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int/news-room/fact-sheets/detail/cancer org/dietandcancer/cancer-trends/skin-cancer-statistics squamous-cell-skin-cancer/treating/targeted-therapy org/patient-eng/melanoma-treatment/targeted-therapy/ /cancer-types/skin-cancer/treatments/surgery squamous-cell-skin-cancer/treating dual-modality imaging functions targeted chemo-photothermal therapy org/treatment-resources/mohs-surgery/ net/cancer-types/melanoma/statistics mesoporous silica nanoparticles-polymerpolyethylenimine mesoporous silica-based nanocarriers image-guided surgical treatment month download article/chapter side-effects/treatment-types/chemotherapy/ light-induced hydrogel based antigen/adjuvant-loaded nanoparticles silicotungstic acid/zirconia immobilized mapk-targeted drug delivered molecularly targeted therapy /research_and_development/what_we_are_working_on/oncology/things recombinant interferon alpha-2b reversible polypeptide-engineered valve spherical silica micro/nanomaterials human monoclonal anti-pd-1 /melanoma-skin-cancer/melanoma-treatment mesoporous ga-sba-1 catalysts pure silica-based dds microneedle-assisted topical delivery stimuli responsive nanoparticles effective cancer-targeted probes merkel cell carcinoma optimal drug/sirna combination mesoporous silica nanoparticles squamous cell carcinoma thirty-year experience overview anticancer drug transport—synthesis enhanced cancer-directed uptake long-term survival data drug delivery systems active drug targeting photo-active agents multimodal silica nanoparticles targeted cancer therapy silica-based nanomaterials basal cell carcinoma synergistic photothermal therapy anti-cancer therapy mesoporous silica nanoflakes mesoporous silica flakes

Questions {❓}

• How is chemotherapy used to treat cancer?
• Mor, Targeted cancer therapy–are the days of systemic chemotherapy numbered?

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         description:Skin cancer has emerged as one of the leading types of cancers in the world, causing a high impact on the global burden of health and the economy. Basal cell and squamous cell carcinoma are the localized forms of skin cancer with a high prevalence and can be treated with a high success rate. However, melanoma, a rare type of skin cancer with a high mortality rate, can metastasize and invade other parts of the body. Various skin cancer treatment approaches have been developed and advanced from localized to systemic treatment over the years to improve the low success rate associated with skin cancer, especially metastatic melanoma. The systemic treatment of skin cancer is highly benefitted by drug delivery systems (DDS) designed to function with much higher specificity and lower side effects than the direct treatment with drugs. While many nanomaterials based DDS have been developed in the past few years to take advantage of the small size and high functionality of nanomaterials, silica-based nanomaterials have recently emerged as the flexible DDS with a high biocompatibility, good clearance, a high drug loading capacity, and versatility to attach several drugs and targeting agents to its surface. In this review, recent progress in the treatment of melanoma using silica-based nanomaterials and their hybrids is discussed, highlighting the versatility and potential of these emerging nanomaterials as the DDS for delivering various molecules, including drugs and immunotherapy agents, peptides, and radio- and photo-active agents. The review also introduces various therapies available for the treatment of melanoma, including surgery, chemotherapy, targeted therapy, phototherapy, and immunotherapy and discusses the improvement in these therapies based on silica-based DDS. The review also highlights the role of silica nanomaterials and their hybrids in delivering combination therapy and the advantages of silica nanohybrids over pure silica-based DDS. Finally, we summarize the present status of silica-based nanomaterials in melanoma treatment and the current challenges that have to be solved for the clinical translation of these materials as DDS.
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      description:Skin cancer has emerged as one of the leading types of cancers in the world, causing a high impact on the global burden of health and the economy. Basal cell and squamous cell carcinoma are the localized forms of skin cancer with a high prevalence and can be treated with a high success rate. However, melanoma, a rare type of skin cancer with a high mortality rate, can metastasize and invade other parts of the body. Various skin cancer treatment approaches have been developed and advanced from localized to systemic treatment over the years to improve the low success rate associated with skin cancer, especially metastatic melanoma. The systemic treatment of skin cancer is highly benefitted by drug delivery systems (DDS) designed to function with much higher specificity and lower side effects than the direct treatment with drugs. While many nanomaterials based DDS have been developed in the past few years to take advantage of the small size and high functionality of nanomaterials, silica-based nanomaterials have recently emerged as the flexible DDS with a high biocompatibility, good clearance, a high drug loading capacity, and versatility to attach several drugs and targeting agents to its surface. In this review, recent progress in the treatment of melanoma using silica-based nanomaterials and their hybrids is discussed, highlighting the versatility and potential of these emerging nanomaterials as the DDS for delivering various molecules, including drugs and immunotherapy agents, peptides, and radio- and photo-active agents. The review also introduces various therapies available for the treatment of melanoma, including surgery, chemotherapy, targeted therapy, phototherapy, and immunotherapy and discusses the improvement in these therapies based on silica-based DDS. The review also highlights the role of silica nanomaterials and their hybrids in delivering combination therapy and the advantages of silica nanohybrids over pure silica-based DDS. Finally, we summarize the present status of silica-based nanomaterials in melanoma treatment and the current challenges that have to be solved for the clinical translation of these materials as DDS.
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• Learn how profitable https://doi.org/10.1016%2Fj.molcata.2005.03.014 is on a monthly basis
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• What's the monthly income of https://doi.org/10.1016%2Fj.msec.2006.05.012?
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• Revenue of https://doi.org/10.1016%2Fj.micromeso.2012.01.005
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