We are analyzing https://link.springer.com/article/10.1007/s44313-024-00010-0.

Title:
The role of next-generation sequencing in hematologic malignancies | Blood Research
Description:
Next-generation sequencing (NGS) allows high-throughput detection of molecular changes in tumors. Over the past 15 years, NGS has rapidly evolved from a promising research tool to a core component of the clinical laboratory. Sequencing of tumor cells provides an important step in detecting somatic driver mutations that not only characterize the disease but also influence treatment decisions. For patients with hematologic malignancies, NGS has been used for accurate classification and diagnosis based on genetic alterations. The recently revised World Health Organization classification and the European LeukemiaNet recommendations for acute myeloid leukemia consider genetic abnormalities as a top priority for diagnosis, prognostication, monitoring of measurable residual disease, and treatment choice. This review aims to present the role and utility of various NGS approaches for the diagnosis, treatment, and follow-up of hemato-oncology patients.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Education
Health & Fitness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,016 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure if the website is profiting.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Link.springer.com might be earning cash quietly, but we haven't detected the monetization method.

Keywords {🔍}

pubmed, article, mutations, google, scholar, leukemia, aml, patients, cas, myeloid, central, acute, sequencing, genetic, ngs, malignancies, clinical, molecular, blood, mrd, hematologic, gene, assay, disease, diagnosis, fusions, nextgeneration, mds, monitoring, targeted, genes, fusion, role, classification, abnormalities, residual, lymphoblastic, prognostic, germline, mutation, cebpa, ddx, ngsbased, research, access, treatment, measurable, testing, sfb, idh,

Topics {✒️}

young-uk cho panel-based error-corrected article download pdf multi-hit tp53 alterations including higher-specification analyzers hematopoietic stem-cell transplantation multipotent stem/progenitor cells flt3-internal tandem duplication ebv-negative burkitt lymphoma forthcoming mrd-based protocols real-time quantitative pcr �b-acute lymphoblastic leukemia ngs-based chimerism assay fda-approved targeted therapy ngs-based mrd assay aml-defining gene fusions aml include flt3-itd ngs-based mrd monitoring targeted rna sequencing article cho promising research tool describes cebpa-mutant aml measurable residual disease acute lymphoblastic leukemia age-related clonal hematopoiesis privacy choices/manage cookies clinical hematology testing myeloid precursor lesions hairy cell leukemia international working group nat rev cancer main manuscript text plasma cell myeloma single-nucleotide polymorphisms generation sequencing assay breaking points based comprehensive genetic testing acute myeloid leukemia international expert panel central role gene expression profiling mrd-based protocol ngs-based mrd european economic area age-related ch adverse risk group subclonal genetic markers additional gene fusions full access frame mutations affecting

Questions {❓}

Measurable residual disease in acute lymphoblastic leukemia: How low is low enough?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:The role of next-generation sequencing in hematologic malignancies
         description:Next-generation sequencing (NGS) allows high-throughput detection of molecular changes in tumors. Over the past 15 years, NGS has rapidly evolved from a promising research tool to a core component of the clinical laboratory. Sequencing of tumor cells provides an important step in detecting somatic driver mutations that not only characterize the disease but also influence treatment decisions. For patients with hematologic malignancies, NGS has been used for accurate classification and diagnosis based on genetic alterations. The recently revised World Health Organization classification and the European LeukemiaNet recommendations for acute myeloid leukemia consider genetic abnormalities as a top priority for diagnosis, prognostication, monitoring of measurable residual disease, and treatment choice. This review aims to present the role and utility of various NGS approaches for the diagnosis, treatment, and follow-up of hemato-oncology patients.
         datePublished:2024-03-06T00:00:00Z
         dateModified:2024-03-06T00:00:00Z
         pageStart:1
         pageEnd:5
         license:http://creativecommons.org/licenses/by/4.0/
         sameAs:https://doi.org/10.1007/s44313-024-00010-0
         keywords:
            Next-generation sequencing
            Leukemia
            Diagnosis
            Prognosis
            Monitoring
            Hematology
            Oncology
         image:
         isPartOf:
            name:Blood Research
            issn:
               2288-0011
               2287-979X
            volumeNumber:59
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Nature Singapore
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Young-Uk Cho
               url:http://orcid.org/0000-0002-4403-8989
               affiliation:
                     name:University of Ulsan College of Medicine
                     address:
                        name:Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:The role of next-generation sequencing in hematologic malignancies
      description:Next-generation sequencing (NGS) allows high-throughput detection of molecular changes in tumors. Over the past 15 years, NGS has rapidly evolved from a promising research tool to a core component of the clinical laboratory. Sequencing of tumor cells provides an important step in detecting somatic driver mutations that not only characterize the disease but also influence treatment decisions. For patients with hematologic malignancies, NGS has been used for accurate classification and diagnosis based on genetic alterations. The recently revised World Health Organization classification and the European LeukemiaNet recommendations for acute myeloid leukemia consider genetic abnormalities as a top priority for diagnosis, prognostication, monitoring of measurable residual disease, and treatment choice. This review aims to present the role and utility of various NGS approaches for the diagnosis, treatment, and follow-up of hemato-oncology patients.
      datePublished:2024-03-06T00:00:00Z
      dateModified:2024-03-06T00:00:00Z
      pageStart:1
      pageEnd:5
      license:http://creativecommons.org/licenses/by/4.0/
      sameAs:https://doi.org/10.1007/s44313-024-00010-0
      keywords:
         Next-generation sequencing
         Leukemia
         Diagnosis
         Prognosis
         Monitoring
         Hematology
         Oncology
      image:
      isPartOf:
         name:Blood Research
         issn:
            2288-0011
            2287-979X
         volumeNumber:59
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Nature Singapore
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Young-Uk Cho
            url:http://orcid.org/0000-0002-4403-8989
            affiliation:
                  name:University of Ulsan College of Medicine
                  address:
                     name:Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Blood Research
      issn:
         2288-0011
         2287-979X
      volumeNumber:59
Organization:
      name:Springer Nature Singapore
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Ulsan College of Medicine
      address:
         name:Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Young-Uk Cho
      url:http://orcid.org/0000-0002-4403-8989
      affiliation:
            name:University of Ulsan College of Medicine
            address:
               name:Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

External Links {🔗}(164)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.22s.

LINK . SPRINGER . COM {}