analysis high-throughput screens image cytometry reveals dose-response image set high-content screening
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headline:CellProfiler: image analysis software for identifying and quantifying cell phenotypes
description:Biologists can now prepare and image thousands of samples per day using automation, enabling chemical screens and functional genomics (for example, using RNA interference). Here we describe the first free, open-source system designed for flexible, high-throughput cell image analysis, CellProfiler. CellProfiler can address a variety of biological questions quantitatively, including standard assays (for example, cell count, size, per-cell protein levels) and complex morphological assays (for example, cell/organelle shape or subcellular patterns of DNA or protein staining).
datePublished:2006-10-31T00:00:00Z
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Additional Data File
Wortmannin
Image Cytometry
Kc167 Cell
Translocation Assay
Animal Genetics and Genomics
Human Genetics
Plant Genetics and Genomics
Microbial Genetics and Genomics
Bioinformatics
Evolutionary Biology
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headline:CellProfiler: image analysis software for identifying and quantifying cell phenotypes
description:Biologists can now prepare and image thousands of samples per day using automation, enabling chemical screens and functional genomics (for example, using RNA interference). Here we describe the first free, open-source system designed for flexible, high-throughput cell image analysis, CellProfiler. CellProfiler can address a variety of biological questions quantitatively, including standard assays (for example, cell count, size, per-cell protein levels) and complex morphological assays (for example, cell/organelle shape or subcellular patterns of DNA or protein staining).
datePublished:2006-10-31T00:00:00Z
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Additional Data File
Wortmannin
Image Cytometry
Kc167 Cell
Translocation Assay
Animal Genetics and Genomics
Human Genetics
Plant Genetics and Genomics
Microbial Genetics and Genomics
Bioinformatics
Evolutionary Biology
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