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Title:
The role of virus-derived small interfering RNAs in RNA silencing in plants | Science China Life Sciences
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Antiviral defense is one of the important roles of RNA silencing in plants. Virus-derived small interfering RNAs (vsiRNAs) are found in the infected host cells, indicating that the host RNA silencing machinery can target viral RNAs for destruction. With the development of high-throughput sequencing of vsiRNAs, recent genetic studies have shed light on the origin and composition of vsiRNAs and their potential functions in the regulation of gene expression. Here, we briefly describe the origin and biogenesis of vsiRNAs, and review the recent discoveries regarding vsiRNA-mediated RNA silencing of viral genomes and host transcripts. This will better our understanding of virus pathogenicity and RNA silencing-related host-pathogen interactions in plants.
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mainEntity:
headline:The role of virus-derived small interfering RNAs in RNA silencing in plants
description:Antiviral defense is one of the important roles of RNA silencing in plants. Virus-derived small interfering RNAs (vsiRNAs) are found in the infected host cells, indicating that the host RNA silencing machinery can target viral RNAs for destruction. With the development of high-throughput sequencing of vsiRNAs, recent genetic studies have shed light on the origin and composition of vsiRNAs and their potential functions in the regulation of gene expression. Here, we briefly describe the origin and biogenesis of vsiRNAs, and review the recent discoveries regarding vsiRNA-mediated RNA silencing of viral genomes and host transcripts. This will better our understanding of virus pathogenicity and RNA silencing-related host-pathogen interactions in plants.
datePublished:2012-03-15T00:00:00Z
dateModified:2012-03-15T00:00:00Z
pageStart:119
pageEnd:125
license:https://creativecommons.org/licenses/by/2.0
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keywords:
vsiRNA
RNA silencing
virus pathogenicity
gene regulation
Life Sciences
general
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1869-1889
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author:
name:Hui Zhu
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name:Chinese Academy of Sciences
address:
name:State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
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name:HuiShan Guo
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ScholarlyArticle:
headline:The role of virus-derived small interfering RNAs in RNA silencing in plants
description:Antiviral defense is one of the important roles of RNA silencing in plants. Virus-derived small interfering RNAs (vsiRNAs) are found in the infected host cells, indicating that the host RNA silencing machinery can target viral RNAs for destruction. With the development of high-throughput sequencing of vsiRNAs, recent genetic studies have shed light on the origin and composition of vsiRNAs and their potential functions in the regulation of gene expression. Here, we briefly describe the origin and biogenesis of vsiRNAs, and review the recent discoveries regarding vsiRNA-mediated RNA silencing of viral genomes and host transcripts. This will better our understanding of virus pathogenicity and RNA silencing-related host-pathogen interactions in plants.
datePublished:2012-03-15T00:00:00Z
dateModified:2012-03-15T00:00:00Z
pageStart:119
pageEnd:125
license:https://creativecommons.org/licenses/by/2.0
sameAs:https://doi.org/10.1007/s11427-012-4281-3
keywords:
vsiRNA
RNA silencing
virus pathogenicity
gene regulation
Life Sciences
general
image:
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1869-1889
1674-7305
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name:State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
name:State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
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