We are analyzing https://link.springer.com/article/10.1186/1478-811x-6-4.

Title:
Cytoplasmic signaling in the control of mitochondrial uproar? | Cell Communication and Signaling
Description:
The concept of a pre-emptive strike as a good means to prevent greater harm may be frequently over-stressed in daily life. However, biological systems in a homeostatic balance are prepared to withstand a certain degree of hostile fire by rather passive means. This also applies to the maintenance of cell survival, where a plethora of protective proteins provide safeguard against erroneous activation of death pathways. Apart from these mechanisms active processes are also essential for the maintenance of cellular homeostasis, commonly referred to as survival signaling. Frequently their targets may be mitochondrial, assuring organelle integrity, which is essential for continued energy production and survival. Transient or permanent failures in these cellular defense strategies result in pathophysiological conditions, which manifest themselves e.g. as cancer or ischemia/reperfusion-associated organ damage.
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Keywords {🔍}

pubmed, mitochondrial, article, google, scholar, cas, cell, mitochondria, protein, signaling, oxygen, kinase, ros, ampk, energy, activation, production, biol, cellular, phosphorylation, cells, function, survival, death, reactive, ampactivated, role, atp, central, conditions, membrane, physiol, pathways, damage, species, control, apoptosis, growth, oxidative, levels, cancer, potential, transplantation, fusion, drp, glucose, increased, sci, mechanisms, stress,

Topics {✒️}

5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside infusion amp-activated protein kinase--development open access article kurth-kraczek ej reactive oxygen species amp-activated protein kinase bax/bak promote sumoylation ischemia/reperfusion-induced tissue damage reactive nitrogen species article download pdf charcot-marie-tooth mitochondrial love-hate triangle post-translational modifications regulate cytosolic dynamin-related protein carnitine palmitoyl-coa acyltransferase-1 anti-diabetic drug metformin manuel maglione fusion mitochondrial morphology abolishes pro-apoptotic signals extra-mitochondrial energy production linking mitochondrial dysfunction breathing oxygen-producing ros dynamin-related protein drp1 bax/bak-dependent stimulation surviving oxygen lack ischemia-reperfusion induced injury cellular amp/atp ratio hypoxia-induced ros production planned pre-emptive intervention author information authors actin-dependent mitochondrial motility cell death receptor-dependent mitochondrial outer membrane 5'-amp-activated kinase modify mitochondrial morphology reperfusion/reoxygenation mitochondrial ros reactive hydroxyl radical search mitochondrial fission requires dynamin-related gtpase current view classical view privacy choices/manage cookies p66shc redox protein macmillan-crow la change mitochondrial morphology amp kinase results pro-apoptotic signaling cellular oxygen sensing mitochondrial superoxide production

Questions {❓}

Chipuk JE, Green DR: How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
Cytoplasmic signaling in the control of mitochondrial uproar?
Cytoplasmic signaling in the control of mitochondrial uproar?
Kuznetsov AV, Janakiraman M, Margreiter R, Troppmair J: Regulating cell survival by controlling cellular energy production: novel functions for ancient signaling pathways?

Schema {🗺️}

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         Mitochondrial Reactive Oxygen Species
         Mitochondrial Fission
         Mitochondrial Morphology
         Mitochondrial Fusion
         Cell Biology
         Protein-Ligand Interactions
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