We are analyzing https://link.springer.com/article/10.1007/s10555-023-10154-7.

Title:
Targeting vimentin: a multifaceted approach to combatting cancer metastasis and drug resistance | Cancer and Metastasis Reviews
Description:
This comprehensive review explores vimentin as a pivotal therapeutic target in cancer treatment, with a primary focus on mitigating metastasis and overcoming drug resistance. Vimentin, a key player in cancer progression, is intricately involved in processes such as epithelial-to-mesenchymal transition (EMT) and resistance mechanisms to standard cancer therapies. The review delves into diverse vimentin inhibition strategies. Precision tools, including antibodies and nanobodies, selectively neutralize vimentin
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28 years and 1 months (reg. 1997-05-29).

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Keywords {🔍}

pubmed, google, scholar, cancer, cas, article, vimentin, central, cell, journal, cells, wang, transition, metastasis, molecular, tumor, research, httpsdoiorgs, resistance, therapy, epithelialmesenchymal, liu, sciences, emt, plasticity, chen, breast, targeting, therapeutic, oncology, invasion, science, review, nature, epithelial, expression, intermediate, target, aptamers, zhang, human, treatment, mechanisms, targeted, lung, filaments, regulates, content, data, drug,

Topics {✒️}

oncogenic wnt/β-catenin/bcl9 pathway mir-30a/nf-κb/snail signaling month download article/chapter microrna-30c promotes invasion graphene oxide nano-complex microrna-17-5p regulates emt mirna-based therapeutic intervention vimentin-targeting oral compound vimentin-binding aptamer motifs n-ras proto-oncogenes increases chemotherapy sensitivity targeted personalized therapies exerts anti-metastatic activity writing—original draft preparation intra-filament subunit organization mir-dependent negative regulation harnessing epithelial-mesenchymal plasticity emt-inducing transcription factors cancer stem cells—origins facilitates sars-cov-2 entry nf-κb inhibitor therapy resistant access single-cell transcriptomics promising anti-cancer approach sequential met-tki treatment dna-aptamer targeting vimentin site-specific glycosylation regulates full article pdf circular rna circtubgcp3 standard cancer therapies renal cell carcinoma pancreatic ductal adenocarcinoma vimentin-targeted vaccines anti-angiogenic immunotherapy plasminogen activator system promotes cell proliferation oncogenic signaling pathways privacy choices/manage cookies microrna-based therapeutics facilitates early metastasis anti-metastasis therapy post-transcriptional regulation tissue factor mrna epithelial-mesenchymal transition epithelial mesenchymal transition epithelial–mesenchymal transition adaptable binding properties tumour cell lines investigating citrullinated proteins previously published data

Questions {❓}

EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: The two sides of the same coin?

Schema {🗺️}

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