We are analyzing https://link.springer.com/article/10.1007/s11427-010-4073-6.

Title:
Marek’s disease virus-encoded microRNAs: genomics, expression and function | Science China Life Sciences
Description:
MicroRNAs (miRNAs) are the recently discovered small non-coding RNA molecules that have post-transcriptional regulatory functions in many important biological processes. A large number of miRNAs have been found to be encoded by viral genomes, especially in herpesviruses. Previous research regarding miRNAs encoded by herpesviruses, including Marek’s disease virus (MDV), has demonstrated their involvement in lytic replication, latent infection, T-lymphocyte transformation and tumorigenesis. MDV is an oncogenic alphaherpesvirus, with the ability to induce tumors in natural hosts; however, formation of these tumors can be prevented by immunization with attenuated or nonpathogenic forms of the virus. Marek’s disease is considered to be a good biomedical model for investigating the biology, genetics, and immunology of tumorigenesis. In this paper, we review the discovery and identification of MDV-encoded miRNAs, along with their genomics, expression profiles, and currently known functions. We also discuss the prospects and techniques possibly applicable to the further investigation of the biological roles of MDV-encoded miRNAs.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Education
Health & Fitness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,642,828 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We can't see how the site brings in money.

Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Link.springer.com could be getting rich in stealth mode, or the way it's monetizing isn't detectable.

Keywords {🔍}

pubmed, article, google, scholar, cas, mareks, disease, virus, central, micrornas, virol, jvi, herpesvirus, mirnas, mdv, rnas, gene, cell, expression, access, sci, privacy, cookies, content, research, china, virusencoded, noncoding, encoded, open, lee, anderson, yao, zhao, function, information, publish, search, genomics, fan, herpesviruses, immunology, lin, usa, morgan, data, log, journal, life, sciences,

Topics {✒️}

month download article/chapter rev-ltr integration retained china life sci mir-221 controls cdkn1c//p57 post-transcriptional regulatory functions heterochronic gene lin-14 dc%2bd1cxnt1ensa%3d%3d full article pdf recently discovered small bacterial artificial chromosomes 1007/s11427-010-4113-2 rights privacy choices/manage cookies disease virus-encoded micrornas related subjects human hepatocellular carcinoma disease virus encodes bacterial artificial chromosome gene transcription long icp4 homolog gene coding rnas mirnas encoded micrornas show t-lymphocyte transformation coding rna molecules fos/jun oncogenes chin sci bull article luo post-transcriptional regulation elsevier academic press long repeat regions gaiping zhang nat rev genet nat rev microbiol virus-induced tumours european economic area techniques possibly applicable nucl acids res dtsch tierarztl wochenschr hooft van iddekinge dyak2cxpslgqta%3d%3d dyak2cxislyisa%3d%3d dyal38xpvvklsw%3d%3d dyak3mxls1cmtq%3d%3d dyak2sxls1cltg%3d%3d dc%2bd3sxhtvsrur%2fo dc%2bd1cxhsvymsl%2fo dc%2bd2cxhtvaqur%2fp dc%2bd2cxhtvals7o%3d dc%2bd1cxntvcjtr4%3d dc%2bd1mxis1aiu7o%3d dc%2bd2cxntvers7o%3d

