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LINK . SPRINGER . COM {}

  1. Analyzed Page
  2. Matching Content Categories
  3. CMS
  4. Monthly Traffic Estimate
  5. How Does Link.springer.com Make Money
  6. Keywords
  7. Topics
  8. Questions
  9. Schema
  10. External Links
  11. Analytics And Tracking
  12. Libraries
  13. CDN Services

We are analyzing https://link.springer.com/article/10.1007/s11060-013-1084-8.

Title:
Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies | Journal of Neuro-Oncology
Description:
Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular space. These extracellular vesicles (EVs) contain materials that mirror the genetic and proteomic content of the secreting cell. The identification of cancer-specific material in EVs isolated from the biofluids (e.g., serum, cerebrospinal fluid, urine) of cancer patients suggests EVs as an attractive platform for biomarker development. It is important to recognize that the EVs derived from clinical samples are likely highly heterogeneous in make-up and arose from diverse sets of biologic processes. This article aims to review the biologic processes that give rise to various types of EVs, including exosomes, microvesicles, retrovirus like particles, and apoptotic bodies. Clinical pertinence of these EVs to neuro-oncology will also be discussed.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {πŸ“š}

  • Education
  • Science
  • Telecommunications

Content Management System {πŸ“}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {πŸ“ˆ}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month


Based on our best estimate, this website will receive around 7,643,078 visitors per month in the current month.

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How Does Link.springer.com Make Money? {πŸ’Έ}

We can't figure out the monetization strategy.

The purpose of some websites isn't monetary gain; they're meant to inform, educate, or foster collaboration. Everyone has unique reasons for building websites. This could be an example. Link.springer.com might have a hidden revenue stream, but it's not something we can detect.

Keywords {πŸ”}

google, scholar, pubmed, cas, cell, human, biol, exosomes, cells, vesicles, cancer, microvesicles, endogenous, apoptotic, membrane, extracellular, bodies, retrovirus, multivesicular, nat, proteins, immunol, protein, mol, article, apoptosis, plasma, function, blood, rev, expression, hervk, particles, vesicle, budding, tetraspanin, escrt, sorting, res, content, biogenesis, gonda, chen, evs, isolation, retroviral, body, exp, med, phosphatidylserine,

Topics {βœ’οΈ}

nano-sized extra-cellular particles month download article/chapter annexin v-affinity assay dendritic cell-derived exosomes tcr/cd3/zeta complex membrane-trafficking network tetraspanin cd63/lamp3 cycles endogenous plasma-membrane proteins tumor-derived exosomes vesicle-generating organelle small vesicular culprits privacy choices/manage cookies full article pdf cell-derived exosomes human testicular tumor endogenous retrovirus derived human b-lymphocytes ceramide triggers budding cancer-specific material melanoma antigen me491 teratocarcinoma cell lines human breast cancer plasma membrane anchors plasma membrane activities plasma membrane hallmarks brain tumor exosomes provide diagnostic biomarkers programmed cell death mvb vesicle formation rat cancer model resemble retroviral vesicles activated platelets release membrane phospholipid asymmetry functional envelope protein direct outward budding human endothelial cells hurley jh alix-chmp4 interactions human endogenous retrovirus human endogenous retrovirus endothelial cells enhance related subjects primary human melanocytes melanoma cell lines endogenous retrovirus sequence author information authors european economic area vps4 atpase activity eiav p9 functioning tamm-horsfall protein

Questions {❓}

  • Samos J et al (2006) Circulating nucleic acids in plasma/serum and tumor progression: are apoptotic bodies involved?

