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Title:
Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats | Lipids in Health and Disease
Description:
Background Recent studies have reported the preventive effects of probiotics on obesity. Among commensal bacteria, bifidobacteria is one of the most numerous probiotics in the mammalian gut and are a type of lactic acid bacteria. The aim of this study was to assess the antiobesity and lipid-lowering effects of Bifidobacterium spp. isolated from healthy Korean on high fat diet-induced obese rats. Methods Thirty-six male Sprague-Dawley rats were divided into three groups as follows: (1) SD group, fed standard diet; (2) HFD group, fed high fat diet; and (3) HFD-LAB group, fed high fat diet supplemented with LAB supplement (B. pseudocatenulatum SPM 1204, B. longum SPM 1205, and B. longum SPM 1207; 108 ~ 109 CFU). After 7 weeks, the body, organ, and fat weights, food intake, blood serum levels, fecal LAB counts, and harmful enzyme activities were measured. Results Administration of LAB reduced body and fat weights, blood serum levels (TC, HDL-C, LDL-C, triglyceride, glucose, leptin, AST, ALT, and lipase levels), and harmful enzyme activities (β-glucosidase, β-glucuronidase, and tryptophanase), and significantly increased fecal LAB counts. Conclusion These data suggest that Bifidobacterium spp. used in this study may have beneficial antiobesity effects.
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google, scholar, article, group, cas, pubmed, lab, fat, rats, levels, effects, serum, weight, bifidobacterium, body, cholesterol, diet, leptin, enzyme, fecal, activity, high, kim, spm, study, activities, table, bacteria, hfdlab, longum, intestinal, lee, obesity, groups, blood, harmful, reaction, spp, fed, counts, effect, antiobesity, obese, min, probiotics, bifidobacteria, hfd, food, lipase, compared,
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obstructive sleep apnea 2 mm p-nitrophenyl-β-d-glucopyranoside 2 mm p-nitrophenyl-β-d-glucuronide nam joo ha reducing post-prandial hyperglycemia diet-induced obese mice improved diet-induced obesity dmh-induced intestinal tumors open access article high-fat diet feeding hypothalamic-pituitary-gonadal axis [28–30] lactic acid bacteria high fat diet glucose-induced insulin-secretion natural α-amylase inhibitors show anti-obesity effects gut-derived bacterial translocation article download pdf related hepatic steatosis diet-induced resistance male sprague-dawley rats total lab counts central lab animal ph-inducible β-glucuronidase lactic acid intestinal microflora related full access fecal lab counts privacy choices/manage cookies α-amylase assay kit fecal microbiota composition anti-microbial effects omental fat cells bifidobacterium producing exopolysaccharide intestinal microbiota composition reducing inflammatory signaling obese individuals compared 36 male sprague-dawley fecal harmful enzymes ingested lab affect hyung taeck lim potential therapeutic candidates anti-tumor effects massively obese humans anti-proliferative effects hfd-fed groups compared main products formed fed standard diet β-glucuronidase activity related subjects
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headline:Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats
description:Recent studies have reported the preventive effects of probiotics on obesity. Among commensal bacteria, bifidobacteria is one of the most numerous probiotics in the mammalian gut and are a type of lactic acid bacteria. The aim of this study was to assess the antiobesity and lipid-lowering effects of Bifidobacterium spp. isolated from healthy Korean on high fat diet-induced obese rats. Thirty-six male Sprague-Dawley rats were divided into three groups as follows: (1) SD group, fed standard diet; (2) HFD group, fed high fat diet; and (3) HFD-LAB group, fed high fat diet supplemented with LAB supplement (B. pseudocatenulatum SPM 1204, B. longum SPM 1205, and B. longum SPM 1207; 108 ~ 109 CFU). After 7 weeks, the body, organ, and fat weights, food intake, blood serum levels, fecal LAB counts, and harmful enzyme activities were measured. Administration of LAB reduced body and fat weights, blood serum levels (TC, HDL-C, LDL-C, triglyceride, glucose, leptin, AST, ALT, and lipase levels), and harmful enzyme activities (β-glucosidase, β-glucuronidase, and tryptophanase), and significantly increased fecal LAB counts. These data suggest that Bifidobacterium spp. used in this study may have beneficial antiobesity effects.
datePublished:2011-07-12T00:00:00Z
dateModified:2011-07-12T00:00:00Z
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Obstructive Sleep Apnea
Lactic Acid Bacterium
High Density Lipoprotein Cholesterol
Intestinal Microflora
Bifidobacterium Longum
Lipidology
Medical Biochemistry
Clinical Nutrition
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headline:Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats
description:Recent studies have reported the preventive effects of probiotics on obesity. Among commensal bacteria, bifidobacteria is one of the most numerous probiotics in the mammalian gut and are a type of lactic acid bacteria. The aim of this study was to assess the antiobesity and lipid-lowering effects of Bifidobacterium spp. isolated from healthy Korean on high fat diet-induced obese rats. Thirty-six male Sprague-Dawley rats were divided into three groups as follows: (1) SD group, fed standard diet; (2) HFD group, fed high fat diet; and (3) HFD-LAB group, fed high fat diet supplemented with LAB supplement (B. pseudocatenulatum SPM 1204, B. longum SPM 1205, and B. longum SPM 1207; 108 ~ 109 CFU). After 7 weeks, the body, organ, and fat weights, food intake, blood serum levels, fecal LAB counts, and harmful enzyme activities were measured. Administration of LAB reduced body and fat weights, blood serum levels (TC, HDL-C, LDL-C, triglyceride, glucose, leptin, AST, ALT, and lipase levels), and harmful enzyme activities (β-glucosidase, β-glucuronidase, and tryptophanase), and significantly increased fecal LAB counts. These data suggest that Bifidobacterium spp. used in this study may have beneficial antiobesity effects.
datePublished:2011-07-12T00:00:00Z
dateModified:2011-07-12T00:00:00Z
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Obstructive Sleep Apnea
Lactic Acid Bacterium
High Density Lipoprotein Cholesterol
Intestinal Microflora
Bifidobacterium Longum
Lipidology
Medical Biochemistry
Clinical Nutrition
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