We are analyzing https://link.springer.com/article/10.1007/s40263-016-0370-3.

Title:
May the Force Be With You: The Light and Dark Sides of the Microbiota–Gut–Brain Axis in Neuropsychiatry | CNS Drugs
Description:
The role of the gut microbiota in health and disease is becoming increasingly recognized. The microbiota–gut–brain axis is a bi-directional pathway between the brain and the gastrointestinal system. The bacterial commensals in our gut can signal to the brain through a variety of mechanisms, which are slowly being resolved. These include the vagus nerve, immune mediators and microbial metabolites, which influence central processes such as neurotransmission and behaviour. Dysregulation in the composition of the gut microbiota has been identified in several neuropsychiatric disorders, such as autism, schizophrenia and depression. Moreover, preclinical studies suggest that they may be the driving force behind the behavioural abnormalities observed in these conditions. Understanding how bacterial commensals are involved in regulating brain function may lead to novel strategies for development of microbiota-based therapies for these neuropsychiatric disorders.
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Keywords {🔍}

microbiota, gut, internet, mice, brain, acid, effect, lactobacillus, bacterial, pubmed, levels, autism, google, scholar, article, effects, probiotic, behaviour, expression, axis, increased, depression, central, elsevier, disorders, shown, probiotics, children, activation, increase, httplinkinghubelseviercomretrievepiis, dinan, role, gastrointestinal, immune, microbial, nerve, stress, production, treatment, response, rats, cas, conditions, bacteria, intestinal, colleagues, cryan, composition, observed,

Topics {✒️}

dbfrom=pubmed&id=16717182&retmode=ref&cmd=prlinks\npapers3 n-methyl-d-aspartate receptor subunits artid=4149359&tool=pmcentrez&rendertype=abstract artid=3747729&tool=pmcentrez&rendertype=abstract artid=1574260&tool=pmcentrez&rendertype=abstract artid=3638389&tool=pmcentrez&rendertype=abstract artid=2656143&tool=pmcentrez&rendertype=abstract artid=3705355&tool=pmcentrez&rendertype=abstract artid=1728209&tool=pmcentrez&rendertype=abstract artid=4315778&tool=pmcentrez&rendertype=abstract artid=2814855&tool=pmcentrez&rendertype=abstract artid=2892549&tool=pmcentrez&rendertype=abstract artid=3818006&tool=pmcentrez&rendertype=abstract artid=3625915&tool=pmcentrez&rendertype=abstract gov/pmc/articles/pmc3469551/pdf/pone short-chain fatty acids low-abundance cyanobacteria/chloroplast genus gram-negative bacteroides genus lactic acid–producing bacteria—produce irritable bowel syndrome glial-derived neurotrophic factor specific-pathogen-free mice microbiota–gut–brain axis accompanies finnish pre-school children article download pdf germ-free mice independently dorsal vagal complex high gamma-aminobutyric acid brain-derived neurotropic factor de theije cgm inducing long-lasting metabolic modulate stress-induced activation improving long-term potentiation anti-inflammatory cytokine blocked germ-free mice translated glial-derived neurotrophic factors tlr2-mediated cd39 signalling nutrient-induced bacterial growth lactic acid–producing bacteria bi-directional communication network gut-brain neural circuits inducing long-lasting alterations γ-aminobutyric acid production olanzapine-induced metabolic dysfunction large-scale clinical trials age-related cognitive decline curr opin gastroenterol social stressor alters gaba γ-aminobutyric acid gov/entrez/eutils/elink

Questions {❓}

6 Conclusions and Future Perspectives: A New Hope?
Altered brain-gut axis in autism: comorbidity or causative mechanisms?
How might the altered microbiota found in children with ASD give rise to autistic behaviours/symptoms?
Melancholic microbes: a link between gut microbiota and depression?
Sex-specific differences in side effects of psychotropic drugs: genes or gender?
Com/linkback/openurl?

Schema {🗺️}

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         headline:May the Force Be With You: The Light and Dark Sides of the Microbiota–Gut–Brain Axis in Neuropsychiatry
         description:The role of the gut microbiota in health and disease is becoming increasingly recognized. The microbiota–gut–brain axis is a bi-directional pathway between the brain and the gastrointestinal system. The bacterial commensals in our gut can signal to the brain through a variety of mechanisms, which are slowly being resolved. These include the vagus nerve, immune mediators and microbial metabolites, which influence central processes such as neurotransmission and behaviour. Dysregulation in the composition of the gut microbiota has been identified in several neuropsychiatric disorders, such as autism, schizophrenia and depression. Moreover, preclinical studies suggest that they may be the driving force behind the behavioural abnormalities observed in these conditions. Understanding how bacterial commensals are involved in regulating brain function may lead to novel strategies for development of microbiota-based therapies for these neuropsychiatric disorders.
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      headline:May the Force Be With You: The Light and Dark Sides of the Microbiota–Gut–Brain Axis in Neuropsychiatry
      description:The role of the gut microbiota in health and disease is becoming increasingly recognized. The microbiota–gut–brain axis is a bi-directional pathway between the brain and the gastrointestinal system. The bacterial commensals in our gut can signal to the brain through a variety of mechanisms, which are slowly being resolved. These include the vagus nerve, immune mediators and microbial metabolites, which influence central processes such as neurotransmission and behaviour. Dysregulation in the composition of the gut microbiota has been identified in several neuropsychiatric disorders, such as autism, schizophrenia and depression. Moreover, preclinical studies suggest that they may be the driving force behind the behavioural abnormalities observed in these conditions. Understanding how bacterial commensals are involved in regulating brain function may lead to novel strategies for development of microbiota-based therapies for these neuropsychiatric disorders.
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