We are analyzing https://link.springer.com/article/10.1007/s40820-022-00922-5.

Title:
Importance of Standardizing Analytical Characterization Methodology for Improved Reliability of the Nanomedicine Literature | Nano-Micro Letters
Description:
Understanding the interaction between biological structures and nanoscale technologies, dubbed the nano-bio interface, is required for successful development of safe and efficient nanomedicine products. The lack of a universal reporting system and decentralized methodologies for nanomaterial characterization have resulted in a low degree of reliability and reproducibility in the nanomedicine literature. As such, there is a strong need to establish a characterization system to support the reproducibility of nanoscience data particularly for studies seeking clinical translation. Here, we discuss the existing key standards for addressing robust characterization of nanomaterials based on their intended use in medical devices or as pharmaceuticals. We also discuss the challenges surrounding implementation of such standard protocols and their implication for translation of nanotechnology into clinical practice. We, however, emphasize that practical implementation of standard protocols in experimental laboratories requires long-term planning through integration of stakeholders including institutions and funding agencies.
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Keywords {🔍}

characterization, nanomaterials, standards, article, nanomedicine, devices, google, scholar, medical, size, reproducibility, nanoparticles, iso, nanomaterial, analytical, standard, nanotechnology, nanoparticle, biological, data, research, reporting, intended, dls, nanoscience, products, guidelines, type, including, studies, clinical, sample, toxicity, literature, results, health, based, related, materials, requirements, methods, surface, isotr, mpl, analysis, nanotechnologies, lack, validation, academic, nat,

Topics {✒️}

eu/en/publication-detail/-/publication/e9899821-e4d4-4ceb-aada-0c62ce6cfcd3 gov/news-events/press-announcements/fda-takes-action-protect-patients-risk textured-breast-implants-requests-allergan gov/nano/research/ncl/protocolscapabilities commercial fda-approved nano-drugs multi-billion dollar industry chan zuckerberg biohub investigator promising pre-clinical candidates nano-enabled consumer products polymer-conjugated carbon nanotubes commercially-procured carboxylated nanotubes high-performance liquid chromatography science grant de-sc0020366 nano-enabled medical products standard operating procedures article download pdf bio-nano experimental literature nano-bio interface literature nanobiomedicine search search full size image cancer nanomedicines—lessons learned nano-micro lett nano-based medical devices protect patient health privacy choices/manage cookies european nanomedicine characterization laboratory solution-phase characterization methods publication remains sporadic workers recently proposed article google scholar standard operation procedures enhance chemodynamic therapy current standard protocols full access nano-bio interface global wound care nanomaterial-incorporated medical devices technical report presents joint assay protocol orthogonal analytical techniques versus nano-objects multiple experimental replicates including pore size published research works umbrella term defined plagues multiple fields misrepresent actual findings multiple fields coalescing nanotechnology-based medical devices glp requires establishing

