We are analyzing https://link.springer.com/article/10.1007/s10557-008-6084-0.

Title:
Medium-chain Fatty Acids as Metabolic Therapy in Cardiac Disease | Cardiovascular Drugs and Therapy
Description:
Introduction Medium-chain fatty acids (MCFAs) have physical and metabolic properties that are distinct from those of long-chain fatty acids, which make them a readily available cellular energy source. These properties have been used advantageously in the clinics for more than 50 years for treating lipid absorption disorders, undernourished patients, and more recently subjects with long-chain fatty acid oxidation defects. In these latter subjects, nutritional interventions with MCFA-containing triglycerides have been shown to improve clinical symptoms, particularly cardiomyopathies. Potential benefits of MCFA metabolism in cardiac diseases There is, however, only a limited number of studies that have considered the potential use of MCFAs as metabolic therapy for cardiac diseases in general. Nevertheless, current experimental evidence does support the notion that the diseased heart is energy deficient and that alterations in myocardial energy substrate metabolism contribute to contractile dysfunction and cardiac disease development and progression. Hence, this article will review current literature on MCFAs with a specific emphasis on their metabolism and potential benefits for the heart. It will include practical considerations about the potential clinical application of MCFA therapy for the management of patients with cardiac diseases.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Health & Fitness
Education
Fitness & Wellness

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We can't see how the site brings in money.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Link.springer.com has a secret sauce for making money, but we can't detect it yet.

Keywords {🔍}

google, scholar, pubmed, cas, article, fatty, heart, physiol, acid, mediumchain, oxidation, metabolism, cardiac, acids, nutr, dehydrogenase, metabolic, deficiency, clin, effects, rosiers, longchain, triglyceride, triglycerides, metab, rat, therapy, myocardial, substrate, mitochondrial, medium, chain, biochem, hearts, circ, disorders, treatment, dis, diet, montreal, content, research, disease, energy, lipid, access, dietary, fat, pharmacol, privacy,

Topics {✒️}

side-chain length-specific manner medium-chain-triglyceride lipid emulsion month download article/chapter long-chain fatty acids medium-chain fatty acid medium-chain fatty acids long-chain 3-hydroxyacyl-coenzyme long-chain acyl-coenzyme alpha-lipoic acid diet medium-chain triglyceride formulas medium-chain triglyceride feeding g-protein-coupled receptors long-chain triglycerides labeled dietary saturated fats medium-chain triglyceride treatment calcium-induced workload transitions dietary medium-chain triglycerides anaplerotic odd-chain triglyceride ppar alpha-mediated lipotoxicity carnitine-acylcarnitine translocase deficiency 3-hydroxy-fatty acids article cardiovascular drugs fatty acid oxidation palmitate-perfused rat hearts medium chain triglyceride medium-chain triglyceride cardiomyopathic heart failure fatty acyl coenzyme long chain triglycerides cardiac disease published cardiac disease development providing 13c-labelled heptanoate christine des rosiers fatty acid supply full article pdf medium-chain triglycerides medium chain triglycerides coronary heart disease privacy choices/manage cookies coagulation pathways growing receptor family high-fat diet myocardial substrate metabolism okere ic myocardial substrate selection cardiac substrate uptake metabolic therapy cellular energy source article labarthe perfused rat heart

