We are analyzing https://link.springer.com/article/10.1007/s12253-018-0541-2.

Title:
Combined Treatment with Autologous CIK Cells, Radiotherapy and Chemotherapy in Advanced Cervical Cancer | Pathology & Oncology Research
Description:
To investigate the clinical efficacy of autologous cytokine induced killer (CIK) cells transfusion combined with radiochemotherapy in the treatment of advanced cervical cancer. A total of 89 hospitalized patients with advanced cervical cancer were admitted and divided into the treatment group (44 cases, autologous CIK cells transfusion combined with radiochemotherapy) and the control group (45 cases, radiochemotherapy) by a randomized non-blind method. Comparisons of therapeutic efficacies, immune functions, life qualities and survival rates were analyzed between the two groups. The short-term therapeutic efficacy of the treatment group was significantly higher than that of the control group. There was no significant difference in 1, 2 and 3 year survival rates between the two groups. Compared with pre-treatment, levels of CD3+, CD4+/CD8+ in peripheral blood were increased in the CIK group, which were reduced in the control group. In the CIK group,only the feeling was depressed on the 25th day post-treatment (T25) compared with the day before treatment (B1). However in the control group, the function of body, role, social and holistic health was obvious disordered on day T25 compared with day B1. On day T25, there were significant differences in function of body, social and holistic health between two groups. Autologous CIK cells transfusion combined with radiochemotherapy shows better short-term efficacy than radiochemotherapy alone in the treatment of advanced cervical cancer, which obviously improves immune function and life quality of patients with low side effects.
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28 years and 1 months (reg. 1997-05-29).

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Keywords {🔍}

cancer, article, cells, cervical, treatment, cik, google, scholar, autologous, pubmed, killer, cas, combined, chemotherapy, advanced, cell, patients, group, cytokineinduced, research, clinical, radiochemotherapy, privacy, cookies, function, content, efficacy, day, immunotherapy, therapy, kaifeng, data, information, publish, search, radiotherapy, liu, transfusion, control, immune, access, med, central, kim, springer, social, log, journal, published, tian,

Topics {✒️}

ling gao & zhi-qiao xu month download article/chapter cytokine-induced killer cells autologous dc-cik cells myeloablative allogeneic transplantation virus-derived 2a sequences dc-cik cells enhances /ii clinical trial donor-derived cik cells wen-jie shen zhi-qiao xu cell immunotherapeutic efficacy immune therapy combined cytokine-induced killer advanced cervical cancer autologous cik cells technology research projects cells transfusion combined 25th day post-treatment short-term therapeutic efficacy invasive cervical cancer iia1 cervical cancer cervical cancer models full article pdf advanced colorectal cancer advanced pancreatic cancer privacy choices/manage cookies kaifeng central hospital low side effects clinical scale expansion dendritic cells infected related subjects short-term efficacy cervical cancer european economic area dan-dan meng cross-sectional study female university students chronic myeloid leukemia targeting opioidergic pathways effective adoptive immunotherapy conditions privacy policy article li ethics declarations conflict accepting optional cookies randomized controlled trials additional information publisher article log yong-wei tian therapy

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         headline:Combined Treatment with Autologous CIK Cells, Radiotherapy and Chemotherapy in Advanced Cervical Cancer
         description:To investigate the clinical efficacy of autologous cytokine induced killer (CIK) cells transfusion combined with radiochemotherapy in the treatment of advanced cervical cancer. A total of 89 hospitalized patients with advanced cervical cancer were admitted and divided into the treatment group (44 cases, autologous CIK cells transfusion combined with radiochemotherapy) and the control group (45 cases, radiochemotherapy) by a randomized non-blind method. Comparisons of therapeutic efficacies, immune functions, life qualities and survival rates were analyzed between the two groups. The short-term therapeutic efficacy of the treatment group was significantly higher than that of the control group. There was no significant difference in 1, 2 and 3 year survival rates between the two groups. Compared with pre-treatment, levels of CD3+, CD4+/CD8+ in peripheral blood were increased in the CIK group, which were reduced in the control group. In the CIK group,only the feeling was depressed on the 25th day post-treatment (T25) compared with the day before treatment (B1). However in the control group, the function of body, role, social and holistic health was obvious disordered on day T25 compared with day B1. On day T25, there were significant differences in function of body, social and holistic health between two groups. Autologous CIK cells transfusion combined with radiochemotherapy shows better short-term efficacy than radiochemotherapy alone in the treatment of advanced cervical cancer, which obviously improves immune function and life quality of patients with low side effects.
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      description:To investigate the clinical efficacy of autologous cytokine induced killer (CIK) cells transfusion combined with radiochemotherapy in the treatment of advanced cervical cancer. A total of 89 hospitalized patients with advanced cervical cancer were admitted and divided into the treatment group (44 cases, autologous CIK cells transfusion combined with radiochemotherapy) and the control group (45 cases, radiochemotherapy) by a randomized non-blind method. Comparisons of therapeutic efficacies, immune functions, life qualities and survival rates were analyzed between the two groups. The short-term therapeutic efficacy of the treatment group was significantly higher than that of the control group. There was no significant difference in 1, 2 and 3 year survival rates between the two groups. Compared with pre-treatment, levels of CD3+, CD4+/CD8+ in peripheral blood were increased in the CIK group, which were reduced in the control group. In the CIK group,only the feeling was depressed on the 25th day post-treatment (T25) compared with the day before treatment (B1). However in the control group, the function of body, role, social and holistic health was obvious disordered on day T25 compared with day B1. On day T25, there were significant differences in function of body, social and holistic health between two groups. Autologous CIK cells transfusion combined with radiochemotherapy shows better short-term efficacy than radiochemotherapy alone in the treatment of advanced cervical cancer, which obviously improves immune function and life quality of patients with low side effects.
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