Schema {🗺️}

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         headline:Importance of Standardizing Analytical Characterization Methodology for Improved Reliability of the Nanomedicine Literature
         description: Understanding the interaction between biological structures and nanoscale technologies, dubbed the nano-bio interface, is required for successful development of safe and efficient nanomedicine products. The lack of a universal reporting system and decentralized methodologies for nanomaterial characterization have resulted in a low degree of reliability and reproducibility in the nanomedicine literature. As such, there is a strong need to establish a characterization system to support the reproducibility of nanoscience data particularly for studies seeking clinical translation. Here, we discuss the existing key standards for addressing robust characterization of nanomaterials based on their intended use in medical devices or as pharmaceuticals. We also discuss the challenges surrounding implementation of such standard protocols and their implication for translation of nanotechnology into clinical practice. We, however, emphasize that practical implementation of standard protocols in experimental laboratories requires long-term planning through integration of stakeholders including institutions and funding agencies.
         datePublished:2022-08-20T00:00:00Z
         dateModified:2022-08-20T00:00:00Z
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            Nanomedicine
            Standard protocols
            Reproducibility
            Nanomedicine devices
            Nanotechnology and Microengineering
            Nanotechnology
            Nanoscale Science and Technology
            Energy
            general
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                        name:California Institute for Quantitative Biosciences, University of California, Berkeley, USA
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      headline:Importance of Standardizing Analytical Characterization Methodology for Improved Reliability of the Nanomedicine Literature
      description: Understanding the interaction between biological structures and nanoscale technologies, dubbed the nano-bio interface, is required for successful development of safe and efficient nanomedicine products. The lack of a universal reporting system and decentralized methodologies for nanomaterial characterization have resulted in a low degree of reliability and reproducibility in the nanomedicine literature. As such, there is a strong need to establish a characterization system to support the reproducibility of nanoscience data particularly for studies seeking clinical translation. Here, we discuss the existing key standards for addressing robust characterization of nanomaterials based on their intended use in medical devices or as pharmaceuticals. We also discuss the challenges surrounding implementation of such standard protocols and their implication for translation of nanotechnology into clinical practice. We, however, emphasize that practical implementation of standard protocols in experimental laboratories requires long-term planning through integration of stakeholders including institutions and funding agencies.
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      dateModified:2022-08-20T00:00:00Z
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      pageEnd:15
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      keywords:
         Characterization
         Nanomedicine
         Standard protocols
         Reproducibility
         Nanomedicine devices
         Nanotechnology and Microengineering
         Nanotechnology
         Nanoscale Science and Technology
         Energy
         general
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            affiliation:
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                  address:
                     name:Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, USA
                     type:PostalAddress
                  type:Organization
            type:Person
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            affiliation:
                  name:University of California
                  address:
                     name:Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, USA
                     type:PostalAddress
                  type:Organization
                  name:Innovative Genomics Institute
                  address:
                     name:Innovative Genomics Institute, Berkeley, USA
                     type:PostalAddress
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                  address:
                     name:California Institute for Quantitative Biosciences, University of California, Berkeley, USA
                     type:PostalAddress
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                     name:Chan Zuckerberg Biohub, San Francisco, USA
                     type:PostalAddress
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         name:Department of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar
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         type:PostalAddress
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         type:PostalAddress
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         type:PostalAddress
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         name:Chan Zuckerberg Biohub, San Francisco, USA
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               name:Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
               type:PostalAddress
            type:Organization
            name:College of Health Sciences, QU Health, Qatar University
            address:
               name:Department of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar
               type:PostalAddress
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      affiliation:
            name:University of California
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               name:Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, USA
               type:PostalAddress
            type:Organization
      name:Markita P. Landry
      affiliation:
            name:University of California
            address:
               name:Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, USA
               type:PostalAddress
            type:Organization
            name:Innovative Genomics Institute
            address:
               name:Innovative Genomics Institute, Berkeley, USA
               type:PostalAddress
            type:Organization
            name:University of California
            address:
               name:California Institute for Quantitative Biosciences, University of California, Berkeley, USA
               type:PostalAddress
            type:Organization
            name:Chan Zuckerberg Biohub
            address:
               name:Chan Zuckerberg Biohub, San Francisco, USA
               type:PostalAddress
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      email:[email protected]
      name:Morteza Mahmoudi
      affiliation:
            name:Michigan State University
            address:
               name:Department of Radiology and Precision Health Program, Michigan State University, East Lansing, USA
               type:PostalAddress
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      email:[email protected]
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      name:Department of Radiology and Precision Health Program, Michigan State University, East Lansing, USA
      name:Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
      name:Department of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar
      name:Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, USA
      name:Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, USA
      name:Innovative Genomics Institute, Berkeley, USA
      name:California Institute for Quantitative Biosciences, University of California, Berkeley, USA
      name:Chan Zuckerberg Biohub, San Francisco, USA
      name:Department of Radiology and Precision Health Program, Michigan State University, East Lansing, USA

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