We are analyzing https://link.springer.com/article/10.1007/s11427-011-4257-8.

Title:
Cardinal roles of miRNA in cardiac development and disease | Science China Life Sciences
Description:
MicroRNAs (miRNAs) are small noncoding RNAs that are emerging as pivotal modulators in virtually all aspects of cardiac biology, from cardiac development to cardiomyocyte survival and hypertrophy. The miRNA profiling, following gain- and loss-of-function studies using in vitro and in vivo models, has identified wide-ranging functions for miRNAs in the heart, providing new perspectives on their contributions to cardiac pathogenesis, and revealing potential therapeutic targets and diagnostic biomarkers. This review summarizes current progress in regulation of miRNAs in heart development and disease.
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Keywords {🔍}

pubmed, article, google, scholar, cas, cardiac, central, microrna, heart, cell, micrornas, hypertrophy, development, res, expression, myocardial, access, disease, open, sci, circulating, circulation, circ, biol, mirnas, regulates, zhang, wang, infarction, mirna, potential, regulation, lin, gene, mol, med, privacy, cookies, china, cardiomyocyte, cardiovascular, human, nature, genes, ventricular, micrornaa, nat, clin, targeting, yang,

Topics {✒️}

china life sci single-channel properties support article download pdf small noncoding rnas identified wide-ranging functions pressure-overloaded adult hearts mir-23a functions downstream muscle-specific micrornas mir-1 gata-4-mediated mir-144/451 cluster cardiac ischemia/reperfusion injury stress-dependent cardiac growth xiyong yu cardinal roles article feng muscle-specific microrna circulating cell-free microrna-1 medical sciences ventricular arrhythmias induced dynamin-related protein-1 privacy choices/manage cookies stem cell engraftment fetal gene reprogramming open access modulates electrical repolarization microrna-133a protects exosome-mediated transfer related subjects calcium-calcineurin signaling microrna-133a levels mir-1/mir-133 contributes target mrna degradation tissue-specific micrornas search search altered microrna expression recapitulates hypoxia preconditioning cyclic ischemic preconditioning human cytomegalovirus infection microrna expression signature ischemic ventricular arrhythmias microrna-199b targets extracellular circulating microrna circulating microrna-208b european economic area transcoronary concentration gradients nuclear kinase dyrk1a antioxid redox signal episodic electrical phenotypes evoke cardiac hypertrophy regulate cardiac hypertrophy conditions privacy policy

Questions {❓}

Cardiac remodelling and myocardial recovery: lost in translation?
MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy?

Schema {🗺️}

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         description:MicroRNAs (miRNAs) are small noncoding RNAs that are emerging as pivotal modulators in virtually all aspects of cardiac biology, from cardiac development to cardiomyocyte survival and hypertrophy. The miRNA profiling, following gain- and loss-of-function studies using in vitro and in vivo models, has identified wide-ranging functions for miRNAs in the heart, providing new perspectives on their contributions to cardiac pathogenesis, and revealing potential therapeutic targets and diagnostic biomarkers. This review summarizes current progress in regulation of miRNAs in heart development and disease.
         datePublished:2012-01-07T00:00:00Z
         dateModified:2012-01-07T00:00:00Z
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      headline:Cardinal roles of miRNA in cardiac development and disease
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               name:Medical Research Center of Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
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      name:Southern Medical University Pharmaceutical School, Guangzhou, China
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