Questions {❓}

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Marek’s disease virus-encoded microRNAs: genomics, expression and function
         description:MicroRNAs (miRNAs) are the recently discovered small non-coding RNA molecules that have post-transcriptional regulatory functions in many important biological processes. A large number of miRNAs have been found to be encoded by viral genomes, especially in herpesviruses. Previous research regarding miRNAs encoded by herpesviruses, including Marek’s disease virus (MDV), has demonstrated their involvement in lytic replication, latent infection, T-lymphocyte transformation and tumorigenesis. MDV is an oncogenic alphaherpesvirus, with the ability to induce tumors in natural hosts; however, formation of these tumors can be prevented by immunization with attenuated or nonpathogenic forms of the virus. Marek’s disease is considered to be a good biomedical model for investigating the biology, genetics, and immunology of tumorigenesis. In this paper, we review the discovery and identification of MDV-encoded miRNAs, along with their genomics, expression profiles, and currently known functions. We also discuss the prospects and techniques possibly applicable to the further investigation of the biological roles of MDV-encoded miRNAs.
         datePublished:2010-10-17T00:00:00Z
         dateModified:2010-10-17T00:00:00Z
         pageStart:1174
         pageEnd:1180
         sameAs:https://doi.org/10.1007/s11427-010-4073-6
         keywords:
            MDV
            miRNA
            herpesvirus
            cancer
            tumorigenesis
            Life Sciences
            general
         image:
         isPartOf:
            name:Science China Life Sciences
            issn:
               1869-1889
               1674-7305
            volumeNumber:53
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Science China Press
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Jun Luo
               affiliation:
                     name:Henan Academy of Agricultural Sciences
                     address:
                        name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Man Teng
               affiliation:
                     name:Henan Academy of Agricultural Sciences
                     address:
                        name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:JianMing Fan
               affiliation:
                     name:Henan Academy of Agricultural Sciences
                     address:
                        name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
                     name:Zhengzhou University
                     address:
                        name:Laboratory of Toxicology, College of Public Health, Zhengzhou University, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:FangYu Wang
               affiliation:
                     name:Henan Academy of Agricultural Sciences
                     address:
                        name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ling Zhou
               affiliation:
                     name:Henan Academy of Agricultural Sciences
                     address:
                        name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:RuiGuang Deng
               affiliation:
                     name:Henan Academy of Agricultural Sciences
                     address:
                        name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
               type:Person
               name:GaiPing Zhang
               affiliation:
                     name:Henan Academy of Agricultural Sciences
                     address:
                        name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Marek’s disease virus-encoded microRNAs: genomics, expression and function
      description:MicroRNAs (miRNAs) are the recently discovered small non-coding RNA molecules that have post-transcriptional regulatory functions in many important biological processes. A large number of miRNAs have been found to be encoded by viral genomes, especially in herpesviruses. Previous research regarding miRNAs encoded by herpesviruses, including Marek’s disease virus (MDV), has demonstrated their involvement in lytic replication, latent infection, T-lymphocyte transformation and tumorigenesis. MDV is an oncogenic alphaherpesvirus, with the ability to induce tumors in natural hosts; however, formation of these tumors can be prevented by immunization with attenuated or nonpathogenic forms of the virus. Marek’s disease is considered to be a good biomedical model for investigating the biology, genetics, and immunology of tumorigenesis. In this paper, we review the discovery and identification of MDV-encoded miRNAs, along with their genomics, expression profiles, and currently known functions. We also discuss the prospects and techniques possibly applicable to the further investigation of the biological roles of MDV-encoded miRNAs.
      datePublished:2010-10-17T00:00:00Z
      dateModified:2010-10-17T00:00:00Z
      pageStart:1174
      pageEnd:1180
      sameAs:https://doi.org/10.1007/s11427-010-4073-6
      keywords:
         MDV
         miRNA
         herpesvirus
         cancer
         tumorigenesis
         Life Sciences
         general
      image:
      isPartOf:
         name:Science China Life Sciences
         issn:
            1869-1889
            1674-7305
         volumeNumber:53
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Science China Press
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Jun Luo
            affiliation:
                  name:Henan Academy of Agricultural Sciences
                  address:
                     name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Man Teng
            affiliation:
                  name:Henan Academy of Agricultural Sciences
                  address:
                     name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:JianMing Fan
            affiliation:
                  name:Henan Academy of Agricultural Sciences
                  address:
                     name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
                  name:Zhengzhou University
                  address:
                     name:Laboratory of Toxicology, College of Public Health, Zhengzhou University, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:FangYu Wang
            affiliation:
                  name:Henan Academy of Agricultural Sciences
                  address:
                     name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ling Zhou
            affiliation:
                  name:Henan Academy of Agricultural Sciences
                  address:
                     name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:RuiGuang Deng
            affiliation:
                  name:Henan Academy of Agricultural Sciences
                  address:
                     name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
            type:Person
            name:GaiPing Zhang
            affiliation:
                  name:Henan Academy of Agricultural Sciences
                  address:
                     name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Science China Life Sciences
      issn:
         1869-1889
         1674-7305
      volumeNumber:53
Organization:
      name:Science China Press
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Henan Academy of Agricultural Sciences
      address:
         name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
         type:PostalAddress
      name:Henan Academy of Agricultural Sciences
      address:
         name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
         type:PostalAddress
      name:Henan Academy of Agricultural Sciences
      address:
         name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
         type:PostalAddress
      name:Zhengzhou University
      address:
         name:Laboratory of Toxicology, College of Public Health, Zhengzhou University, Zhengzhou, China
         type:PostalAddress
      name:Henan Academy of Agricultural Sciences
      address:
         name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
         type:PostalAddress
      name:Henan Academy of Agricultural Sciences
      address:
         name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
         type:PostalAddress
      name:Henan Academy of Agricultural Sciences
      address:
         name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
         type:PostalAddress
      name:Henan Academy of Agricultural Sciences
      address:
         name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Jun Luo
      affiliation:
            name:Henan Academy of Agricultural Sciences
            address:
               name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
               type:PostalAddress
            type:Organization
      name:Man Teng
      affiliation:
            name:Henan Academy of Agricultural Sciences
            address:
               name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
               type:PostalAddress
            type:Organization
      name:JianMing Fan
      affiliation:
            name:Henan Academy of Agricultural Sciences
            address:
               name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
               type:PostalAddress
            type:Organization
            name:Zhengzhou University
            address:
               name:Laboratory of Toxicology, College of Public Health, Zhengzhou University, Zhengzhou, China
               type:PostalAddress
            type:Organization
      name:FangYu Wang
      affiliation:
            name:Henan Academy of Agricultural Sciences
            address:
               name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
               type:PostalAddress
            type:Organization
      name:Ling Zhou
      affiliation:
            name:Henan Academy of Agricultural Sciences
            address:
               name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
               type:PostalAddress
            type:Organization
      name:RuiGuang Deng
      affiliation:
            name:Henan Academy of Agricultural Sciences
            address:
               name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
               type:PostalAddress
            type:Organization
      name:GaiPing Zhang
      affiliation:
            name:Henan Academy of Agricultural Sciences
            address:
               name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
      name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
      name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
      name:Laboratory of Toxicology, College of Public Health, Zhengzhou University, Zhengzhou, China
      name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
      name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
      name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
      name:Key Laboratory of Animal Immunology of Ministry of Agriculture, Henan Provincial Key Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, China
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(155)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.95s.

LINK . SPRINGER . COM {}