Questions {❓}

Does an anaplerotic substrate protect the ischaemic myocardium?
No low-fat diet for the failing heart?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Medium-chain Fatty Acids as Metabolic Therapy in Cardiac Disease
         description:Medium-chain fatty acids (MCFAs) have physical and metabolic properties that are distinct from those of long-chain fatty acids, which make them a readily available cellular energy source. These properties have been used advantageously in the clinics for more than 50 years for treating lipid absorption disorders, undernourished patients, and more recently subjects with long-chain fatty acid oxidation defects. In these latter subjects, nutritional interventions with MCFA-containing triglycerides have been shown to improve clinical symptoms, particularly cardiomyopathies. There is, however, only a limited number of studies that have considered the potential use of MCFAs as metabolic therapy for cardiac diseases in general. Nevertheless, current experimental evidence does support the notion that the diseased heart is energy deficient and that alterations in myocardial energy substrate metabolism contribute to contractile dysfunction and cardiac disease development and progression. Hence, this article will review current literature on MCFAs with a specific emphasis on their metabolism and potential benefits for the heart. It will include practical considerations about the potential clinical application of MCFA therapy for the management of patients with cardiac diseases.
         datePublished:2008-02-06T00:00:00Z
         dateModified:2008-02-06T00:00:00Z
         pageStart:97
         pageEnd:106
         sameAs:https://doi.org/10.1007/s10557-008-6084-0
         keywords:
            medium-chain fatty acid
            heart
            cardiomyopathy
            metabolism
            energy
            nutrition
            Cardiology
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig4_HTML.gif
         isPartOf:
            name:Cardiovascular Drugs and Therapy
            issn:
               1573-7241
               0920-3206
            volumeNumber:22
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:François Labarthe
               affiliation:
                     name:Université François Rabelais, INSERM E211
                     address:
                        name:CHRU de Tours, Université François Rabelais, INSERM E211, Tours, France
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Roselle Gélinas
               affiliation:
                     name:University of Montreal and Montreal Heart Institute
                     address:
                        name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Christine Des Rosiers
               affiliation:
                     name:University of Montreal and Montreal Heart Institute
                     address:
                        name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
                        type:PostalAddress
                     type:Organization
                     name:Montreal Heart Institute Research Center
                     address:
                        name:Laboratory of Intermediary Metabolism, Montreal Heart Institute Research Center, Montreal, Canada
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Medium-chain Fatty Acids as Metabolic Therapy in Cardiac Disease
      description:Medium-chain fatty acids (MCFAs) have physical and metabolic properties that are distinct from those of long-chain fatty acids, which make them a readily available cellular energy source. These properties have been used advantageously in the clinics for more than 50 years for treating lipid absorption disorders, undernourished patients, and more recently subjects with long-chain fatty acid oxidation defects. In these latter subjects, nutritional interventions with MCFA-containing triglycerides have been shown to improve clinical symptoms, particularly cardiomyopathies. There is, however, only a limited number of studies that have considered the potential use of MCFAs as metabolic therapy for cardiac diseases in general. Nevertheless, current experimental evidence does support the notion that the diseased heart is energy deficient and that alterations in myocardial energy substrate metabolism contribute to contractile dysfunction and cardiac disease development and progression. Hence, this article will review current literature on MCFAs with a specific emphasis on their metabolism and potential benefits for the heart. It will include practical considerations about the potential clinical application of MCFA therapy for the management of patients with cardiac diseases.
      datePublished:2008-02-06T00:00:00Z
      dateModified:2008-02-06T00:00:00Z
      pageStart:97
      pageEnd:106
      sameAs:https://doi.org/10.1007/s10557-008-6084-0
      keywords:
         medium-chain fatty acid
         heart
         cardiomyopathy
         metabolism
         energy
         nutrition
         Cardiology
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10557-008-6084-0/MediaObjects/10557_2008_6084_Fig4_HTML.gif
      isPartOf:
         name:Cardiovascular Drugs and Therapy
         issn:
            1573-7241
            0920-3206
         volumeNumber:22
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:François Labarthe
            affiliation:
                  name:Université François Rabelais, INSERM E211
                  address:
                     name:CHRU de Tours, Université François Rabelais, INSERM E211, Tours, France
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Roselle Gélinas
            affiliation:
                  name:University of Montreal and Montreal Heart Institute
                  address:
                     name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Christine Des Rosiers
            affiliation:
                  name:University of Montreal and Montreal Heart Institute
                  address:
                     name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
                     type:PostalAddress
                  type:Organization
                  name:Montreal Heart Institute Research Center
                  address:
                     name:Laboratory of Intermediary Metabolism, Montreal Heart Institute Research Center, Montreal, Canada
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Cardiovascular Drugs and Therapy
      issn:
         1573-7241
         0920-3206
      volumeNumber:22
Organization:
      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Université François Rabelais, INSERM E211
      address:
         name:CHRU de Tours, Université François Rabelais, INSERM E211, Tours, France
         type:PostalAddress
      name:University of Montreal and Montreal Heart Institute
      address:
         name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
         type:PostalAddress
      name:University of Montreal and Montreal Heart Institute
      address:
         name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
         type:PostalAddress
      name:Montreal Heart Institute Research Center
      address:
         name:Laboratory of Intermediary Metabolism, Montreal Heart Institute Research Center, Montreal, Canada
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:François Labarthe
      affiliation:
            name:Université François Rabelais, INSERM E211
            address:
               name:CHRU de Tours, Université François Rabelais, INSERM E211, Tours, France
               type:PostalAddress
            type:Organization
      name:Roselle Gélinas
      affiliation:
            name:University of Montreal and Montreal Heart Institute
            address:
               name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
               type:PostalAddress
            type:Organization
      name:Christine Des Rosiers
      affiliation:
            name:University of Montreal and Montreal Heart Institute
            address:
               name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
               type:PostalAddress
            type:Organization
            name:Montreal Heart Institute Research Center
            address:
               name:Laboratory of Intermediary Metabolism, Montreal Heart Institute Research Center, Montreal, Canada
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:CHRU de Tours, Université François Rabelais, INSERM E211, Tours, France
      name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
      name:Department of Nutrition, University of Montreal and Montreal Heart Institute, Montreal, Canada
      name:Laboratory of Intermediary Metabolism, Montreal Heart Institute Research Center, Montreal, Canada
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(228)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Foundation
Prism.js

CDN Services {📦}

Crossref

5.38s.

LINK . SPRINGER . COM {}