Schema {πŸ—ΊοΈ}

WebPage:
      mainEntity:
         headline:Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies
         description:Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular space. These extracellular vesicles (EVs) contain materials that mirror the genetic and proteomic content of the secreting cell. The identification of cancer-specific material in EVs isolated from the biofluids (e.g., serum, cerebrospinal fluid, urine) of cancer patients suggests EVs as an attractive platform for biomarker development. It is important to recognize that the EVs derived from clinical samples are likely highly heterogeneous in make-up and arose from diverse sets of biologic processes. This article aims to review the biologic processes that give rise to various types of EVs, including exosomes, microvesicles, retrovirus like particles, and apoptotic bodies. Clinical pertinence of these EVs to neuro-oncology will also be discussed.
         datePublished:2013-03-02T00:00:00Z
         dateModified:2013-03-02T00:00:00Z
         pageStart:1
         pageEnd:11
         sameAs:https://doi.org/10.1007/s11060-013-1084-8
         keywords:
            Biomarkers
            Intracellular trafficking
            Membrane budding
            Tetraspanin
            Multi-vesicular bodies (MVB)
            Tumor microenvironment
            Cancer
            Oncology
            Neurology
         image:
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                        type:PostalAddress
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                        type:PostalAddress
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                     address:
                        name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
                        type:PostalAddress
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ScholarlyArticle:
      headline:Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies
      description:Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular space. These extracellular vesicles (EVs) contain materials that mirror the genetic and proteomic content of the secreting cell. The identification of cancer-specific material in EVs isolated from the biofluids (e.g., serum, cerebrospinal fluid, urine) of cancer patients suggests EVs as an attractive platform for biomarker development. It is important to recognize that the EVs derived from clinical samples are likely highly heterogeneous in make-up and arose from diverse sets of biologic processes. This article aims to review the biologic processes that give rise to various types of EVs, including exosomes, microvesicles, retrovirus like particles, and apoptotic bodies. Clinical pertinence of these EVs to neuro-oncology will also be discussed.
      datePublished:2013-03-02T00:00:00Z
      dateModified:2013-03-02T00:00:00Z
      pageStart:1
      pageEnd:11
      sameAs:https://doi.org/10.1007/s11060-013-1084-8
      keywords:
         Biomarkers
         Intracellular trafficking
         Membrane budding
         Tetraspanin
         Multi-vesicular bodies (MVB)
         Tumor microenvironment
         Cancer
         Oncology
         Neurology
      image:
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         name:Springer US
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            type:ImageObject
         type:Organization
      author:
            name:Johnny C. Akers
            affiliation:
                  name:University of California, San Diego
                  address:
                     name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
                  name:University of California, San Diego
                  address:
                     name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
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            name:David Gonda
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                  name:University of California, San Diego
                  address:
                     name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
                  name:University of California, San Diego
                  address:
                     name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ryan Kim
            affiliation:
                  name:University of California, San Diego
                  address:
                     name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
                  name:University of California, San Diego
                  address:
                     name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bob S. Carter
            affiliation:
                  name:University of California, San Diego
                  address:
                     name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
                  name:University of California, San Diego
                  address:
                     name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Clark C. Chen
            affiliation:
                  name:University of California, San Diego
                  address:
                     name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
                     type:PostalAddress
                  type:Organization
                  name:University of California, San Diego
                  address:
                     name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
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      name:University of California, San Diego
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      address:
         name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
         type:PostalAddress
      name:University of California, San Diego
      address:
         name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
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      address:
         name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
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      name:University of California, San Diego
      address:
         name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
         type:PostalAddress
      name:University of California, San Diego
      address:
         name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
         type:PostalAddress
      name:University of California, San Diego
      address:
         name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
         type:PostalAddress
      name:University of California, San Diego
      address:
         name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
         type:PostalAddress
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      name:Johnny C. Akers
      affiliation:
            name:University of California, San Diego
            address:
               name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
            name:University of California, San Diego
            address:
               name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
      name:David Gonda
      affiliation:
            name:University of California, San Diego
            address:
               name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
            name:University of California, San Diego
            address:
               name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
      name:Ryan Kim
      affiliation:
            name:University of California, San Diego
            address:
               name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
            name:University of California, San Diego
            address:
               name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
      name:Bob S. Carter
      affiliation:
            name:University of California, San Diego
            address:
               name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
            name:University of California, San Diego
            address:
               name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
      name:Clark C. Chen
      affiliation:
            name:University of California, San Diego
            address:
               name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
            name:University of California, San Diego
            address:
               name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
      name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
      name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
      name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
      name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
      name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
      name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
      name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
      name:Department of Neurosurgery, University of California, San Diego, La Jolla, USA
      name:Center for Theoretic and Applied Neuro-Oncology, University of California, San Diego, La Jolla, USA
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External Links {πŸ”—}(278)

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