We are analyzing https://link.springer.com/article/10.1007/s11103-010-9665-9.

Title:
Histone dynamics and roles of histone acetyltransferases during cold-induced gene regulation in Arabidopsis | Plant Molecular Biology
Description:
In Arabidopsis, CBF transcription factors bind to and activate certain cold-regulated (COR) gene promoters during cold acclimation. Consistent with the prevailing model that histone acetylation and nucleosomal depletion correspond with transcriptionally active genes, we now report that H3 acetylation increases and nucleosome occupancy decreases at COR gene promoters upon cold acclimation. Overexpression of CBF1 resulted in a constitutive increase in H3 acetylation and decrease in nucleosome occupancy, consistent with the constitutive activation of COR gene expression. Overexpression of a truncated form of CBF2 lacking its transcriptional activation domain resulted in a cold-stimulated increase in H3 acetylation, but no change in nucleosomal occupancy or COR gene expression, indicating that histone acetylation is congruent with but not sufficient for cold-activation of COR gene expression. Plants homozygous for T-DNA disruption alleles of GCN5 (encoding a histone acetyltransferase) or ADA2b (a GCN5-interacting protein) show diminished expression of COR genes during cold acclimation. Contrary to expectations, H3 acetylation at COR gene promoters was stimulated upon cold acclimation in ada2b and gcn5 plants as in wild type plants, but the decrease in nucleosome occupancy was diminished. Thus, GCN5 is not the HAT responsible for histone acetylation at COR gene promoters during cold acclimation. Several other HAT mutant plants were also tested; although some do affect COR gene expression, none affected histone acetylation. Therefore, H3 acetylation at the COR gene promoters is not solely dependent on any of the HATs tested.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Science
Telecommunications

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,016 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We can't see how the site brings in money.

Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Link.springer.com might have a hidden revenue stream, but it's not something we can detect.

Keywords {🔍}

article, pubmed, google, scholar, cas, histone, gene, arabidopsis, plant, acetylation, biol, cell, thomashow, cbf, mol, expression, transcriptional, ada, cor, transcription, gcn, triezenberg, complex, genes, regulation, cold, acetyltransferase, gilmour, usa, acclimation, thaliana, chem, berger, saga, research, molecular, nucleosome, plants, role, sci, yeast, acetyltransferases, pavangadkar, promoters, nucleosomal, coactivator, functions, required, factor, allis,

Topics {✒️}

month download article/chapter low-temperature-responsive gene expression tata-binding protein interaction cold-induced gene regulation pkkp/ragrxkfxetrhp signature sequence eukaryotic protein-coding genes light-responsive gene expression aba-regulated gene expression cold-regulated gene expression human spt3-tafii31-gcn5 hat mutant plants t-dna disruption alleles p53 c-terminal domain histone acetyltransferase proteins arabidopsis thaliana cor15a full article pdf arabidopsis cbf family c-repeat/dre transcription factor access cis-acting element privacy choices/manage cookies related subjects plant cold acclimation plant cbp/p300 gcn5-interacting protein arabidopsis thaliana cor histone acetyltransferase activity histone acetyltransferase athac1 histone acetylation dynamics improve stress responses low temperature stress high-salt stress wild type plants multiple hydrophobic motifs regulate gene expression taf1/haf2 interact transcriptional activator involved yeast ho gene cis-acting elements transcriptional coactivator ada2 transcriptional networks involved distinct components involved cor gene expression yeast gcn5 functions de-fg02-91er20021 gene polypeptides cor15am cor gene promoters low temperature regulation histone amino termini matching functional activities

