We are analyzing https://link.springer.com/article/10.1007/s12011-007-8062-y.

Title:
Copper, Chromium, Manganese, Iron, Nickel, and Zinc Levels in Biological Samples of Diabetes Mellitus Patients | Biological Trace Element Research
Description:
There is accumulating evidence that the metabolism of several trace elements is altered in diabetes mellitus and that these nutrients might have specific roles in the pathogenesis and progress of this disease. The aim of present study was to compare the level of essential trace elements, chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), and zinc (Zn) in biological samples (whole blood, urine, and scalp hair) of patients who have diabetes mellitus type 2 (n = 257), with those of nondiabetic control subjects (n = 166), age ranged (45–75) of both genders. The element concentrations were measured by means of an atomic absorption spectrophotometer after microwave-induced acid digestion. The validity and accuracy was checked by conventional wet-acid-digestion method and using certified reference materials. The overall recoveries of all elements were found in the range of (97.60–99.49%) of certified values. The results of this study showed that the mean values of Zn, Mn, and Cr were significantly reduced in blood and scalp-hair samples of diabetic patients as compared to control subjects of both genders (p < 0.001). The urinary levels of these elements were found to be higher in the diabetic patients than in the age-matched healthy controls. In contrast, high mean values of Cu and Fe were detected in scalp hair and blood from patients versus the nondiabetic subjects, but the differences found in blood samples was not significant (p < 0.05). These results are consistent with those obtained in other studies, confirming that deficiency and efficiency of some essential trace metals may play a role in the development of diabetes mellitus.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Health & Fitness
Education
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We can't see how the site brings in money.

Not every website is profit-driven; some are created to spread information or serve as an online presence. Websites can be made for many reasons. This could be one of them. Link.springer.com might be earning cash quietly, but we haven't detected the monetization method.

Keywords {🔍}

google, scholar, article, diabetes, cas, pubmed, trace, patients, elements, type, mellitus, kazi, chromium, zinc, diabetic, samples, blood, hair, nutr, disease, elem, essential, iron, levels, subjects, res, biol, med, research, biological, copper, afridi, glucose, insulin, clin, privacy, cookies, content, element, manganese, khan, metabolism, study, scalp, values, healthy, metals, access, analysis, publish,

Topics {✒️}

conventional wet-acid-digestion method month download article/chapter ultrasound-assisted acid leaching microwave-induced acid digestion microwave-assisted sample prepa high-ferritin type-2 diabetes anti-diabetic medicinal plants noninsulin-dependent diabetes mellitus streptozotocin-induced diabetic rats age-matched healthy controls full article pdf insulin-dependent diabetes mellitus tasneem gul kazi privacy choices/manage cookies apparently healthy women type-1 diabetes mellitus type-2 diabetes mellitus age-related decreases microwave digestion methods selected medicinal plants slows carbohydrate absorption essential trace elements essential trace metals conditions privacy policy sample preparation techniques hassan imran afridi atomic absorption spectrophotometer pancreatic protein synthesis body iron stores global micronutrient deficiencies elevated iron indices cross sectional survey left ventricular systolic low density lipoprotein baldor lc jcr-la corpulent ramana murty gav diabetes mellitus patients chronic renal failure isr med assoc biological samples article kazi check access instant access european economic area mohammad bilal arain certified reference materials urban school boys macular degeneration patients β-cell function

