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Title:
New perspectives of Lactobacillus plantarum as a probiotic: The gut-heart-brain axis | Journal of Microbiology
Description:
Lactobacillus plantarum is a non-gas-producing lactic acid bacterium that is generally regarded as safe (GRAS) with Qualified Presumption of Safety (QPS) status. Although traditionally used for dairy, meat and vegetable fermentation, L. plantarum is gaining increasing significance as a probiotic. With the newly acclaimed gut-heart-brain axis, strains of L. plantarum have proven to be a valuable species for the development of probiotics, with various beneficial effects on gut health, metabolic disorders and brain health. In this review, the classification and taxonomy, and the relation of these with safety aspects are introduced. Characteristics of L. plantarum to fulfill the criteria as a probiotic are discussed. Emphasis are also given to the beneficial functions of L. plantarum in gut disorders such as inflammatory bowel diseases, metabolic syndromes, dyslipidemia, hypercholesteromia, obesity, and diabetes, and brain health aspects involving psychological disorders.
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pubmed, google, scholar, article, cas, lactobacillus, plantarum, central, gut, probiotic, mice, food, microbiol, microbiota, wang, tsai, isolated, disease, kim, health, liu, rev, strains, nat, intestinal, zhang, colitis, park, obesity, microbiome, sci, human, bowel, rats, nature, lee, effects, immunol, inflammation, res, role, biotechnol, world, axis, inflammatory, properties, potential, int, cell, chen,
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int/en/news-room/fact-sheets/detail/diabetes int/mediacentre/factsheets/fs311/en/ int/mediacentre/ factsheets/fs220/en/ month download article/chapter microbiology yen-wenn liu gut-heart-brain axis il6/stat3/socs3 signalling pathway ying-chieh tsai ulcerative colitis-related carcinogenesis brain-gut axis dysfunction min-tze liong cis3/socs3/ssi3 plays diet-induced obese mice brain-derived neurotrophic factor intestinal gram-negative bacteria transforming growth factor-beta national yang-ming university gut-brain axis high-fructose diet lactobacillus plantarum k68 central nervous systems metabolic syndromes obesity-related insulin resistance high-fat diet high fat diet full article pdf naive adult mice health claims related european economic area dextran sulfate sodium lactic acid bacteria inflammatory heart disease lactobacillus plantarum fh185 foxp3+ inducible regulatory lactobacillus plantarum isolated engineering metabolic highways prebiotic inulin alleviates lactobacillus plantarum prevents related subjects c57bl/6 mice fed lactobacillus plantarum strains disease-related expression privacy choices/manage cookies alloxan-induced diabetes regulates fat storage cell-dependent colitis lactobacillus plantarum kctc3928 nanometric lactobacillus plantarum lactobacillus plantarum ccfm0236 lactobacillus plantarum x1
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headline:New perspectives of Lactobacillus plantarum as a probiotic: The gut-heart-brain axis
description:Lactobacillus plantarum is a non-gas-producing lactic acid bacterium that is generally regarded as safe (GRAS) with Qualified Presumption of Safety (QPS) status. Although traditionally used for dairy, meat and vegetable fermentation, L. plantarum is gaining increasing significance as a probiotic. With the newly acclaimed gut-heart-brain axis, strains of L. plantarum have proven to be a valuable species for the development of probiotics, with various beneficial effects on gut health, metabolic disorders and brain health. In this review, the classification and taxonomy, and the relation of these with safety aspects are introduced. Characteristics of L. plantarum to fulfill the criteria as a probiotic are discussed. Emphasis are also given to the beneficial functions of L. plantarum in gut disorders such as inflammatory bowel diseases, metabolic syndromes, dyslipidemia, hypercholesteromia, obesity, and diabetes, and brain health aspects involving psychological disorders.
datePublished:2018-08-23T00:00:00Z
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gut-heart-brain axis
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Microbiology
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Microbiology
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