We are analyzing https://link.springer.com/article/10.1007/s12016-010-8197-z.

Title:
Urinary Biomarkers in Lupus Nephritis | Clinical Reviews in Allergy & Immunology
Description:
Renal involvement in patients with systemic lupus erythematosus in the form of severe lupus nephritis is associated with a significant burden of morbidity and mortality. Conventional laboratory biomarkers in current use have not been very successful in anticipating disease flares, predicting renal histology, or decreasing unwanted outcomes. Since early treatment is associated with improved clinical results, it is thus essential to identify new biomarkers with substantial predictive power to reduce the serious sequelae of this difficult to control lupus manifestation. Indeed, considerable efforts and progress have been made over the last few years in the search for novel biomarkers. Since urinary biomarkers are more easily obtainable with much less risk to the patient than repeat renal biopsies, and these may more accurately discern between renal disease and other organ manifestations than their serum counterparts, there has been tremendous interest in studying new candidate urine biomarkers. Below, we review several promising urinary biomarkers under investigation, including total proteinuria and microalbuminuria, urinary proteomic signatures, and the individual inflammatory mediators interleukin-6, vascular cell adhesion molecule-1, CXCL16, IP-10, and tumor necrosis factor-like weak inducer of apoptosis.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Health & Fitness
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Link.springer.com might have a hidden revenue stream, but it's not something we can detect.

Keywords {🔍}

google, scholar, pubmed, article, cas, lupus, nephritis, biomarkers, urinary, systemic, erythematosus, renal, urine, rheumatol, kidney, immunol, disease, tweak, patients, proteinuria, protein, cell, nephrol, activity, clin, arthritis, chemokine, rheum, cells, ligand, putterman, int, human, expression, burkly, clinical, adhesion, active, med, study, rovin, factor, privacy, cookies, content, search, serum, interleukin, access, markers,

Topics {✒️}

surface-enhanced laser-desorption/ionization time chronic graft-versus-host model chronic graft-versus-host disease mrl/lpr lupus-prone mice month download article/chapter irene blanco & chaim putterman anti-dna antibody production ifn-inducible protein-10 relating leukemia inhibitory factor/oncostatin induces cell-cell adhesion article reyes-thomas article clinical reviews systemic lupus erythematosus-relationship sr-psox cell surface expression full article pdf systemic lupus erythematosus mrl/lpr mice sle renal activity gomez-lechon mj privacy choices/manage cookies interferon-inducible protein 10 serial urine proteomics urinary protein markers de azevedo vf modulates fibroblast adhesion active lupus nephritis prognostic factors urine biomarkers predict tumor necrosis factor collaborative study group anticipating disease flares pristane-induced lupus candidate urine biomarkers promising urinary biomarkers urinary biomarkers discriminates candidate urinary biomarkers lupus nephritis published severe lupus nephritis lupus nephritis determined subclinical lupus nephritis inactive lupus nephritis murine lupus nephritis substantial predictive power related subjects urinary albumin excretion excreted urinary mediators soluble tnf receptor-1 national kidney foundation antiendothelial cell antibodies