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Copper, Chromium, Manganese, Iron, Nickel, and Zinc Levels in Biological Samples of Diabetes Mellitus Patients
         description:There is accumulating evidence that the metabolism of several trace elements is altered in diabetes mellitus and that these nutrients might have specific roles in the pathogenesis and progress of this disease. The aim of present study was to compare the level of essential trace elements, chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), and zinc (Zn) in biological samples (whole blood, urine, and scalp hair) of patients who have diabetes mellitus type 2 (n = 257), with those of nondiabetic control subjects (n = 166), age ranged (45–75) of both genders. The element concentrations were measured by means of an atomic absorption spectrophotometer after microwave-induced acid digestion. The validity and accuracy was checked by conventional wet-acid-digestion method and using certified reference materials. The overall recoveries of all elements were found in the range of (97.60–99.49%) of certified values. The results of this study showed that the mean values of Zn, Mn, and Cr were significantly reduced in blood and scalp-hair samples of diabetic patients as compared to control subjects of both genders (p < 0.001). The urinary levels of these elements were found to be higher in the diabetic patients than in the age-matched healthy controls. In contrast, high mean values of Cu and Fe were detected in scalp hair and blood from patients versus the nondiabetic subjects, but the differences found in blood samples was not significant (p < 0.05). These results are consistent with those obtained in other studies, confirming that deficiency and efficiency of some essential trace metals may play a role in the development of diabetes mellitus.
         datePublished:2008-01-11T00:00:00Z
         dateModified:2008-01-11T00:00:00Z
         pageStart:1
         pageEnd:18
         sameAs:https://doi.org/10.1007/s12011-007-8062-y
         keywords:
            Biological samples
            Diabetes mellitus
            Essential elements
            Age groups
            Genders
            Biochemistry
            general
            Biotechnology
            Nutrition
            Oncology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-007-8062-y/MediaObjects/12011_2007_8062_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-007-8062-y/MediaObjects/12011_2007_8062_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-007-8062-y/MediaObjects/12011_2007_8062_Fig3_HTML.gif
         isPartOf:
            name:Biological Trace Element Research
            issn:
               1559-0720
               0163-4984
            volumeNumber:122
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Humana Press Inc
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Tasneem Gul Kazi
               affiliation:
                     name:Sindh University
                     address:
                        name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Hassan Imran Afridi
               affiliation:
                     name:Sindh University
                     address:
                        name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Naveed Kazi
               affiliation:
                     name:Liaqut University of Medical and Health Sciences
                     address:
                        name:Liaqut University of Medical and Health Sciences, Jamshoro, Pakistan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mohammad Khan Jamali
               affiliation:
                     name:Sindh University
                     address:
                        name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mohammad Bilal Arain
               affiliation:
                     name:Sindh University
                     address:
                        name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Nussarat Jalbani
               affiliation:
                     name:Sindh University
                     address:
                        name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ghulam Abbas Kandhro
               affiliation:
                     name:Sindh University
                     address:
                        name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Copper, Chromium, Manganese, Iron, Nickel, and Zinc Levels in Biological Samples of Diabetes Mellitus Patients
      description:There is accumulating evidence that the metabolism of several trace elements is altered in diabetes mellitus and that these nutrients might have specific roles in the pathogenesis and progress of this disease. The aim of present study was to compare the level of essential trace elements, chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), and zinc (Zn) in biological samples (whole blood, urine, and scalp hair) of patients who have diabetes mellitus type 2 (n = 257), with those of nondiabetic control subjects (n = 166), age ranged (45–75) of both genders. The element concentrations were measured by means of an atomic absorption spectrophotometer after microwave-induced acid digestion. The validity and accuracy was checked by conventional wet-acid-digestion method and using certified reference materials. The overall recoveries of all elements were found in the range of (97.60–99.49%) of certified values. The results of this study showed that the mean values of Zn, Mn, and Cr were significantly reduced in blood and scalp-hair samples of diabetic patients as compared to control subjects of both genders (p < 0.001). The urinary levels of these elements were found to be higher in the diabetic patients than in the age-matched healthy controls. In contrast, high mean values of Cu and Fe were detected in scalp hair and blood from patients versus the nondiabetic subjects, but the differences found in blood samples was not significant (p < 0.05). These results are consistent with those obtained in other studies, confirming that deficiency and efficiency of some essential trace metals may play a role in the development of diabetes mellitus.
      datePublished:2008-01-11T00:00:00Z
      dateModified:2008-01-11T00:00:00Z
      pageStart:1
      pageEnd:18
      sameAs:https://doi.org/10.1007/s12011-007-8062-y
      keywords:
         Biological samples
         Diabetes mellitus
         Essential elements
         Age groups
         Genders
         Biochemistry
         general
         Biotechnology
         Nutrition
         Oncology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-007-8062-y/MediaObjects/12011_2007_8062_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-007-8062-y/MediaObjects/12011_2007_8062_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs12011-007-8062-y/MediaObjects/12011_2007_8062_Fig3_HTML.gif
      isPartOf:
         name:Biological Trace Element Research
         issn:
            1559-0720
            0163-4984
         volumeNumber:122
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Humana Press Inc
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Tasneem Gul Kazi
            affiliation:
                  name:Sindh University
                  address:
                     name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Hassan Imran Afridi
            affiliation:
                  name:Sindh University
                  address:
                     name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Naveed Kazi
            affiliation:
                  name:Liaqut University of Medical and Health Sciences
                  address:
                     name:Liaqut University of Medical and Health Sciences, Jamshoro, Pakistan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mohammad Khan Jamali
            affiliation:
                  name:Sindh University
                  address:
                     name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mohammad Bilal Arain
            affiliation:
                  name:Sindh University
                  address:
                     name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Nussarat Jalbani
            affiliation:
                  name:Sindh University
                  address:
                     name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ghulam Abbas Kandhro
            affiliation:
                  name:Sindh University
                  address:
                     name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Biological Trace Element Research
      issn:
         1559-0720
         0163-4984
      volumeNumber:122
Organization:
      name:Humana Press Inc
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Sindh University
      address:
         name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
         type:PostalAddress
      name:Sindh University
      address:
         name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
         type:PostalAddress
      name:Liaqut University of Medical and Health Sciences
      address:
         name:Liaqut University of Medical and Health Sciences, Jamshoro, Pakistan
         type:PostalAddress
      name:Sindh University
      address:
         name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
         type:PostalAddress
      name:Sindh University
      address:
         name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
         type:PostalAddress
      name:Sindh University
      address:
         name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
         type:PostalAddress
      name:Sindh University
      address:
         name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Tasneem Gul Kazi
      affiliation:
            name:Sindh University
            address:
               name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Hassan Imran Afridi
      affiliation:
            name:Sindh University
            address:
               name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
               type:PostalAddress
            type:Organization
      name:Naveed Kazi
      affiliation:
            name:Liaqut University of Medical and Health Sciences
            address:
               name:Liaqut University of Medical and Health Sciences, Jamshoro, Pakistan
               type:PostalAddress
            type:Organization
      name:Mohammad Khan Jamali
      affiliation:
            name:Sindh University
            address:
               name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
               type:PostalAddress
            type:Organization
      name:Mohammad Bilal Arain
      affiliation:
            name:Sindh University
            address:
               name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
               type:PostalAddress
            type:Organization
      name:Nussarat Jalbani
      affiliation:
            name:Sindh University
            address:
               name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
               type:PostalAddress
            type:Organization
      name:Ghulam Abbas Kandhro
      affiliation:
            name:Sindh University
            address:
               name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
               type:PostalAddress
            type:Organization
PostalAddress:
      name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
      name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
      name:Liaqut University of Medical and Health Sciences, Jamshoro, Pakistan
      name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
      name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
      name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
      name:National Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro, Pakistan
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(157)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.67s.

LINK . SPRINGER . COM {}