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Title:
Oral Lichen Planus: An Update on Diagnosis and Management | American Journal of Clinical Dermatology
Description:
Oral lichen planus (OLP) is a chronic inflammatory disease whose pathogenesis involves a T-cell mediated, epithelium-directed inflammation in response to unknown antigen(s). The disease evolves by intermittent flares and displays polymorphous clinical features (reticular, erosive, atrophic, plaque, papular, bullous, etc.). When present, symptoms vary depending on the clinical form and range from discomfort to severe pain. Topical superpotent corticosteroids constitute the first-line treatment of symptomatic flares, whereas a wide range of second/third-line treatments are available among topical calcineurin inhibitors, systemic corticosteroids, systemic retinoids, topical/systemic immunomodulators, etc. Follow-up of patients is necessary to detect transformation into squamous cell carcinoma, occurring in approximately 1% of patients.
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Keywords {🔍}
oral, pubmed, google, scholar, article, lichen, planus, cas, dermatol, review, med, treatment, systematic, clinical, pathol, study, erosive, topical, dis, surg, central, patients, metaanalysis, acad, lesions, clin, management, lichenoid, radiol, diagnosis, samimi, gonzálezmoles, efficacy, severe, gonzálezruiz, dent, malignant, case, venereol, france, applicable, systemic, therapy, related, warnakulasuriya, carrozzo, endod, evaluation, tours, privacy,
Topics {✒️}
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Questions {❓}
- Do metal restorations in mouth alter clinical and histological appearance of oral lichen planus?
- Drug-induced oral lichenoid reactions: a real clinical entity?
- What should we accept based on the available evidence?
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