We are analyzing https://link.springer.com/article/10.1007/s10863-005-6600-x.

Title:
Mitochondria and Endoplasmic Reticulum: The Lethal Interorganelle Cross-Talk | Journal of Bioenergetics and Biomembranes
Description:
The fundamental contribution of the mitochondria and ER to the decision made on the cell’s fate has been increasingly recognized. This progress has illuminated the need for the mechanisms these organelles use to initiate and to propagate apoptotic signals. The toolbox of the mitochondria and ER is evolutionary conserved, overlapping and complementary. Furthermore, mitochondria are often closely associated with the ER providing the conditions for a local and privileged communication between the two organelles. The present review is concerned with the spatially and temporally coordinated utilization of Bcl-2 family proteins and Ca2+ by the mitochondria and ER to control the membrane permeabilization in the mitochondria and to regulate Ca2+ distribution and the activity of apoptotic proteins in the ER. The apoptotic means of the mitochondria and ER will eventually come together to control the dismantling of the cell by the caspases and other enzymes.
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Keywords {🔍}

google, scholar, pubmed, article, biol, cell, chem, mol, mitochondria, korsmeyer, embo, science, shore, hajnoczky, biophys, biochem, nature, sci, pozzan, reed, thomas, kroemer, oncogene, scorrano, usa, privacy, cookies, content, journal, hajnóczky, access, green, bioenerg, biomembr, proc, natl, acad, germain, mathai, rizzuto, haworth, hunter, wang, publish, search, endoplasmic, györgy, proteins, calcium, biochim,

Topics {✒️}

lethal interorganelle cross-talk month download article/chapter er-mitochondria calcium transfer pubmed google scholar bcl-2 family proteins related subjects full article pdf privacy choices/manage cookies article walter endoplasmic reticulum er european economic area temporally coordinated utilization györgy hajnóczky regulate ca2+ distribution propagate apoptotic signals check access instant access accepting optional cookies journal finder publish conditions privacy policy article journal main content log thomas jefferson university apoptotic proteins endoplasmic reticulum author correspondence article log privileged communication article cite cell death differ organelle contacts de smedt de camilli privacy policy personal data cell calcium 28 cell calcium 32 affiliations department books a optional cookies manage preferences er providing death differ journal publish data protection essential cookies cookies skip subscription content similar content biomembranes aims

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         description:The fundamental contribution of the mitochondria and ER to the decision made on the cell’s fate has been increasingly recognized. This progress has illuminated the need for the mechanisms these organelles use to initiate and to propagate apoptotic signals. The toolbox of the mitochondria and ER is evolutionary conserved, overlapping and complementary. Furthermore, mitochondria are often closely associated with the ER providing the conditions for a local and privileged communication between the two organelles. The present review is concerned with the spatially and temporally coordinated utilization of Bcl-2 family proteins and Ca2+ by the mitochondria and ER to control the membrane permeabilization in the mitochondria and to regulate Ca2+ distribution and the activity of apoptotic proteins in the ER. The apoptotic means of the mitochondria and ER will eventually come together to control the dismantling of the cell by the caspases and other enzymes.
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