We are analyzing https://link.springer.com/article/10.1007/s12325-020-01346-6.

Title:
Psoriasis and Cardiovascular Risk: A Comprehensive Review | Advances in Therapy
Description:
Psoriasis is a systemic inflammatory disorder that involves complex pathogenic interactions between the innate and adaptive immune systems. Individuals with psoriasis have an increased risk of developing other chronic health diseases such cardiovascular disorders. The high incidence of cardiovascular events in the population with psoriasis could be explained by several mechanisms. The high prevalence of traditional cardiovascular risk factors and metabolic abnormalities contributes to the high cardiovascular burden in patients with psoriasis. Likewise, the presence of systemic inflammation in combination with metabolic abnormalities may act in a synergistic manner to increase cardiovascular risk in these patients. This review focused on epidemiologic and clinical evidence linking psoriasis to cardiovascular risk factors and cardiovascular disease. We described the possible pathophysiological mechanisms that justify this association and analyzed the best way to stratify the cardiovascular risk in patients with psoriasis. We also described the usefulness of the therapies frequently used in cardiovascular prevention and analyzed the impact of the specific psoriasis medication on cardiovascular risk factors or major atherosclerotic events. Knowledge of the application of different cardiovascular prevention strategies could mean an advantage in performing the difficult task of estimating cardiovascular risk and treating cardiovascular risk factors in this particular group of patients.
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28 years and 1 months (reg. 1997-05-29).

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Keywords {🔍}

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Topics {✒️}

2018 aha/acc/aacvpr/aapa/abc/acpm/ada/ags/apha/aspc/nla/pcna guideline granulocyte-monocyte colony-stimulating factor martín lobo & graciela molinero mitogen-activated protein kinase article download pdf randomized placebo-controlled trial population-based case–control study acc/aha carotid mid-intimal thickness pulse-wave velocity measurement placebo-controlled clinical trial angiotensin-converting enzyme inhibitors recently published meta-analysis pro-inflammatory cytokine profile steroidal anti-inflammatory drugs long-term extension data block beta-adrenergic receptors moose-compliant meta-analysis long-term safety profiles randomized controlled trials promoting low-grade inflammation standard/low-dose statins population-based cohort study cross-sectional study developed lipid-lowering statin therapy randomized clinical trials case-control study showed privacy choices/manage cookies prospective case-series study tumor necrosis factor de faria ap gonzález-gay ma miranda-filloy ja small ldl particles total/hdl cholesterol ratio recent research shows pulse wave velocity de souza santos área de consensos cardiology/american heart association dipeptidylpeptidase-iv inhibitor cardiovascular risk stratification inflammatory joint disorders full access achieve accurate stratification mehta nn recent research suggests executive summary future cardiovascular event cardiovascular risk factors

Questions {❓}

Cardiovascular risk profiles in a lupus cohort: what do different calculators tell us?
Do psoriasis patients engage in vigorous physical activity?
Psoriasis and atherosclerosis: two plaques, one syndrome?
Psoriasis and cardiovascular disorders: association or epiphenomenon?
Should all patients with psoriasis receive statins?
Subclinical cardiovascular disease in plaque psoriasis: association or causal link?

Schema {🗺️}

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         description:Psoriasis is a systemic inflammatory disorder that involves complex pathogenic interactions between the innate and adaptive immune systems. Individuals with psoriasis have an increased risk of developing other chronic health diseases such cardiovascular disorders. The high incidence of cardiovascular events in the population with psoriasis could be explained by several mechanisms. The high prevalence of traditional cardiovascular risk factors and metabolic abnormalities contributes to the high cardiovascular burden in patients with psoriasis. Likewise, the presence of systemic inflammation in combination with metabolic abnormalities may act in a synergistic manner to increase cardiovascular risk in these patients. This review focused on epidemiologic and clinical evidence linking psoriasis to cardiovascular risk factors and cardiovascular disease. We described the possible pathophysiological mechanisms that justify this association and analyzed the best way to stratify the cardiovascular risk in patients with psoriasis. We also described the usefulness of the therapies frequently used in cardiovascular prevention and analyzed the impact of the specific psoriasis medication on cardiovascular risk factors or major atherosclerotic events. Knowledge of the application of different cardiovascular prevention strategies could mean an advantage in performing the difficult task of estimating cardiovascular risk and treating cardiovascular risk factors in this particular group of patients.
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      headline:Psoriasis and Cardiovascular Risk: A Comprehensive Review
      description:Psoriasis is a systemic inflammatory disorder that involves complex pathogenic interactions between the innate and adaptive immune systems. Individuals with psoriasis have an increased risk of developing other chronic health diseases such cardiovascular disorders. The high incidence of cardiovascular events in the population with psoriasis could be explained by several mechanisms. The high prevalence of traditional cardiovascular risk factors and metabolic abnormalities contributes to the high cardiovascular burden in patients with psoriasis. Likewise, the presence of systemic inflammation in combination with metabolic abnormalities may act in a synergistic manner to increase cardiovascular risk in these patients. This review focused on epidemiologic and clinical evidence linking psoriasis to cardiovascular risk factors and cardiovascular disease. We described the possible pathophysiological mechanisms that justify this association and analyzed the best way to stratify the cardiovascular risk in patients with psoriasis. We also described the usefulness of the therapies frequently used in cardiovascular prevention and analyzed the impact of the specific psoriasis medication on cardiovascular risk factors or major atherosclerotic events. Knowledge of the application of different cardiovascular prevention strategies could mean an advantage in performing the difficult task of estimating cardiovascular risk and treating cardiovascular risk factors in this particular group of patients.
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