We are analyzing https://link.springer.com/article/10.1007/s11064-010-0374-1.

Title:
Rostrocaudal Dynamics of CSF Biomarkers | Neurochemical Research
Description:
The rostrocaudal gradient (RCG) of markers present in cerebrospinal fluid (CSF) has not been studied adequately due to lack of appropriate control populations and ethical restrictions. The aim of this study is to understand the rostrocaudal gradient of CSF biomarkers. We contacted a study comparing CSF levels of seven biomarkers from cisternal (rostral) and lumbar (caudal) CSF obtained from patients with trigeminal neuralgia and tension-type headache. The RCGs of CSF/serum albumin ratio, 8-isoprostane. GFAP, total tau and beta amyloid protein were higher than one. The RCGs of lactate, VEGF and the heavy chain of neurofilament protein were lower than one. The study provides new values for several commonly examined markers of cisternal CSF. Knowledge of the RCG gradient of different CSF markers is important in interpreting studies reporting ventricular CSF values.
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article, google, scholar, pubmed, cas, cerebrospinal, fluid, csf, protein, neurol, markers, petzold, biomarkers, study, access, neurology, content, research, keir, lumbar, normal, privacy, cookies, analysis, rostrocaudal, tarnaris, gradient, levels, patients, tau, amyloid, lactate, ventricular, reiber, disease, data, information, publish, search, dynamics, toma, chapman, cisternal, beta, neurofilament, open, human, concentrations, spinal, log,

Topics {✒️}

month download article/chapter csf/serum albumin ratio total gamma-aminobutyric acid csf amyloid-ss levels disease-related data patterns normal subjects effects ventricular cerebrospinal fluid full article pdf commonly examined markers source-related dynamics brain-derived proteins external ventricular drainage privacy choices/manage cookies related subjects csf protein biomarkers cerebrospinal fluid levels 1007/s11064-011-0609-9 rights cerebrospinal fluid–physiology cerebrospinal fluid increase human cerebrospinal fluid serial lumbar punctures external lumbar drainage cerebrospinal fluid parameters concentration gradients homovanillic acid levels rostrocaudal gradient cerebrospinal fluid analysis neurofilament heavy chain cerebrospinal fluid diagnosis victor horsley department csf markers check access instant access article tarnaris european economic area studied adequately due tension-type headache guillain-barré syndrome braun/aesculap academia cerebrospinal fluid lactate posterior fossa amyloid conditions privacy policy differential proteomic profile neuron-specific enolase phosphorylated tau protein amyloid -protein deposition rostrocaudal dynamics csf biomarkers csf flow rate markers present

Questions {❓}

Sommer JB, Gaul C, Heckmann J, Neundorfer B, Erbguth FJ (2002) Does lumbar cerebrospinal fluid reflect ventricular cerebrospinal fluid?

Schema {🗺️}

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         headline:Rostrocaudal Dynamics of CSF Biomarkers
         description:The rostrocaudal gradient (RCG) of markers present in cerebrospinal fluid (CSF) has not been studied adequately due to lack of appropriate control populations and ethical restrictions. The aim of this study is to understand the rostrocaudal gradient of CSF biomarkers. We contacted a study comparing CSF levels of seven biomarkers from cisternal (rostral) and lumbar (caudal) CSF obtained from patients with trigeminal neuralgia and tension-type headache. The RCGs of CSF/serum albumin ratio, 8-isoprostane. GFAP, total tau and beta amyloid protein were higher than one. The RCGs of lactate, VEGF and the heavy chain of neurofilament protein were lower than one. The study provides new values for several commonly examined markers of cisternal CSF. Knowledge of the RCG gradient of different CSF markers is important in interpreting studies reporting ventricular CSF values.
         datePublished:2010-12-30T00:00:00Z
         dateModified:2010-12-30T00:00:00Z
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            Biomarkers
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            Biochemistry
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      headline:Rostrocaudal Dynamics of CSF Biomarkers
      description:The rostrocaudal gradient (RCG) of markers present in cerebrospinal fluid (CSF) has not been studied adequately due to lack of appropriate control populations and ethical restrictions. The aim of this study is to understand the rostrocaudal gradient of CSF biomarkers. We contacted a study comparing CSF levels of seven biomarkers from cisternal (rostral) and lumbar (caudal) CSF obtained from patients with trigeminal neuralgia and tension-type headache. The RCGs of CSF/serum albumin ratio, 8-isoprostane. GFAP, total tau and beta amyloid protein were higher than one. The RCGs of lactate, VEGF and the heavy chain of neurofilament protein were lower than one. The study provides new values for several commonly examined markers of cisternal CSF. Knowledge of the RCG gradient of different CSF markers is important in interpreting studies reporting ventricular CSF values.
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         Rostrocaudal gradient
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         Biomarkers
         Cisternal
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         Neurochemistry
         Biochemistry
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         Cell Biology
         Neurology
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