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Title:
Chronic Granulomatous Disease | Clinical Reviews in Allergy & Immunology
Description:
Chronic granulomatous disease (CGD) was first described in the 1950s and has become a paradigm for genetic neutrophil diseases. It is characterized by recurrent infections with a narrow spectrum of bacteria and fungi as well as a common set of inflammatory complications most notably including inflammatory bowel disease. Over the last half century major advances in management have profoundly altered the major clinical issues and the life expectancy of CGD. With X-linked and autosomal recessive forms, it has been an important disease for the development of bone marrow transplantation and gene therapy. Some of the recent developments in infectious syndromes, inflammatory complications, and curative approaches are discussed in this review.
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disease, google, scholar, chronic, granulomatous, pubmed, article, cas, holland, gallin, malech, clin, dis, cgd, infect, clinical, segal, patients, inflammatory, xlinked, therapy, infection, decarlo, anderson, pediatr, infections, med, nadph, immunol, privacy, cookies, content, transplantation, gene, access, child, kleiner, miller, treatment, aspergillus, publish, research, search, allergy, neutrophil, review, features, report, seger, hilligoss,
Topics {βοΈ}
t-cell-depleted hematopoietic allograft month download article/chapter nadph oxidase-corrected granulocytes long-term interferon-gamma therapy alcohol-induced liver disease glucose-6-phosphate dehydrogenase volendam inflammatory bowel disease related subjects good long-term outcome severe combined immunodeficiency article clinical reviews full article pdf chronic granulomatous disease age-related skewing italian multicenter study privacy choices/manage cookies fatal granulomatous disease x-linked cgd functional nadph oxidase long-term follow lung transplantation center discoid lupus erythematosus bone marrow transplantation neutrophil disorders unmodified hemopoietic allograft chronic nonspherocytic anemia infectious syndromes x-linked lupus erythematosus tumidus granulibacter bethesdensis isolated major clinical issues autosomal recessive forms trimethoprim-sulfamethoxazole prophylaxis francisella philomiragia adenitis kwon-chung kj parrilla-castellar er fulminant mulch pneumonitis thymic granulomas due complete myeloperoxidase deficiency pronk-admiraal cj damage aspergillus hyphae reactive oxygen species atherosclerotic lesion progression synaptic plasticity deficits mild memory impairments chronic inflammation crohn' van noorden cj van der merwe paecilomyces varioti infection aspergillus nidulans infection
Questions {β}
- Cavazzana-Calvo M, Fischer A (2007) Gene therapy for severe combined immunodeficiency: are we there yet?
Schema {πΊοΈ}
WebPage:
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headline:Chronic Granulomatous Disease
description:Chronic granulomatous disease (CGD) was first described in the 1950s and has become a paradigm for genetic neutrophil diseases. It is characterized by recurrent infections with a narrow spectrum of bacteria and fungi as well as a common set of inflammatory complications most notably including inflammatory bowel disease. Over the last half century major advances in management have profoundly altered the major clinical issues and the life expectancy of CGD. With X-linked and autosomal recessive forms, it has been an important disease for the development of bone marrow transplantation and gene therapy. Some of the recent developments in infectious syndromes, inflammatory complications, and curative approaches are discussed in this review.
datePublished:2009-06-09T00:00:00Z
dateModified:2009-06-09T00:00:00Z
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pageEnd:10
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Chronic granulomatous disease (CGD)
X-linked disease
NADPH oxidase
Nitroblue tetrazolium (NBT)
Dihydrorhodamine oxidation (DHR)
Aspergillus
Granulibacter
Burkholderia
Allergology
Immunology
Internal Medicine
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headline:Chronic Granulomatous Disease
description:Chronic granulomatous disease (CGD) was first described in the 1950s and has become a paradigm for genetic neutrophil diseases. It is characterized by recurrent infections with a narrow spectrum of bacteria and fungi as well as a common set of inflammatory complications most notably including inflammatory bowel disease. Over the last half century major advances in management have profoundly altered the major clinical issues and the life expectancy of CGD. With X-linked and autosomal recessive forms, it has been an important disease for the development of bone marrow transplantation and gene therapy. Some of the recent developments in infectious syndromes, inflammatory complications, and curative approaches are discussed in this review.
datePublished:2009-06-09T00:00:00Z
dateModified:2009-06-09T00:00:00Z
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Chronic granulomatous disease (CGD)
X-linked disease
NADPH oxidase
Nitroblue tetrazolium (NBT)
Dihydrorhodamine oxidation (DHR)
Aspergillus
Granulibacter
Burkholderia
Allergology
Immunology
Internal Medicine
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