We are analyzing https://link.springer.com/article/10.1007/s12016-009-8190-6.

Title:
Pregnancy Outcomes in Patients with Autoimmune Diseases and Anti-Ro/SSA Antibodies | Clinical Reviews in Allergy & Immunology
Description:
Anti-Ro/SSA antibodies are associated with neonatal lupus (congenital heart block (CHB), neonatal transient skin rash, hematological and hepatic abnormalities), but do not negatively affects other gestational outcomes, and the general outcome of these pregnancies is now good, when followed by experienced multidisciplinary teams. The prevalence of CHB, defined as an atrioventricular block diagnosed in utero, at birth, or within the neonatal period (0–27 days after birth), in the offspring of an anti-Ro/SSA-positive women is 1–2%, of neonatal lupus rash around 10–20%, while laboratory abnormalities in asymptomatic babies can be detected in up to 27% of cases. The risk of recurrence of CHB is ten times higher. Most of the mothers are asymptomatic at delivery and are identified only by the birth of an affected child. Half of these asymptomatic women develop symptoms of a rheumatic disease, most commonly arthralgias and xerophtalmia, but few develop lupus nephritis. A standard therapy for CHB is still matter of investigation, although fluorinated corticosteroids have been reported to be effective for associated cardiomyopathy. Serial echocardiograms and obstetric sonograms, performed at least every 1–2 weeks starting from the 16th week of gestational age, are recommended in anti-Ro/SSA-positive pregnant women to detect early fetal abnormalities that might be a target of preventive therapy.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Health & Fitness
Social Networks

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,016 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure how the site profits.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Link.springer.com has a revenue plan, but it's either invisible or we haven't found it.

Keywords {🔍}

google, scholar, pubmed, cas, block, heart, congenital, lupus, antibodies, rheum, neonatal, arthritis, brucato, outcome, buyon, mothers, fetal, complete, study, children, atrioventricular, erythematosus, rheumatol, article, antirossa, cimaz, women, maternal, factor, autoimmune, disease, obstet, risk, therapy, antiro, isolated, circulation, cardiol, gynecol, pregnancy, abnormalities, prospective, clin, silverman, autoantibodies, syndrome, immunol, julkunen, longterm, diseases,

Topics {✒️}

maternal anti-ssa/ro-ssb/la antibodies anti-ssa/ro-ssb/la antibodies anti-ro/ssa-positive pregnant women anti-la antibody profiles anti-ro/ssa antibodies published anti-ssa/ro 52-kd antibodies anti-ssb/la autoantibodies bind anti-ro/ssa-positive women anti-ro/ssa-positive patients anti-ro/ssa antibodies detected anti-ro/la-positive cases anti-ro/la antibodies comparison anti-ro/ssa antibodies anti-ssa/ro antibodies month download article/chapter tumor necrosis factor-alpha develop lupus nephritis anti-ro/la antibodies t-type calcium channels maternal anti-ro antibodies enzyme-linked immunosorbent assay native 60-kd ro/ss denatured 52-kd ro/ss bleomycin-induced pulmonary fibrosis anti-ro/ssa anti-ssa/ro la/ssb antibodies systemic lupus erythematosus fetal kinetocardiogram-based study anti-ro antibodies tumor necrosis factor ssb/la antigens anti-la antibodies congenital heart block complete heart block atrioventricular block diagnosed systemic lupus erytematosus rheumatic disease neonatal lupus erythematosus article clinical reviews retrospective cohort study antonio brucato maternal anti-ro cutaneous lupus erythematosus anti-ro autoantibodies ten times higher privacy choices/manage cookies fetal heart block anti-52 kda ro anti-60 kda ro

