We are analyzing https://link.springer.com/article/10.1186/1476-069x-14-1.

Title:
Occupational exposure to wood dust and risk of lung cancer in two population-based case–control studies in Montreal, Canada | Environmental Health
Description:
Background Wood dust is one of the oldest and one of the most common occupational exposures in the world. The present analyses examine the effect of lifetime exposure to wood dust in diverse occupational settings on lung cancer risk. Methods We conducted two population-based case–control studies in Montreal: Study I (1979–1986) included 857 cases and two sets of controls (533 population and 1349 cancer controls), and Study II (1996–2001) comprised 736 cases and 894 population controls. Detailed job histories were obtained by interview and each job was evaluated by expert chemist–hygienists to estimate the likelihood and level of exposure to many substances, one of which was wood dust. Odds ratios (ORs) were computed in relation to different indices of exposure to wood dust, adjusting for several covariates including smoking. Three datasets were analysed: Study I with population controls, Study I with cancer controls, and Study II. Results The most frequently exposed occupations in our study population were in construction, timber and furniture making industries. We found increased risks of lung cancer for substantial cumulative exposure to wood dust in Study I with cancer controls, (OR = 1.4: 95% confidence interval 1.0;-2.0) and in Study II (OR = 1.7: 95% confidence interval 1.1-2.7). There were no excess risks of lung cancer in any of the three datasets among workers whose cumulative exposure was not substantial. These tendencies held equally within strata of low smokers and heavy smokers. Conclusion There was evidence of increased risk of lung cancer among workers with substantial cumulative exposure to wood dust.
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Keywords {🔍}

cancer, exposure, study, wood, dust, lung, occupational, controls, google, scholar, article, studies, smoking, risk, table, results, subjects, cas, population, casecontrol, cases, substantial, workers, med, analysis, research, exposed, occupations, found, smokers, carcinogens, information, siemiatycki, exposures, included, cell, ses, data, health, montreal, canada, including, job, association, years, status, environ, conducted, level, risks,

Topics {✒️}

marie-elise parent & jack siemiatycki hypothesis-generating case–control study community-based case–control studies population-based case–control studies population-based case–control study environmental epidemiology epidemiologic case–control studies nested case–control study industrial profile case–control studies ii smoking profiles open access license article download pdf labor-intensive expert assessment université du québec population-based control group case–control studies benchmark occupational circumstances author information authors case–control study full access world health organization privacy choices/manage cookies belt sanding operations canada research chair paper mill workers université de montréal canadian cancer society author correspondence medical research council specific environmental measurements jack siemiatycki community-based studies ethnic-cultural background preventive medicine socio-demographic characteristics additional epidemiological studies statistics canada catalogue article vallières cancer control series considered medium/heavy smokers occupational cancer studies exact formula depends trained interviewer asked detailed technical probing drawing strong conclusions united states today upper aero-digestive gasoline engine emissions directed acyclic graphs

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Brisson C, Loomis D, Pearce N: Is social class standardisation appropriate in occupational studies?

Schema {🗺️}

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         description:Wood dust is one of the oldest and one of the most common occupational exposures in the world. The present analyses examine the effect of lifetime exposure to wood dust in diverse occupational settings on lung cancer risk. We conducted two population-based case–control studies in Montreal: Study I (1979–1986) included 857 cases and two sets of controls (533 population and 1349 cancer controls), and Study II (1996–2001) comprised 736 cases and 894 population controls. Detailed job histories were obtained by interview and each job was evaluated by expert chemist–hygienists to estimate the likelihood and level of exposure to many substances, one of which was wood dust. Odds ratios (ORs) were computed in relation to different indices of exposure to wood dust, adjusting for several covariates including smoking. Three datasets were analysed: Study I with population controls, Study I with cancer controls, and Study II. The most frequently exposed occupations in our study population were in construction, timber and furniture making industries. We found increased risks of lung cancer for substantial cumulative exposure to wood dust in Study I with cancer controls, (OR = 1.4: 95% confidence interval 1.0;-2.0) and in Study II (OR = 1.7: 95% confidence interval 1.1-2.7). There were no excess risks of lung cancer in any of the three datasets among workers whose cumulative exposure was not substantial. These tendencies held equally within strata of low smokers and heavy smokers. There was evidence of increased risk of lung cancer among workers with substantial cumulative exposure to wood dust.
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