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         headline:The Baseline Ratio of Neutrophils to Lymphocytes is Associated with Patient Prognosis in Rectal Carcinoma
         description:In cancer patients, the balance between neutrophil (N) and lymphocyte (L) cell counts fluctuates with advancing disease. The objective of our study was to determine the prognostic implications of the N/L ratio in the peripheral blood of rectal cancer patients. Study participants were identified from a prospective cohort of patients with rectal cancer in Dalian of China (n = 123). The median baseline N/L ratio was 2.41 ± 2.206 (range, 0.76–20.45). Our results revealed that the N/L ratio was significantly associated with tumor size (P = 0.003) and level of cancer antigen 125 (P = 0.027). A multivariate Cox model established a significant relationship between the N/L ratio and survival (adjusted hazard ratio, 2.615; 95% confidence interval, 1.152–5.933; P = 0.021). These results suggest that the N/L ratio is an independent prognostic factor in rectal cancer, and the N/L ratio may serve as a clinically accessible and useful biomarker for patient survival.
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      headline:The Baseline Ratio of Neutrophils to Lymphocytes is Associated with Patient Prognosis in Rectal Carcinoma
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         Radiotherapy
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         Internal Medicine
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