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Title:
Whole genome characterisation of quail deltacoronavirus detected in Poland | Virus Genes
Description:
Quail deltacoronavirus (QdCoV) described for the first time in the United Arab Emirates in 2018 belongs to the same deltacoronavirus species as viruses discovered in swine and tree sparrows. The full-length genome of QdCoV detected in quails with enteritis in Poland has similar organization as Middle Eastern viruses although there is no NSP7c gene. The overall degree of nucleotide sequence identity was 92.4–92.6% between Polish PL/G032/2015 and Middle Eastern UAE-HKU30 QdCoV isolates. The sequences of the individual genes show similar nucleotide identities in the range of 91.4–94.7% with the exception of the S gene with lower identity of 85.6–85.7%. The most variable part of the S gene is its fragment encoding the N-terminal domain of the S protein which is responsible for receptor binding. The amino acid homology in this region between PL/G032/2015 and UAE-HKU30 QdCoVs was 74.5–74.7%. In contrast, the C-terminal domain of the S protein which is responsible for membrane fusion had an amino acid homology of 96.9%. In the phylogenetic tree, PL/G032/2015 branched separately but clustered with the UAE-HKU30 QdCoV isolates. These data suggest that PL/G032/2015 could be a new genetic/serologic variant of QdCoV.
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Keywords {🔍}
article, gene, amino, pubmed, genome, qdcov, google, scholar, quail, avian, virus, qdcovplg, deltacoronavirus, sequence, acid, strain, cas, coronavirus, nucleotide, polish, uaehku, middle, identity, position, analysis, poland, acids, quails, eastern, protein, genes, detected, sequences, virol, site, viruses, responsible, homology, qdcovs, phylogenetic, coronaviruses, hku, study, birds, complete, table, strains, detection, dis, privacy,
Topics {✒️}
structure 5′utr-orf1a/1b-s-e-m-ns6-n-ns7a-ns7b-3′utr qdcov/pl/g032/2015 strain formed qdcov/pl/g032/2015 strain grouped qdcov/pl/g032/2015 strain determined real-time pcr assay qdcov/pl/g032/2015 shared 95 pl/g032/2015 branched separately article download pdf qdcov/pl/g032/2015 strain full-length genome consists qdcov uae-hku30 strains multiplex rt-pcr test named qdcov/pl/g032/2015 uae-hku30 qdcov isolates article domańska-blicharz full-length genome sequence katarzyna domańska-blicharz rt-pcr results revealed short-lived diarrhea appeared qdcovs uae-hku30 isolates polish qdcov/pl/g032/2015 qdcov uae-hku30 belongs positive-sense ssrna viruses sajewicz-krukowska uae-hku30 strains n-terminal domain uea-hku30 dcovs full-length genome qdcov/pl/g032/2015 uae-hku30 qdcovs polish pl/g032/2015 privacy choices/manage cookies middle eastern isolates polish qdcov strain full genomes revealed middle eastern viruses middle eastern qdcovs infectious bronchitis virus national veterinary institute nonstructural genes encoding c-terminal domain complete genome level watery diarrhea started respective regions/genes complete genome sequences full access compared qdcov strains quail dcov originated united arab emirates genetic/serologic variant
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headline:Whole genome characterisation of quail deltacoronavirus detected in Poland
description:Quail deltacoronavirus (QdCoV) described for the first time in the United Arab Emirates in 2018 belongs to the same deltacoronavirus species as viruses discovered in swine and tree sparrows. The full-length genome of QdCoV detected in quails with enteritis in Poland has similar organization as Middle Eastern viruses although there is no NSP7c gene. The overall degree of nucleotide sequence identity was 92.4–92.6% between Polish PL/G032/2015 and Middle Eastern UAE-HKU30 QdCoV isolates. The sequences of the individual genes show similar nucleotide identities in the range of 91.4–94.7% with the exception of the S gene with lower identity of 85.6–85.7%. The most variable part of the S gene is its fragment encoding the N-terminal domain of the S protein which is responsible for receptor binding. The amino acid homology in this region between PL/G032/2015 and UAE-HKU30 QdCoVs was 74.5–74.7%. In contrast, the C-terminal domain of the S protein which is responsible for membrane fusion had an amino acid homology of 96.9%. In the phylogenetic tree, PL/G032/2015 branched separately but clustered with the UAE-HKU30 QdCoV isolates. These data suggest that PL/G032/2015 could be a new genetic/serologic variant of QdCoV.
datePublished:2019-02-13T00:00:00Z
dateModified:2019-02-13T00:00:00Z
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Deltacoronavirus
Quail
Genetic characterisation
Poland
Medical Microbiology
Virology
Plant Sciences
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headline:Whole genome characterisation of quail deltacoronavirus detected in Poland
description:Quail deltacoronavirus (QdCoV) described for the first time in the United Arab Emirates in 2018 belongs to the same deltacoronavirus species as viruses discovered in swine and tree sparrows. The full-length genome of QdCoV detected in quails with enteritis in Poland has similar organization as Middle Eastern viruses although there is no NSP7c gene. The overall degree of nucleotide sequence identity was 92.4–92.6% between Polish PL/G032/2015 and Middle Eastern UAE-HKU30 QdCoV isolates. The sequences of the individual genes show similar nucleotide identities in the range of 91.4–94.7% with the exception of the S gene with lower identity of 85.6–85.7%. The most variable part of the S gene is its fragment encoding the N-terminal domain of the S protein which is responsible for receptor binding. The amino acid homology in this region between PL/G032/2015 and UAE-HKU30 QdCoVs was 74.5–74.7%. In contrast, the C-terminal domain of the S protein which is responsible for membrane fusion had an amino acid homology of 96.9%. In the phylogenetic tree, PL/G032/2015 branched separately but clustered with the UAE-HKU30 QdCoV isolates. These data suggest that PL/G032/2015 could be a new genetic/serologic variant of QdCoV.
datePublished:2019-02-13T00:00:00Z
dateModified:2019-02-13T00:00:00Z
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Deltacoronavirus
Quail
Genetic characterisation
Poland
Medical Microbiology
Virology
Plant Sciences
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