Questions {❓}

Thomashow MF (2001) So what’s new in the field of plant cold acclimation?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Histone dynamics and roles of histone acetyltransferases during cold-induced gene regulation in Arabidopsis
         description:In Arabidopsis, CBF transcription factors bind to and activate certain cold-regulated (COR) gene promoters during cold acclimation. Consistent with the prevailing model that histone acetylation and nucleosomal depletion correspond with transcriptionally active genes, we now report that H3 acetylation increases and nucleosome occupancy decreases at COR gene promoters upon cold acclimation. Overexpression of CBF1 resulted in a constitutive increase in H3 acetylation and decrease in nucleosome occupancy, consistent with the constitutive activation of COR gene expression. Overexpression of a truncated form of CBF2 lacking its transcriptional activation domain resulted in a cold-stimulated increase in H3 acetylation, but no change in nucleosomal occupancy or COR gene expression, indicating that histone acetylation is congruent with but not sufficient for cold-activation of COR gene expression. Plants homozygous for T-DNA disruption alleles of GCN5 (encoding a histone acetyltransferase) or ADA2b (a GCN5-interacting protein) show diminished expression of COR genes during cold acclimation. Contrary to expectations, H3 acetylation at COR gene promoters was stimulated upon cold acclimation in ada2b and gcn5 plants as in wild type plants, but the decrease in nucleosome occupancy was diminished. Thus, GCN5 is not the HAT responsible for histone acetylation at COR gene promoters during cold acclimation. Several other HAT mutant plants were also tested; although some do affect COR gene expression, none affected histone acetylation. Therefore, H3 acetylation at the COR gene promoters is not solely dependent on any of the HATs tested.
         datePublished:2010-07-27T00:00:00Z
         dateModified:2010-07-27T00:00:00Z
         pageStart:183
         pageEnd:200
         sameAs:https://doi.org/10.1007/s11103-010-9665-9
         keywords:
            Chromatin remodeling
            Histone acetyltransferase
            HAT
            GCN5
            ADA2
            Plant gene regulation
            Cold acclimation
            Plant Sciences
            Biochemistry
            general
            Plant Pathology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig5_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig6_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig7_HTML.gif
         isPartOf:
            name:Plant Molecular Biology
            issn:
               1573-5028
               0167-4412
            volumeNumber:74
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Netherlands
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Kanchan Pavangadkar
               affiliation:
                     name:Michigan State University
                     address:
                        name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
                     name:Michigan State University
                     address:
                        name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Michael F. Thomashow
               affiliation:
                     name:Michigan State University
                     address:
                        name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
                     name:Michigan State University
                     address:
                        name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
                     name:Michigan State University
                     address:
                        name:MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Steven J. Triezenberg
               affiliation:
                     name:Michigan State University
                     address:
                        name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
                     name:Michigan State University
                     address:
                        name:Department of Biochemistry and Molecular Genetics, Michigan State University, East Lansing, USA
                        type:PostalAddress
                     type:Organization
                     name:Van Andel Research Institute
                     address:
                        name:Van Andel Research Institute, Grand Rapids, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Histone dynamics and roles of histone acetyltransferases during cold-induced gene regulation in Arabidopsis
      description:In Arabidopsis, CBF transcription factors bind to and activate certain cold-regulated (COR) gene promoters during cold acclimation. Consistent with the prevailing model that histone acetylation and nucleosomal depletion correspond with transcriptionally active genes, we now report that H3 acetylation increases and nucleosome occupancy decreases at COR gene promoters upon cold acclimation. Overexpression of CBF1 resulted in a constitutive increase in H3 acetylation and decrease in nucleosome occupancy, consistent with the constitutive activation of COR gene expression. Overexpression of a truncated form of CBF2 lacking its transcriptional activation domain resulted in a cold-stimulated increase in H3 acetylation, but no change in nucleosomal occupancy or COR gene expression, indicating that histone acetylation is congruent with but not sufficient for cold-activation of COR gene expression. Plants homozygous for T-DNA disruption alleles of GCN5 (encoding a histone acetyltransferase) or ADA2b (a GCN5-interacting protein) show diminished expression of COR genes during cold acclimation. Contrary to expectations, H3 acetylation at COR gene promoters was stimulated upon cold acclimation in ada2b and gcn5 plants as in wild type plants, but the decrease in nucleosome occupancy was diminished. Thus, GCN5 is not the HAT responsible for histone acetylation at COR gene promoters during cold acclimation. Several other HAT mutant plants were also tested; although some do affect COR gene expression, none affected histone acetylation. Therefore, H3 acetylation at the COR gene promoters is not solely dependent on any of the HATs tested.
      datePublished:2010-07-27T00:00:00Z
      dateModified:2010-07-27T00:00:00Z
      pageStart:183
      pageEnd:200
      sameAs:https://doi.org/10.1007/s11103-010-9665-9
      keywords:
         Chromatin remodeling
         Histone acetyltransferase
         HAT
         GCN5
         ADA2
         Plant gene regulation
         Cold acclimation
         Plant Sciences
         Biochemistry
         general
         Plant Pathology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig5_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig6_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs11103-010-9665-9/MediaObjects/11103_2010_9665_Fig7_HTML.gif
      isPartOf:
         name:Plant Molecular Biology
         issn:
            1573-5028
            0167-4412
         volumeNumber:74
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Netherlands
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Kanchan Pavangadkar
            affiliation:
                  name:Michigan State University
                  address:
                     name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
                  name:Michigan State University
                  address:
                     name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Michael F. Thomashow
            affiliation:
                  name:Michigan State University
                  address:
                     name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
                  name:Michigan State University
                  address:
                     name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
                  name:Michigan State University
                  address:
                     name:MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Steven J. Triezenberg
            affiliation:
                  name:Michigan State University
                  address:
                     name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
                  name:Michigan State University
                  address:
                     name:Department of Biochemistry and Molecular Genetics, Michigan State University, East Lansing, USA
                     type:PostalAddress
                  type:Organization
                  name:Van Andel Research Institute
                  address:
                     name:Van Andel Research Institute, Grand Rapids, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Plant Molecular Biology
      issn:
         1573-5028
         0167-4412
      volumeNumber:74
Organization:
      name:Springer Netherlands
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Michigan State University
      address:
         name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Michigan State University
      address:
         name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Michigan State University
      address:
         name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Michigan State University
      address:
         name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Michigan State University
      address:
         name:MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Michigan State University
      address:
         name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Michigan State University
      address:
         name:Department of Biochemistry and Molecular Genetics, Michigan State University, East Lansing, USA
         type:PostalAddress
      name:Van Andel Research Institute
      address:
         name:Van Andel Research Institute, Grand Rapids, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Kanchan Pavangadkar
      affiliation:
            name:Michigan State University
            address:
               name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
            name:Michigan State University
            address:
               name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
      name:Michael F. Thomashow
      affiliation:
            name:Michigan State University
            address:
               name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
            name:Michigan State University
            address:
               name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
            name:Michigan State University
            address:
               name:MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
      name:Steven J. Triezenberg
      affiliation:
            name:Michigan State University
            address:
               name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
            name:Michigan State University
            address:
               name:Department of Biochemistry and Molecular Genetics, Michigan State University, East Lansing, USA
               type:PostalAddress
            type:Organization
            name:Van Andel Research Institute
            address:
               name:Van Andel Research Institute, Grand Rapids, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
      name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
      name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
      name:Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, USA
      name:MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, USA
      name:Graduate Program in Genetics, Michigan State University, East Lansing, USA
      name:Department of Biochemistry and Molecular Genetics, Michigan State University, East Lansing, USA
      name:Van Andel Research Institute, Grand Rapids, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(233)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.33s.

LINK . SPRINGER . COM {}