We are analyzing https://link.springer.com/article/10.1186/bcr2577.

Title:
Tumour-associated carbohydrate antigens in breast cancer | Breast Cancer Research
Description:
Glycosylation changes that occur in cancer often lead to the expression of tumour-associated carbohydrate antigens. In breast cancer, these antigens are usually associated with a poor prognosis and a reduced overall survival. Cellular models have shown the implication of these antigens in cell adhesion, migration, proliferation and tumour growth. The present review summarizes our current knowledge of glycosylation changes (structures, biosynthesis and occurrence) in breast cancer cell lines and primary tumours, and the consequences on disease progression and aggressiveness. The therapeutic strategies attempted to target tumour-associated carbohydrate antigens in breast cancer are also discussed.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Health & Fitness
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,642,828 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We find it hard to spot revenue streams.

Some websites aren't about earning revenue; they're built to connect communities or raise awareness. There are numerous motivations behind creating websites. This might be one of them. Link.springer.com might be cashing in, but we can't detect the method they're using.

Keywords {🔍}

cancer, breast, pubmed, google, scholar, expression, cas, article, cells, antigen, antigens, cell, human, patients, stn, res, carcinoma, gangliosides, figure, biosynthesis, tissues, type, carbohydrate, slex, tumour, metastasis, core, lewis, prognosis, expressed, shown, stgal, normal, synthase, involved, cancers, muc, lectin, glycosylation, survival, tumours, glycans, specific, fuct, delannoy, adhesion, lymph, biol, structures, high,

Topics {✒️}

n-acetyl-d-galactosamine-recognizing lectins neu5acα2-3galβ1-3galnacα-ser/thr soyasaponin-imodified invasive behavior glycosylation profile thomsen-friedenreich-related carbohydrate antigens author information authors betagalactoside-mediated homotypic aggregation invasive ductal carcinomas galβ1-3galnacα-ser/thr galβ1-3galnacα1-ser/thr oestrogen receptor-positive samples anti-idiotypic monoclonal antibody compare multi-antigenic responses philippe delannoy mucin-type o-glycosylation node-positive breast cancer paclitaxel combined-modality radioimmunotherapy neutral o-linked polylactosaminoglycans 90y-radiolabeled anti-lewis uptake muc1-tn peptide blood-group-related antigens oestrogen receptor-negative tumours van vliet sj abh/lewis-related antigens derivatives 9-o-acetyl-gd3 stn-positive proteins present tn-positive metastatic cells histo-blood group antigens author correspondence pathological tumor-node-metastasis macrophage galactose-type lectin mda-mb-231 cells anti-taca cancer vaccines common phenotypic change thomsen-friedenreich tumor antigen stn-positive proteins expressed profile interestingly anti-stn antibodies investigate t-antigen expression o-linked carbohydrate antigens sialyl-tn o-glycan circulating e-selectin concentrations artocarpus integrifolia agglutinin/jacalin n-glycolyl-gm3 elicited ganglioside-based vaccines carcinoma cell lines transfected cell lines human beta-galactoside alpha2 villeneuve d'ascq short o-glycans observed