Questions {❓}

Buyon JP, Brucato A, Friedman DM (2008) What's in a name?
Cimaz R (2004) Any increased risk of autoimmune disease?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Pregnancy Outcomes in Patients with Autoimmune Diseases and Anti-Ro/SSA Antibodies
         description:Anti-Ro/SSA antibodies are associated with neonatal lupus (congenital heart block (CHB), neonatal transient skin rash, hematological and hepatic abnormalities), but do not negatively affects other gestational outcomes, and the general outcome of these pregnancies is now good, when followed by experienced multidisciplinary teams. The prevalence of CHB, defined as an atrioventricular block diagnosed in utero, at birth, or within the neonatal period (0–27 days after birth), in the offspring of an anti-Ro/SSA-positive women is 1–2%, of neonatal lupus rash around 10–20%, while laboratory abnormalities in asymptomatic babies can be detected in up to 27% of cases. The risk of recurrence of CHB is ten times higher. Most of the mothers are asymptomatic at delivery and are identified only by the birth of an affected child. Half of these asymptomatic women develop symptoms of a rheumatic disease, most commonly arthralgias and xerophtalmia, but few develop lupus nephritis. A standard therapy for CHB is still matter of investigation, although fluorinated corticosteroids have been reported to be effective for associated cardiomyopathy. Serial echocardiograms and obstetric sonograms, performed at least every 1–2 weeks starting from the 16th week of gestational age, are recommended in anti-Ro/SSA-positive pregnant women to detect early fetal abnormalities that might be a target of preventive therapy.
         datePublished:2009-12-11T00:00:00Z
         dateModified:2009-12-11T00:00:00Z
         pageStart:27
         pageEnd:41
         sameAs:https://doi.org/10.1007/s12016-009-8190-6
         keywords:
            Heart block/congenital
            Neonatal lupus
            Anti-Ro/SSA antibodies
            Allergology
            Immunology
            Internal Medicine
         image:
         isPartOf:
            name:Clinical Reviews in Allergy & Immunology
            issn:
               1559-0267
               1080-0549
            volumeNumber:40
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Humana Press Inc
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Antonio Brucato
               affiliation:
                     name:Internal Medicine
                     address:
                        name:Internal Medicine, Bergamo, Italy
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Rolando Cimaz
               affiliation:
                     name:Meyer Children’s Hospital and University of Florence
                     address:
                        name:Meyer Children’s Hospital and University of Florence, Florence, Italy
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Roberto Caporali
               affiliation:
                     name:University and IRCCS Policlinico San Matteo Foundation
                     address:
                        name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Véronique Ramoni
               affiliation:
                     name:Internal Medicine
                     address:
                        name:Internal Medicine, Bergamo, Italy
                        type:PostalAddress
                     type:Organization
                     name:University and IRCCS Policlinico San Matteo Foundation
                     address:
                        name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jill Buyon
               affiliation:
                     name:New York University School of Medicine
                     address:
                        name:New York University School of Medicine, New York, USA
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Pregnancy Outcomes in Patients with Autoimmune Diseases and Anti-Ro/SSA Antibodies
      description:Anti-Ro/SSA antibodies are associated with neonatal lupus (congenital heart block (CHB), neonatal transient skin rash, hematological and hepatic abnormalities), but do not negatively affects other gestational outcomes, and the general outcome of these pregnancies is now good, when followed by experienced multidisciplinary teams. The prevalence of CHB, defined as an atrioventricular block diagnosed in utero, at birth, or within the neonatal period (0–27 days after birth), in the offspring of an anti-Ro/SSA-positive women is 1–2%, of neonatal lupus rash around 10–20%, while laboratory abnormalities in asymptomatic babies can be detected in up to 27% of cases. The risk of recurrence of CHB is ten times higher. Most of the mothers are asymptomatic at delivery and are identified only by the birth of an affected child. Half of these asymptomatic women develop symptoms of a rheumatic disease, most commonly arthralgias and xerophtalmia, but few develop lupus nephritis. A standard therapy for CHB is still matter of investigation, although fluorinated corticosteroids have been reported to be effective for associated cardiomyopathy. Serial echocardiograms and obstetric sonograms, performed at least every 1–2 weeks starting from the 16th week of gestational age, are recommended in anti-Ro/SSA-positive pregnant women to detect early fetal abnormalities that might be a target of preventive therapy.
