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Title:
Screening for Prostate Cancer—Beyond Total PSA, Utilization of Novel Biomarkers | Current Urology Reports
Description:
Urology has been beset by several major trends that have shifted the entire paradigm for prostate cancer screening. These stem from a backlash against overdiagnosis and overtreatment due to prostate-specific antigen (PSA)-based screening efforts and have led national societies to modify their guidelines. More importantly, the public outcry has shifted the focus of early detection from an effort to diagnose any and all prostate cancers to an effort to diagnose clinically significant prostate cancers at an early stage. This review provides an update on contemporary biomarkers for prostate cancer that may be used to supplement PSA-based screening approaches.
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Keywords {🔍}
cancer, prostate, pubmed, article, google, scholar, cas, pca, screening, psa, antigen, urol, central, biomarkers, detection, urine, study, biopsy, prostatespecific, urology, men, eur, european, early, rna, content, total, wei, clin, specific, privacy, cookies, analysis, serum, diagnosis, med, years, clinical, free, propsa, van, molecular, assay, tmprsserg, data, information, publish, research, search, morgan,
Topics {✒️}
multi-institutional high-throughput analysis month download article/chapter ganesh palapattu & john wei benign prostate-specific antigen de bekker-grob ew prostate-specific antigen screening highest-ranked overexpressed gene total prostate-specific antigen biopsy-specific nomogram based biomarkers prostate cancer tmprss2-erg gene fusions population-based cohort related subjects full article pdf led national societies prognostic urinary biomarkers cancer-specific markers molecular urine test prostate-specific antigen prostate specific antigen privacy choices/manage cookies prostate-specific gene john wei declares animal subjects performed prostate cancer access [-2]proprostate-specific antigen prostate cancer screening prostate cancer screening total psa range based screening efforts digital rectal examination specific serum marker prostate cancer death early prostate cancer detecting prostate cancer community-based sample clinical risk factors natl cancer inst european randomized study randomized european study pca3 urine assay prostate cancer mortality prostate-cancer mortality prostate cancer detection rna biomarkers situ hybridization assay dd3pca3 rna analysis european randomised study multicentric european study elevated serum psa
Questions {❓}
- Can urinary PCA3 supplement PSA in the early detection of prostate cancer?
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description:Urology has been beset by several major trends that have shifted the entire paradigm for prostate cancer screening. These stem from a backlash against overdiagnosis and overtreatment due to prostate-specific antigen (PSA)-based screening efforts and have led national societies to modify their guidelines. More importantly, the public outcry has shifted the focus of early detection from an effort to diagnose any and all prostate cancers to an effort to diagnose clinically significant prostate cancers at an early stage. This review provides an update on contemporary biomarkers for prostate cancer that may be used to supplement PSA-based screening approaches.
datePublished:2015-07-14T00:00:00Z
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