We are analyzing https://link.springer.com/article/10.1007/s11427-012-4267-1.

Title:
Functions of chromatin remodeling factors in heterochromatin formation and maintenance | Science China Life Sciences
Description:
Heterochromatin is characteristically more compact than euchromatin in the eukaryotic genome. The establishment of heterochromatin is mediated by special histone modifications, recruitment and propagation of heterochromatin specific proteins, as well as formation of special primary and high order structures of chromatin. Chromatin remodeling factors are ATPases that can alter the conformation and/or positioning of nucleosomes along DNA in an ATP-dependent manner. There is increasing evidence implicating chromatin remodeling activities in heterochromatin in various organisms ranging from yeasts to humans. Chromatin remodeling factors play roles in the establishment, maintenance and epigenetic inheritance of heterochromatin, but the underlying molecular mechanisms have just begun to be investigated.
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Keywords {🔍}

pubmed, article, google, scholar, cas, chromatin, heterochromatin, central, cell, remodeling, biol, formation, mol, silencing, function, replication, structure, gene, complex, protein, sci, access, atrx, usa, university, factors, open, saccharomyces, cerevisiae, privacy, cookies, science, maintenance, proteins, epigenetic, inheritance, biochem, drosophila, iswi, rochester, content, analysis, information, publish, search, china, download, xin, histone, structures,

Topics {✒️}

acf1-iswi chromatin-remodeling complex chromatin-remodeling factor brg1 snf2-homolog fun30 acts replication requires swi/snf article download pdf long-range nucleosome ordering high-resolution structural analysis mi-2/nurd complex associates x-linked mental retardation china life sci heterochromatin-induced gene silencing atrx-add domain binds chicken beta-globin insulator swi/snf protein atrx chromatin remodeling factors transcriptionally silent chromatin target chromatin remodelling chromatin-remodeling complex fun30 chromatin remodeler chromatin remodeling complexes atp-dependent manner chromatin remodeling machinery open access heterochromatic transcriptional silencing altered chromatin structure specialized chromatin structure heat shock locus privacy choices/manage cookies nucleosome-assembly protein pml nuclear bodies chromatin structures flanking high order structures higher order domains nucleosome-excluding structures neves-costa si lent chromatin chromatin remodeler smarcad1 nucleosome core particle transcription repressor daxx putative transcriptional regulator replication foci related subjects eukaryotic gene regulation pericentric beta-heterochromatin special histone modifications article bi conserved structural motifs heterochromatin specific proteins nucleic acids res combined methylation state

Questions {❓}

Chromatin remodeling by WSTF-ISWI at the replication site: opening a window of opportunity for epigenetic inheritance?

Schema {🗺️}

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         headline:Functions of chromatin remodeling factors in heterochromatin formation and maintenance
         description:Heterochromatin is characteristically more compact than euchromatin in the eukaryotic genome. The establishment of heterochromatin is mediated by special histone modifications, recruitment and propagation of heterochromatin specific proteins, as well as formation of special primary and high order structures of chromatin. Chromatin remodeling factors are ATPases that can alter the conformation and/or positioning of nucleosomes along DNA in an ATP-dependent manner. There is increasing evidence implicating chromatin remodeling activities in heterochromatin in various organisms ranging from yeasts to humans. Chromatin remodeling factors play roles in the establishment, maintenance and epigenetic inheritance of heterochromatin, but the underlying molecular mechanisms have just begun to be investigated.
         datePublished:2012-02-08T00:00:00Z
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            chromatin remodeling
            gene silencing
            heterochromatin
            inheritance
            nucleosome
            replication
            Life Sciences
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      headline:Functions of chromatin remodeling factors in heterochromatin formation and maintenance
      description:Heterochromatin is characteristically more compact than euchromatin in the eukaryotic genome. The establishment of heterochromatin is mediated by special histone modifications, recruitment and propagation of heterochromatin specific proteins, as well as formation of special primary and high order structures of chromatin. Chromatin remodeling factors are ATPases that can alter the conformation and/or positioning of nucleosomes along DNA in an ATP-dependent manner. There is increasing evidence implicating chromatin remodeling activities in heterochromatin in various organisms ranging from yeasts to humans. Chromatin remodeling factors play roles in the establishment, maintenance and epigenetic inheritance of heterochromatin, but the underlying molecular mechanisms have just begun to be investigated.
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         gene silencing
         heterochromatin
         inheritance
         nucleosome
         replication
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         general
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