We are analyzing https://link.springer.com/article/10.1007/s11515-011-1070-5.

Title:
The mechanism of protein kinase C regulation | Frontiers in Biology
Description:
Protein kinase C (PKC) is a family of serine/threonine protein kinases that plays a central role in transducing extracellular signals into a variety of intracellular responses ranging from cell proliferation to apoptosis. Nine PKC genes have been identified in the human genome, which encode 10 proteins. Each member of this protein kinase family displays distinct biochemical characteristics and is enriched in different cellular and subcellular locations. Activation of PKC has been implicated in the regulation of cell growth and differentiation. This review summarizes works of the past years in the field of PKC biochemistry that covers regulation and activation mechanism of different PKC isoforms.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Health & Fitness
Sports

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We don't see any clear sign of profit-making.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Link.springer.com could have a money-making trick up its sleeve, but it's undetectable for now.

Keywords {🔍}

kinase, protein, pubmed, google, scholar, article, cas, biol, chem, domain, pkc, phosphorylation, activation, structure, cell, regulation, newton, biochem, tyrosine, delta, sci, kazi, proc, natl, acad, parker, function, biochemistry, pdk, nishizuka, atypical, privacy, cookies, content, mechanism, julhash, characterization, signalling, febs, lett, kikkawa, phorbol, curr, calpha, complex, crystal, mol, site, data, publish,

Topics {✒️}

12-o-tetradecanoylphorbol-13-acetate-induced dephosphorylation month download article/chapter c-abl tyrosine kinase tumor-promoting phorbol esters ceramide-activated protein phosphatases lck-mediated tyrosine phosphorylation cys2 activator-binding domain protein kinase c-theta signalling pathways regulating phorbol ester-induced translocation protein-lipid micelle interactions protein kinase c-alpha cellular signal transduction serine/threonine protein kinases protein kinase c-delta c2 membrane-binding domain 3-phosphoinositide-dependent protein kinase-1 intracellular responses ranging full article pdf oxidative stress-mediated activation phospholipids-dependent protein kinase calcium-binding sites src kinase pathway privacy choices/manage cookies membrane binding mode functionally distinct phosphorylations high affinity receptor atypical pkc complex atypical protein kinase human protein kinase beta ii complexed phosphotyrosine binding domain related subjects membrane binding residues membrane binding model tyrosine phosphorylation sites protein kinase calpha activation loop phosphorylations conventional protein kinase eukaryotic protein kinases protein phosphatase 2ac tyrosine phosphorylation site phosphoinositide-dependent kinase 1 nat rev cancer h2o2-treated cells nih 3t3 cells signal transduction article frontiers extended protein kinase purified protein kinase

Questions {❓}

Targeting the protein kinase C family: are we there yet?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:The mechanism of protein kinase C regulation
         description:Protein kinase C (PKC) is a family of serine/threonine protein kinases that plays a central role in transducing extracellular signals into a variety of intracellular responses ranging from cell proliferation to apoptosis. Nine PKC genes have been identified in the human genome, which encode 10 proteins. Each member of this protein kinase family displays distinct biochemical characteristics and is enriched in different cellular and subcellular locations. Activation of PKC has been implicated in the regulation of cell growth and differentiation. This review summarizes works of the past years in the field of PKC biochemistry that covers regulation and activation mechanism of different PKC isoforms.
         datePublished:2011-07-29T00:00:00Z
         dateModified:2011-07-29T00:00:00Z
         pageStart:328
         pageEnd:336
         sameAs:https://doi.org/10.1007/s11515-011-1070-5
         keywords:
            PKC
            biochemistry
            PKC kinase
            PKC phosphatases
            PKC structure
            Proteomics
            Neurobiology
            Genetics and Population Dynamics
            Developmental Biology
            Biochemistry
            general
            Cell Biology
         image:
         isPartOf:
            name:Frontiers in Biology
            issn:
               1673-3622
               1674-7984
            volumeNumber:6
            type:
               Periodical
               PublicationVolume
         publisher:
            name:SP Higher Education Press
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Julhash U. Kazi
               affiliation:
                     name:KN Biomedical Research Institute
                     address:
                        name:Laboratory of Computational Biochemistry, KN Biomedical Research Institute, Barisal, Bangladesh
                        type:PostalAddress
                     type:Organization
                     name:Opsonin Pharma Ltd
                     address:
                        name:Quality Control Section, Opsonin Pharma Ltd, Barisal, Bangladesh
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:The mechanism of protein kinase C regulation
      description:Protein kinase C (PKC) is a family of serine/threonine protein kinases that plays a central role in transducing extracellular signals into a variety of intracellular responses ranging from cell proliferation to apoptosis. Nine PKC genes have been identified in the human genome, which encode 10 proteins. Each member of this protein kinase family displays distinct biochemical characteristics and is enriched in different cellular and subcellular locations. Activation of PKC has been implicated in the regulation of cell growth and differentiation. This review summarizes works of the past years in the field of PKC biochemistry that covers regulation and activation mechanism of different PKC isoforms.
      datePublished:2011-07-29T00:00:00Z
      dateModified:2011-07-29T00:00:00Z
      pageStart:328
      pageEnd:336
      sameAs:https://doi.org/10.1007/s11515-011-1070-5
      keywords:
         PKC
         biochemistry
         PKC kinase
         PKC phosphatases
         PKC structure
         Proteomics
         Neurobiology
         Genetics and Population Dynamics
         Developmental Biology
         Biochemistry
         general
         Cell Biology
      image:
      isPartOf:
         name:Frontiers in Biology
         issn:
            1673-3622
            1674-7984
         volumeNumber:6
         type:
            Periodical
            PublicationVolume
      publisher:
         name:SP Higher Education Press
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Julhash U. Kazi
            affiliation:
                  name:KN Biomedical Research Institute
                  address:
                     name:Laboratory of Computational Biochemistry, KN Biomedical Research Institute, Barisal, Bangladesh
                     type:PostalAddress
                  type:Organization
                  name:Opsonin Pharma Ltd
                  address:
                     name:Quality Control Section, Opsonin Pharma Ltd, Barisal, Bangladesh
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Frontiers in Biology
      issn:
         1673-3622
         1674-7984
      volumeNumber:6
Organization:
      name:SP Higher Education Press
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:KN Biomedical Research Institute
      address:
         name:Laboratory of Computational Biochemistry, KN Biomedical Research Institute, Barisal, Bangladesh
         type:PostalAddress
      name:Opsonin Pharma Ltd
      address:
         name:Quality Control Section, Opsonin Pharma Ltd, Barisal, Bangladesh
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Julhash U. Kazi
      affiliation:
            name:KN Biomedical Research Institute
            address:
               name:Laboratory of Computational Biochemistry, KN Biomedical Research Institute, Barisal, Bangladesh
               type:PostalAddress
            type:Organization
            name:Opsonin Pharma Ltd
            address:
               name:Quality Control Section, Opsonin Pharma Ltd, Barisal, Bangladesh
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Laboratory of Computational Biochemistry, KN Biomedical Research Institute, Barisal, Bangladesh
      name:Quality Control Section, Opsonin Pharma Ltd, Barisal, Bangladesh
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(241)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

4.4s.

LINK . SPRINGER . COM {}