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Genome-wide survey of Alternative Splicing in Sorghum Bicolor | Physiology and Molecular Biology of Plants
Description:
Sorghum bicolor is a member of grass family which is an attractive model plant for genome study due to interesting genome features like low genome size. In this research, we performed comprehensive investigation of Alternative Splicing and ontology aspects of genes those have undergone these events in sorghum bicolor. We used homology based alignments between gene rich transcripts, represented by tentative consensus (TC) transcript sequences, and genomic scaffolds to deduce the structure of genes and identify alternatively spliced transcripts in sorghum. Using homology mapping of assembled expressed sequence tags with genomics data, we identified 2,137 Alternative Splicing events in S. bicolor. Our study showed that complex events and intron retention are the main types of Alternative Splicing events in S. bicolor and highlights the prevalence of splicing site recognition for definition of introns in this plant. Annotations of the alternatively spliced genes revealed that they represent diverse biological process and molecular functions, suggesting a fundamental role for Alternative Splicing in affecting the development and physiology of S. bicolor.
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pubmed, article, splicing, alternative, google, scholar, cas, plant, genome, central, res, genomewide, arabidopsis, bicolor, events, analysis, plants, sorghum, access, biol, privacy, cookies, content, data, research, molecular, panahi, genes, gene, alternatively, spliced, sequence, intron, nucleic, acids, information, publish, search, survey, june, bahman, transcripts, genomics, retention, proc, natl, acad, sci, log, journal,
Topics {βοΈ}
month download article/chapter nonsense-mediated mrna decay alternative pre-mrna splicing pre-mrnas affects mechanisms related subjects tissue-specific alternative splicing full-length cdna sequences full article pdf cross-species est conservation comprehensive splice-site analysis pre-messenger rnas privacy choices/manage cookies article panahi genome-wide survey alternative splicing events meshgin shahr chloroplast genome characteristics attractive model plant plant sr proteins full-length cdnas genome-wide mapping species-specific variation alternative splicing evolve alternative splicing based alternative splicing results alternative splicing landscape performed comprehensive investigation complex events cross-kingdom patterns genome-wide landscape organ-specific differences exon junction microarrays extensive exon reshuffling genome-wide analysis genome wide identification molecular biology european economic area glycine cleavage system genome-wide analyses article physiology bahman panahi sequence features responsible low genome size splice-site pairing conditions privacy policy article log splicing site recognition homology based alignments evolutionary time coupled de souza sj
Questions {β}
- Ast G (2004) How did alternative splicing evolve?
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headline:Genome-wide survey of Alternative Splicing in Sorghum Bicolor
description:
Sorghum bicolor is a member of grass family which is an attractive model plant for genome study due to interesting genome features like low genome size. In this research, we performed comprehensive investigation of Alternative Splicing and ontology aspects of genes those have undergone these events in sorghum bicolor. We used homology based alignments between gene rich transcripts, represented by tentative consensus (TC) transcript sequences, and genomic scaffolds to deduce the structure of genes and identify alternatively spliced transcripts in sorghum. Using homology mapping of assembled expressed sequence tags with genomics data, we identified 2,137 Alternative Splicing events in S. bicolor. Our study showed that complex events and intron retention are the main types of Alternative Splicing events in S. bicolor and highlights the prevalence of splicing site recognition for definition of introns in this plant. Annotations of the alternatively spliced genes revealed that they represent diverse biological process and molecular functions, suggesting a fundamental role for Alternative Splicing in affecting the development and physiology of S. bicolor.
datePublished:2014-06-29T00:00:00Z
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Alternative splicing
Ontology
Complex events
Intron retention
Plant Sciences
Plant Physiology
Biological and Medical Physics
Biophysics
Cell Biology
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description:
Sorghum bicolor is a member of grass family which is an attractive model plant for genome study due to interesting genome features like low genome size. In this research, we performed comprehensive investigation of Alternative Splicing and ontology aspects of genes those have undergone these events in sorghum bicolor. We used homology based alignments between gene rich transcripts, represented by tentative consensus (TC) transcript sequences, and genomic scaffolds to deduce the structure of genes and identify alternatively spliced transcripts in sorghum. Using homology mapping of assembled expressed sequence tags with genomics data, we identified 2,137 Alternative Splicing events in S. bicolor. Our study showed that complex events and intron retention are the main types of Alternative Splicing events in S. bicolor and highlights the prevalence of splicing site recognition for definition of introns in this plant. Annotations of the alternatively spliced genes revealed that they represent diverse biological process and molecular functions, suggesting a fundamental role for Alternative Splicing in affecting the development and physiology of S. bicolor.
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Alternative splicing
Ontology
Complex events
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Plant Sciences
Plant Physiology
Biological and Medical Physics
Biophysics
Cell Biology
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