Questions {❓}

Esdaile JM, Joseph L, Abrahamowicz M, Li Y, Danoff D, Clarke AE (1996) Routine immunologic tests in systemic lupus erythematosus: is there a need for more studies?
Moroni G, Radice A, Giammarresi G et al (2009) Are laboratory tests useful for monitoring the activity of lupus nephritis?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Urinary Biomarkers in Lupus Nephritis
         description:Renal involvement in patients with systemic lupus erythematosus in the form of severe lupus nephritis is associated with a significant burden of morbidity and mortality. Conventional laboratory biomarkers in current use have not been very successful in anticipating disease flares, predicting renal histology, or decreasing unwanted outcomes. Since early treatment is associated with improved clinical results, it is thus essential to identify new biomarkers with substantial predictive power to reduce the serious sequelae of this difficult to control lupus manifestation. Indeed, considerable efforts and progress have been made over the last few years in the search for novel biomarkers. Since urinary biomarkers are more easily obtainable with much less risk to the patient than repeat renal biopsies, and these may more accurately discern between renal disease and other organ manifestations than their serum counterparts, there has been tremendous interest in studying new candidate urine biomarkers. Below, we review several promising urinary biomarkers under investigation, including total proteinuria and microalbuminuria, urinary proteomic signatures, and the individual inflammatory mediators interleukin-6, vascular cell adhesion molecule-1, CXCL16, IP-10, and tumor necrosis factor-like weak inducer of apoptosis.
         datePublished:2010-02-02T00:00:00Z
         dateModified:2010-02-02T00:00:00Z
         pageStart:138
         pageEnd:150
         sameAs:https://doi.org/10.1007/s12016-010-8197-z
         keywords:
            Biomarkers
            Lupus nephritis
            Urinary biomarkers
            Proteomics
            TWEAK
            SLE
            Allergology
            Immunology
            Internal Medicine
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12016-010-8197-z/MediaObjects/12016_2010_8197_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12016-010-8197-z/MediaObjects/12016_2010_8197_Fig2_HTML.gif
         isPartOf:
            name:Clinical Reviews in Allergy & Immunology
            issn:
               1559-0267
               1080-0549
            volumeNumber:40
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Humana Press Inc
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Joyce Reyes-Thomas
               affiliation:
                     name:Albert Einstein College of Medicine
                     address:
                        name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Irene Blanco
               affiliation:
                     name:Albert Einstein College of Medicine
                     address:
                        name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Chaim Putterman
               affiliation:
                     name:Albert Einstein College of Medicine
                     address:
                        name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Urinary Biomarkers in Lupus Nephritis
      description:Renal involvement in patients with systemic lupus erythematosus in the form of severe lupus nephritis is associated with a significant burden of morbidity and mortality. Conventional laboratory biomarkers in current use have not been very successful in anticipating disease flares, predicting renal histology, or decreasing unwanted outcomes. Since early treatment is associated with improved clinical results, it is thus essential to identify new biomarkers with substantial predictive power to reduce the serious sequelae of this difficult to control lupus manifestation. Indeed, considerable efforts and progress have been made over the last few years in the search for novel biomarkers. Since urinary biomarkers are more easily obtainable with much less risk to the patient than repeat renal biopsies, and these may more accurately discern between renal disease and other organ manifestations than their serum counterparts, there has been tremendous interest in studying new candidate urine biomarkers. Below, we review several promising urinary biomarkers under investigation, including total proteinuria and microalbuminuria, urinary proteomic signatures, and the individual inflammatory mediators interleukin-6, vascular cell adhesion molecule-1, CXCL16, IP-10, and tumor necrosis factor-like weak inducer of apoptosis.
      datePublished:2010-02-02T00:00:00Z
      dateModified:2010-02-02T00:00:00Z
      pageStart:138
      pageEnd:150
      sameAs:https://doi.org/10.1007/s12016-010-8197-z
      keywords:
         Biomarkers
         Lupus nephritis
         Urinary biomarkers
         Proteomics
         TWEAK
         SLE
         Allergology
         Immunology
         Internal Medicine
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12016-010-8197-z/MediaObjects/12016_2010_8197_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12016-010-8197-z/MediaObjects/12016_2010_8197_Fig2_HTML.gif
      isPartOf:
         name:Clinical Reviews in Allergy & Immunology
         issn:
            1559-0267
            1080-0549
         volumeNumber:40
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Humana Press Inc
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Joyce Reyes-Thomas
            affiliation:
                  name:Albert Einstein College of Medicine
                  address:
                     name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Irene Blanco
            affiliation:
                  name:Albert Einstein College of Medicine
                  address:
                     name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Chaim Putterman
            affiliation:
                  name:Albert Einstein College of Medicine
                  address:
                     name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Clinical Reviews in Allergy & Immunology
      issn:
         1559-0267
         1080-0549
      volumeNumber:40
Organization:
      name:Humana Press Inc
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Albert Einstein College of Medicine
      address:
         name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
         type:PostalAddress
      name:Albert Einstein College of Medicine
      address:
         name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
         type:PostalAddress
      name:Albert Einstein College of Medicine
      address:
         name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Joyce Reyes-Thomas
      affiliation:
            name:Albert Einstein College of Medicine
            address:
               name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
               type:PostalAddress
            type:Organization
      name:Irene Blanco
      affiliation:
            name:Albert Einstein College of Medicine
            address:
               name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
               type:PostalAddress
            type:Organization
      name:Chaim Putterman
      affiliation:
            name:Albert Einstein College of Medicine
            address:
               name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
      name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
      name:Division of Rheumatology, Albert Einstein College of Medicine, New York, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(270)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

5.08s.

LINK . SPRINGER . COM {}