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Title:
Cancer is a Preventable Disease that Requires Major Lifestyle Changes | Pharmaceutical Research
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This year, more than 1 million Americans and more than 10 million people worldwide are expected to be diagnosed with cancer, a disease commonly believed to be preventable. Only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in the environment and lifestyle. The lifestyle factors include cigarette smoking, diet (fried foods, red meat), alcohol, sun exposure, environmental pollutants, infections, stress, obesity, and physical inactivity. The evidence indicates that of all cancer-related deaths, almost 25–30% are due to tobacco, as many as 30–35% are linked to diet, about 15–20% are due to infections, and the remaining percentage are due to other factors like radiation, stress, physical activity, environmental pollutants etc. Therefore, cancer prevention requires smoking cessation, increased ingestion of fruits and vegetables, moderate use of alcohol, caloric restriction, exercise, avoidance of direct exposure to sunlight, minimal meat consumption, use of whole grains, use of vaccinations, and regular check-ups. In this review, we present evidence that inflammation is the link between the agents/factors that cause cancer and the agents that prevent it. In addition, we provide evidence that cancer is a preventable disease that requires major lifestyle changes.
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Topics {✒️}
option=com_content&task=view&isseid=48&id=6022§ionid=30&itemid=1 gov/cder/drug/infopage/cox2/nsaiddecisionmemo gov/cder/foi/appletter/1998/17970s40 gov/bbs/topics/news/2007/new01698 t8-methyl-n-vanillyl-6-nonenamide gov/nn/views/alphachron/date/10006/05/01/2008 n-nitrosodiethylamine-induced forestomach neoplasia org/docroot/stt/content/stt_1x_cancer_facts_and_figures_2008 org/docroot/cri/content/cri_2_4_2x_can_prostate_cancer_be_prevented_36 12 acetyl-11-keto-β-boswellic acid 1-methyl-1-nitrosourea-induced kidney nephroblastomas nf-κb-regulated gene expression nf-κb-regulated gene products n-nitrosomethylbenzylamine-induced esophageal cancer diethylnitrosamine-induced liver foci glutathione s-transferase activity n-acetyl-l-cysteine n-nitrosomethylbenzylamine-induced mutation nf-κb proinflammatory pathway igf/insulin/akt signaling pathway gov/ncea/cfm/recordisplay lambda-lacz-transgenic mouse human t-lymphotropic virus sustaining chemotherapy-induced damage arylamine n-acetyltransferase activity human jurkat t-cells nf-κb signaling pathway human t-cell lines org/docrep/006/y4956e/y4956e00 2-amino-1-methyl-6-phenyl-imidazo[4 adult t-cell leukemia isoflavone-rich soy-based diet 1-methyl-1-nitrosourea-initiated carcinogenesis leptin/jak/stat pathway diethylstilbesterol-induced dna adducts high-voltage power lines glutathione s-transferase cas google scholar article google scholar pubmed google scholar suppress nf-κb activation mutagenic n-nitroso compounds ebv epstein–barr virus preventing estrogen-receptor-positive dose-limiting toxic effects nf-κb inhibitory activity induces cell-cycle arrest constitutive nf-κb activation nuclear factor-kappab key risk factor
Questions {❓}
- Dietary fiber: how did we get where we are?
- Evolutionary medicine: From dwarf model systems to healthy centenarians?
- How do whole grains reduce the risk of cancer?
- Dietandcancerreportorg/?
- ” Even after an additional quarter century of extensive research, researchers are still trying to determine whether cancer is preventable and are asking “If it is preventable, why are we losing the war on cancer?
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headline:Cancer is a Preventable Disease that Requires Major Lifestyle Changes
description:This year, more than 1 million Americans and more than 10 million people worldwide are expected to be diagnosed with cancer, a disease commonly believed to be preventable. Only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in the environment and lifestyle. The lifestyle factors include cigarette smoking, diet (fried foods, red meat), alcohol, sun exposure, environmental pollutants, infections, stress, obesity, and physical inactivity. The evidence indicates that of all cancer-related deaths, almost 25–30% are due to tobacco, as many as 30–35% are linked to diet, about 15–20% are due to infections, and the remaining percentage are due to other factors like radiation, stress, physical activity, environmental pollutants etc. Therefore, cancer prevention requires smoking cessation, increased ingestion of fruits and vegetables, moderate use of alcohol, caloric restriction, exercise, avoidance of direct exposure to sunlight, minimal meat consumption, use of whole grains, use of vaccinations, and regular check-ups. In this review, we present evidence that inflammation is the link between the agents/factors that cause cancer and the agents that prevent it. In addition, we provide evidence that cancer is a preventable disease that requires major lifestyle changes.
datePublished:2008-07-15T00:00:00Z
dateModified:2008-07-15T00:00:00Z
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cancer
environmental risk factors
genetic risk factors
prevention
Pharmacology/Toxicology
Pharmacy
Biochemistry
general
Medical Law
Biomedical Engineering and Bioengineering
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headline:Cancer is a Preventable Disease that Requires Major Lifestyle Changes
description:This year, more than 1 million Americans and more than 10 million people worldwide are expected to be diagnosed with cancer, a disease commonly believed to be preventable. Only 5–10% of all cancer cases can be attributed to genetic defects, whereas the remaining 90–95% have their roots in the environment and lifestyle. The lifestyle factors include cigarette smoking, diet (fried foods, red meat), alcohol, sun exposure, environmental pollutants, infections, stress, obesity, and physical inactivity. The evidence indicates that of all cancer-related deaths, almost 25–30% are due to tobacco, as many as 30–35% are linked to diet, about 15–20% are due to infections, and the remaining percentage are due to other factors like radiation, stress, physical activity, environmental pollutants etc. Therefore, cancer prevention requires smoking cessation, increased ingestion of fruits and vegetables, moderate use of alcohol, caloric restriction, exercise, avoidance of direct exposure to sunlight, minimal meat consumption, use of whole grains, use of vaccinations, and regular check-ups. In this review, we present evidence that inflammation is the link between the agents/factors that cause cancer and the agents that prevent it. In addition, we provide evidence that cancer is a preventable disease that requires major lifestyle changes.
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environmental risk factors
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Biomedical Engineering and Bioengineering
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