We are analyzing https://link.springer.com/article/10.1007/s12265-009-9101-1.

Title:
Sexual Dimorphism in Body Fat Distribution and Risk for Cardiovascular Diseases | Journal of Cardiovascular Translational Research
Description:
The prevalence of obesity has dramatically increased over the past decade along with the cardiovascular and other health risks it encompasses. Adipose tissue, which is distributed in the abdominal viscera, carries a greater risk for cardiovascular disorders than adipose tissue subcutaneously. There is a sex difference in the regional fat distribution. Women have more subcutaneous fat, whereas men have more visceral fat. Therefore, obesity-related metabolic disorders are much lower in premenopausal women than men. Peripheral metabolic signals like leptin and insulin are involved in the food intake, body weight, body fat distribution, and cardiovascular disease. Key areas in the brain, including the hypothalamus, integrates these peripheral adiposity signals to maintain overall adiposity levels, and these brain regions are directly influenced by sex hormones. Therefore, differences in cardiovascular disease may be under the influence of sex hormones either directly in the brain or through their influence of body fat distribution. The role of estrogen in mediating body fat distribution and cardiovascular disease is the focus of this review.
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Keywords {🔍}

google, scholar, pubmed, article, cas, obesity, journal, fat, metabolic, leptin, cardiovascular, body, estrogen, distribution, disease, adipose, tissue, medicine, research, clegg, syndrome, diabetes, insulin, system, metabolism, endocrinology, central, clinical, nature, mice, content, risk, diseases, disorders, sex, women, adiposity, differences, related, international, regulation, woods, privacy, cookies, abdominal, men, visceral, weight, brain, review,

Topics {✒️}

month download article/chapter estrogen receptor-alpha gene alpha-melanocyte-stimulating hormone la differe´nciation sexuelle blood institute-national institute obesity-related metabolic disorders central nervous system estrogen receptor alpha cardiovascular diseases published sympathetic nervous system full article pdf sexual dimorphism privacy choices/manage cookies related metabolic disorders body fat distribution body fat distribution adrenergic receptor expression biophysical research communications regional fat distribution fat cell metabolism intra-abdominal adiposity visceral adipose tissue peripheral adiposity signals central leptin insensitivity abdominal fat distribution sex/gender differences increased hypothalamic neuropeptide peripheral metabolic signals cardiovascular diseases fat cell function coronary artery disease european economic area diet-induced resistance disturbed lipoprotein profile estradiol inhibits feeding colonal hypothalamic neurons check access instant access ischaemic heart disease conditions privacy policy serum leptin concentration related subjects social class influences visceral fat adiposity levels sympathetic neural activation nutrition examination survey regulate glucose homeostasis nucleus tractus solitarius research clinical endocrinology

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         description:The prevalence of obesity has dramatically increased over the past decade along with the cardiovascular and other health risks it encompasses. Adipose tissue, which is distributed in the abdominal viscera, carries a greater risk for cardiovascular disorders than adipose tissue subcutaneously. There is a sex difference in the regional fat distribution. Women have more subcutaneous fat, whereas men have more visceral fat. Therefore, obesity-related metabolic disorders are much lower in premenopausal women than men. Peripheral metabolic signals like leptin and insulin are involved in the food intake, body weight, body fat distribution, and cardiovascular disease. Key areas in the brain, including the hypothalamus, integrates these peripheral adiposity signals to maintain overall adiposity levels, and these brain regions are directly influenced by sex hormones. Therefore, differences in cardiovascular disease may be under the influence of sex hormones either directly in the brain or through their influence of body fat distribution. The role of estrogen in mediating body fat distribution and cardiovascular disease is the focus of this review.
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      description:The prevalence of obesity has dramatically increased over the past decade along with the cardiovascular and other health risks it encompasses. Adipose tissue, which is distributed in the abdominal viscera, carries a greater risk for cardiovascular disorders than adipose tissue subcutaneously. There is a sex difference in the regional fat distribution. Women have more subcutaneous fat, whereas men have more visceral fat. Therefore, obesity-related metabolic disorders are much lower in premenopausal women than men. Peripheral metabolic signals like leptin and insulin are involved in the food intake, body weight, body fat distribution, and cardiovascular disease. Key areas in the brain, including the hypothalamus, integrates these peripheral adiposity signals to maintain overall adiposity levels, and these brain regions are directly influenced by sex hormones. Therefore, differences in cardiovascular disease may be under the influence of sex hormones either directly in the brain or through their influence of body fat distribution. The role of estrogen in mediating body fat distribution and cardiovascular disease is the focus of this review.
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         general
         Medicine/Public Health
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