      datePublished:2009-12-11T00:00:00Z
      dateModified:2009-12-11T00:00:00Z
      pageStart:27
      pageEnd:41
      sameAs:https://doi.org/10.1007/s12016-009-8190-6
      keywords:
         Heart block/congenital
         Neonatal lupus
         Anti-Ro/SSA antibodies
         Allergology
         Immunology
         Internal Medicine
      image:
      isPartOf:
         name:Clinical Reviews in Allergy & Immunology
         issn:
            1559-0267
            1080-0549
         volumeNumber:40
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Humana Press Inc
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Antonio Brucato
            affiliation:
                  name:Internal Medicine
                  address:
                     name:Internal Medicine, Bergamo, Italy
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Rolando Cimaz
            affiliation:
                  name:Meyer Children’s Hospital and University of Florence
                  address:
                     name:Meyer Children’s Hospital and University of Florence, Florence, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Roberto Caporali
            affiliation:
                  name:University and IRCCS Policlinico San Matteo Foundation
                  address:
                     name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Véronique Ramoni
            affiliation:
                  name:Internal Medicine
                  address:
                     name:Internal Medicine, Bergamo, Italy
                     type:PostalAddress
                  type:Organization
                  name:University and IRCCS Policlinico San Matteo Foundation
                  address:
                     name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jill Buyon
            affiliation:
                  name:New York University School of Medicine
                  address:
                     name:New York University School of Medicine, New York, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Clinical Reviews in Allergy & Immunology
      issn:
         1559-0267
         1080-0549
      volumeNumber:40
Organization:
      name:Humana Press Inc
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Internal Medicine
      address:
         name:Internal Medicine, Bergamo, Italy
         type:PostalAddress
      name:Meyer Children’s Hospital and University of Florence
      address:
         name:Meyer Children’s Hospital and University of Florence, Florence, Italy
         type:PostalAddress
      name:University and IRCCS Policlinico San Matteo Foundation
      address:
         name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
         type:PostalAddress
      name:Internal Medicine
      address:
         name:Internal Medicine, Bergamo, Italy
         type:PostalAddress
      name:University and IRCCS Policlinico San Matteo Foundation
      address:
         name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
         type:PostalAddress
      name:New York University School of Medicine
      address:
         name:New York University School of Medicine, New York, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Antonio Brucato
      affiliation:
            name:Internal Medicine
            address:
               name:Internal Medicine, Bergamo, Italy
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Rolando Cimaz
      affiliation:
            name:Meyer Children’s Hospital and University of Florence
            address:
               name:Meyer Children’s Hospital and University of Florence, Florence, Italy
               type:PostalAddress
            type:Organization
      name:Roberto Caporali
      affiliation:
            name:University and IRCCS Policlinico San Matteo Foundation
            address:
               name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
               type:PostalAddress
            type:Organization
      name:Véronique Ramoni
      affiliation:
            name:Internal Medicine
            address:
               name:Internal Medicine, Bergamo, Italy
               type:PostalAddress
            type:Organization
            name:University and IRCCS Policlinico San Matteo Foundation
            address:
               name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
               type:PostalAddress
            type:Organization
      name:Jill Buyon
      affiliation:
            name:New York University School of Medicine
            address:
               name:New York University School of Medicine, New York, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Internal Medicine, Bergamo, Italy
      name:Meyer Children’s Hospital and University of Florence, Florence, Italy
      name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
      name:Internal Medicine, Bergamo, Italy
      name:Division of Rheumatology, University and IRCCS Policlinico San Matteo Foundation, Pavia, Italy
      name:New York University School of Medicine, New York, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(253)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.71s.

LINK . SPRINGER . COM {}