Questions {❓}

Kawaguchi T, Takazawa H, Imai S, Morimoto J, Watanabe T, Kanno M, Igarashi S: Expression of Vicia villosa agglutinin (VVA)-binding glycoprotein in primary breast cancer cells in relation to lymphatic metastasis: is atypical MUC1 bearing Tn antigen a receptor of VVA?
Slovin SF, Ragupathi G, Fernandez C, Diani M, Jefferson MP, Wilton A, Kelly WK, Morris M, Solit D, Clausen H, Livingston P, Scher HI: A polyvalent vaccine for high-risk prostate patients: 'are more antigens better?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Tumour-associated carbohydrate antigens in breast cancer
         description:Glycosylation changes that occur in cancer often lead to the expression of tumour-associated carbohydrate antigens. In breast cancer, these antigens are usually associated with a poor prognosis and a reduced overall survival. Cellular models have shown the implication of these antigens in cell adhesion, migration, proliferation and tumour growth. The present review summarizes our current knowledge of glycosylation changes (structures, biosynthesis and occurrence) in breast cancer cell lines and primary tumours, and the consequences on disease progression and aggressiveness. The therapeutic strategies attempted to target tumour-associated carbohydrate antigens in breast cancer are also discussed.
         datePublished:2010-06-08T00:00:00Z
         dateModified:2010-06-08T00:00:00Z
         pageStart:1
         pageEnd:13
         sameAs:https://doi.org/10.1186/bcr2577
         keywords:
            Breast Cancer
            sLea
            Invasive Ductal Carcinoma
            Lewis Antigen
            Glycosylation Change
            Cancer Research
            Oncology
            Surgical Oncology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig1_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig2_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig3_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig4_HTML.jpg
         isPartOf:
            name:Breast Cancer Research
            issn:
               1465-542X
            volumeNumber:12
            type:
               Periodical
               PublicationVolume
         publisher:
            name:BioMed Central
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Aurélie Cazet
               affiliation:
                     name:University of Scienaces and Technologies of Lille
                     address:
                        name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
                        type:PostalAddress
                     type:Organization
                     name:Université Lille Nord de France
                     address:
                        name:Université Lille Nord de France, Lille, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sylvain Julien
               affiliation:
                     name:King's College London
                     address:
                        name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Marie Bobowski
               affiliation:
                     name:University of Scienaces and Technologies of Lille
                     address:
                        name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
                        type:PostalAddress
                     type:Organization
                     name:Université Lille Nord de France
                     address:
                        name:Université Lille Nord de France, Lille, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Joy Burchell
               affiliation:
                     name:King's College London
                     address:
                        name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Philippe Delannoy
               affiliation:
                     name:University of Scienaces and Technologies of Lille
                     address:
                        name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
                        type:PostalAddress
                     type:Organization
                     name:Université Lille Nord de France
                     address:
                        name:Université Lille Nord de France, Lille, France
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Tumour-associated carbohydrate antigens in breast cancer
      description:Glycosylation changes that occur in cancer often lead to the expression of tumour-associated carbohydrate antigens. In breast cancer, these antigens are usually associated with a poor prognosis and a reduced overall survival. Cellular models have shown the implication of these antigens in cell adhesion, migration, proliferation and tumour growth. The present review summarizes our current knowledge of glycosylation changes (structures, biosynthesis and occurrence) in breast cancer cell lines and primary tumours, and the consequences on disease progression and aggressiveness. The therapeutic strategies attempted to target tumour-associated carbohydrate antigens in breast cancer are also discussed.
      datePublished:2010-06-08T00:00:00Z
      dateModified:2010-06-08T00:00:00Z
      pageStart:1
      pageEnd:13
      sameAs:https://doi.org/10.1186/bcr2577
      keywords:
         Breast Cancer
         sLea
         Invasive Ductal Carcinoma
         Lewis Antigen
         Glycosylation Change
         Cancer Research
         Oncology
         Surgical Oncology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig1_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig2_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig3_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fbcr2577/MediaObjects/13058_2010_2538_Fig4_HTML.jpg
      isPartOf:
         name:Breast Cancer Research
         issn:
            1465-542X
         volumeNumber:12
         type:
            Periodical
            PublicationVolume
      publisher:
         name:BioMed Central
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Aurélie Cazet
            affiliation:
                  name:University of Scienaces and Technologies of Lille
                  address:
                     name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
                     type:PostalAddress
                  type:Organization
                  name:Université Lille Nord de France
                  address:
                     name:Université Lille Nord de France, Lille, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sylvain Julien
            affiliation:
                  name:King's College London
                  address:
                     name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marie Bobowski
            affiliation:
                  name:University of Scienaces and Technologies of Lille
                  address:
                     name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
                     type:PostalAddress
                  type:Organization
                  name:Université Lille Nord de France
                  address:
                     name:Université Lille Nord de France, Lille, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Joy Burchell
            affiliation:
                  name:King's College London
                  address:
                     name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Philippe Delannoy
            affiliation:
                  name:University of Scienaces and Technologies of Lille
                  address:
                     name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
                     type:PostalAddress
                  type:Organization
                  name:Université Lille Nord de France
                  address:
                     name:Université Lille Nord de France, Lille, France
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Breast Cancer Research
      issn:
         1465-542X
      volumeNumber:12
Organization:
      name:BioMed Central
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Scienaces and Technologies of Lille
      address:
         name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
         type:PostalAddress
      name:Université Lille Nord de France
      address:
         name:Université Lille Nord de France, Lille, France
         type:PostalAddress
      name:King's College London
      address:
         name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
         type:PostalAddress
      name:University of Scienaces and Technologies of Lille
      address:
         name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
         type:PostalAddress
      name:Université Lille Nord de France
      address:
         name:Université Lille Nord de France, Lille, France
         type:PostalAddress
      name:King's College London
      address:
         name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
         type:PostalAddress
      name:University of Scienaces and Technologies of Lille
      address:
         name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
         type:PostalAddress
      name:Université Lille Nord de France
      address:
         name:Université Lille Nord de France, Lille, France
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Aurélie Cazet
      affiliation:
            name:University of Scienaces and Technologies of Lille
            address:
               name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
               type:PostalAddress
            type:Organization
            name:Université Lille Nord de France
            address:
               name:Université Lille Nord de France, Lille, France
               type:PostalAddress
            type:Organization
      name:Sylvain Julien
      affiliation:
            name:King's College London
            address:
               name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
               type:PostalAddress
            type:Organization
      name:Marie Bobowski
      affiliation:
            name:University of Scienaces and Technologies of Lille
            address:
               name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
               type:PostalAddress
            type:Organization
            name:Université Lille Nord de France
            address:
               name:Université Lille Nord de France, Lille, France
               type:PostalAddress
            type:Organization
      name:Joy Burchell
      affiliation:
            name:King's College London
            address:
               name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
               type:PostalAddress
            type:Organization
      name:Philippe Delannoy
      affiliation:
            name:University of Scienaces and Technologies of Lille
            address:
               name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
               type:PostalAddress
            type:Organization
            name:Université Lille Nord de France
            address:
               name:Université Lille Nord de France, Lille, France
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
      name:Université Lille Nord de France, Lille, France
      name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
      name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
      name:Université Lille Nord de France, Lille, France
      name:Breast Cancer Biology Group, Research Oncology, King's College London, London, UK
      name:Structural and Functional Glycobiology Unit, UMR CNRS 8576, University of Scienaces and Technologies of Lille, Villeneuve d'Ascq, France
      name:Université Lille Nord de France, Lille, France

External Links {🔗}(310)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

5.33s.

LINK . SPRINGER . COM {}