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Title:
The Gut Microbiome and Obesity | Current Oncology Reports
Description:
The gut microbiome consists of trillions of bacteria which play an important role in human metabolism. Animal and human studies have implicated distortion of the normal microbial balance in obesity and metabolic syndrome. Bacteria causing weight gain are thought to induce the expression of genes related to lipid and carbohydrate metabolism thereby leading to greater energy harvest from the diet. There is a large body of evidence demonstrating that alteration in the proportion of Bacteroidetes and Firmicutes leads to the development of obesity, but this has been recently challenged. It is likely that the influence of gut microbiome on obesity is much more complex than simply an imbalance in the proportion of these phyla of bacteria. Modulation of the gut microbiome through diet, pre- and probiotics, antibiotics, surgery, and fecal transplantation has the potential to majorly impact the obesity epidemic.
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Keywords {🔍}
article, pubmed, google, scholar, gut, cas, obesity, microbiota, microbiome, human, central, weight, mullin, metabolic, nutr, microbial, diet, disease, nature, role, metabolism, fecal, dietary, clin, proc, natl, acad, sci, health, overweight, loss, animal, intestinal, early, privacy, cookies, content, bacteria, studies, energy, modulation, transplantation, access, adiposity, turnbaugh, gordon, composition, effect, data, information,
Topics {✒️}
month download article/chapter normal microbial balance low-grade inflammation markers formula-fed human infants probiotic science—report immunoglobulin-coating fecal bacteria gut balance revolution full article pdf turnbaugh pj microbial ecology privacy choices/manage cookies article john infect dev ctries early gut microbiome gut microbiota richness distal gut microbiome firmicutes leads human gut microbiota early life alter gut microbiome consists core gut microbiome human colonic microbiota nat rev immunol curr pharm des murine colonic microbiome gut microbiota composition disorders including obesity european economic area regulates fat storage bacterial growth rates prospectively studied cohort monitoring bacterial community prospective randomized trial microbial consortia impaired glycemic control fao technical meeting middle-aged men expert meeting—london antimicrobial growth promoters critical developmental window low dose penicillin germ free showing recurrent clostridium difficile long term risks johns hopkins hospital human gut microbiome animal subjects performed impacting gut microbiome appl environ microbiol integrative weight management
Questions {❓}
- Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota?
- Is meconium from healthy newborns actually sterile?
- The impact of early life gut colonization on metabolic and obesogenic outcomes: what have animal models shown us?
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headline:The Gut Microbiome and Obesity
description:The gut microbiome consists of trillions of bacteria which play an important role in human metabolism. Animal and human studies have implicated distortion of the normal microbial balance in obesity and metabolic syndrome. Bacteria causing weight gain are thought to induce the expression of genes related to lipid and carbohydrate metabolism thereby leading to greater energy harvest from the diet. There is a large body of evidence demonstrating that alteration in the proportion of Bacteroidetes and Firmicutes leads to the development of obesity, but this has been recently challenged. It is likely that the influence of gut microbiome on obesity is much more complex than simply an imbalance in the proportion of these phyla of bacteria. Modulation of the gut microbiome through diet, pre- and probiotics, antibiotics, surgery, and fecal transplantation has the potential to majorly impact the obesity epidemic.
datePublished:2016-06-02T00:00:00Z
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Obesity
Microbiota
Diet
Prebiotic
Probiotic
Microbial balance
Bacteroidetes
Firmicutes
Oncology
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Microbiota
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Bacteroidetes
Firmicutes
Oncology
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