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Title:
Adolescent dietary phytoestrogen intake and breast cancer risk (Canada) | Cancer Causes & Control
Description:
It has been suggested that dietary phytoestrogen intake during adolescence may reduce the risk of developing breast cancer. This population-based caseācontrol study evaluated the association between adolescent dietary phytoestrogen intake and adult breast cancer risk among women in Ontario, Canada. Pathology-confirmed, population-based breast cancer cases, aged 25ā74 years, diagnosed between June 2002 and April 2003, were identified using the Ontario Cancer Registry. Population-based controls were recruited, and matched to cases within 5-year age groups. Adolescent phytoestrogen intake was obtained using a brief food frequency questionnaire (n = 3,024 cases, n = 3,420 controls). Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Higher phytoestrogen intake (both isoflavones and lignans) during adolescence was associated with a reduced breast cancer risk, and a monotonic trend was observed from the lowest to the highest quartile (OR [Q2] = 0.91, 95% CI 0.79ā1.04, OR[Q3] = 0.86, 95% CI 0.75ā0.98, and OR[Q4] = 0.71, 95% CI 0.62ā0.82, p-trend < 0.001). Adolescent dietary phytoestrogen intake may be associated with a decreased risk of adult breast cancer. If verified, this finding has important implications with regard to breast cancer prevention since diet is a potentially modifiable factor.
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Keywords {š}
cancer, google, scholar, cas, pubmed, article, breast, risk, nutr, dietary, intake, phytoestrogen, adolescent, diet, soy, study, mammary, content, lignan, control, health, epidemiol, exposure, thompson, women, food, genistein, clin, mazur, beans, adlercreutz, high, phytoestrogens, cereals, data, canada, cotterchio, kreiger, adolescence, isoflavones, lignans, prevention, gland, low, bread, white, juice, privacy, cookies, research,
Topics {āļø}
dried apricots/prunes/dates/figs 12-dimethyl9a-anthracene-induced mammary carcinogenesis month download article/chapter population-based caseācontrol study chemically-induced mammary cancer dmba-induced mammary cancer block98 food-frequency questionnaire de kleijn mj chick peas/garbanzo beans rat mammary gland full article pdf mammary gland morphogenesis breast cancer prevention privacy choices/manage cookies food frequency questionnaire food-frequency questionnaire caseācontrol study population-based controls dietary phytoestrogen intake spontaneous mammary tumors naturally occurring oestrogens established risk factors adolescent phytoestrogen intake mammary gland development van de putte multi-ethnic population enhances gland differentiation dietary phytochemical index murrill wb recent eating patterns special funding support raisins/dried currants related subjects developing breast cancer female breast cancer breast cancer survivors article thanos adult breast cancer ontario cancer registry cancer care ontario estimate odds ratios article cancer genistein induces maturation breast cancer cases postmenopausal breast cancer green beans/peas breast cancer risk european economic area 5-year age groups potentially modifiable factor
Questions {ā}
- Bingham SA, Atkinson C, Liggins J, Bluck L, Coward A (1998) Phyto-oestrogens: where are we now?
- Schedin PJ, Byers T (1997) Adolescent diet and the risk of breast cancer in adulthood: a role for vitamin A?
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headline:Adolescent dietary phytoestrogen intake and breast cancer risk (Canada)
description:It has been suggested that dietary phytoestrogen intake during adolescence may reduce the risk of developing breast cancer. This population-based caseācontrol study evaluated the association between adolescent dietary phytoestrogen intake and adult breast cancer risk among women in Ontario, Canada. Pathology-confirmed, population-based breast cancer cases, aged 25ā74Ā years, diagnosed between June 2002 and April 2003, were identified using the Ontario Cancer Registry. Population-based controls were recruited, and matched to cases within 5-year age groups. Adolescent phytoestrogen intake was obtained using a brief food frequency questionnaire (nĀ =Ā 3,024 cases, nĀ =Ā 3,420 controls). Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Higher phytoestrogen intake (both isoflavones and lignans) during adolescence was associated with a reduced breast cancer risk, and a monotonic trend was observed from the lowest to the highest quartile (OR [Q2]Ā =Ā 0.91, 95% CI 0.79ā1.04, OR[Q3]Ā =Ā 0.86, 95% CI 0.75ā0.98, and OR[Q4]Ā =Ā 0.71, 95% CI 0.62ā0.82, p-trendĀ <Ā 0.001). Adolescent dietary phytoestrogen intake may be associated with a decreased risk of adult breast cancer. If verified, this finding has important implications with regard to breast cancer prevention since diet is a potentially modifiable factor.
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Phytoestrogen
Adolescence
Breast cancer
Dietary intake
Prevention
Cancer Research
Biomedicine
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Public Health
Epidemiology
Hematology
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headline:Adolescent dietary phytoestrogen intake and breast cancer risk (Canada)
description:It has been suggested that dietary phytoestrogen intake during adolescence may reduce the risk of developing breast cancer. This population-based caseācontrol study evaluated the association between adolescent dietary phytoestrogen intake and adult breast cancer risk among women in Ontario, Canada. Pathology-confirmed, population-based breast cancer cases, aged 25ā74Ā years, diagnosed between June 2002 and April 2003, were identified using the Ontario Cancer Registry. Population-based controls were recruited, and matched to cases within 5-year age groups. Adolescent phytoestrogen intake was obtained using a brief food frequency questionnaire (nĀ =Ā 3,024 cases, nĀ =Ā 3,420 controls). Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Higher phytoestrogen intake (both isoflavones and lignans) during adolescence was associated with a reduced breast cancer risk, and a monotonic trend was observed from the lowest to the highest quartile (OR [Q2]Ā =Ā 0.91, 95% CI 0.79ā1.04, OR[Q3]Ā =Ā 0.86, 95% CI 0.75ā0.98, and OR[Q4]Ā =Ā 0.71, 95% CI 0.62ā0.82, p-trendĀ <Ā 0.001). Adolescent dietary phytoestrogen intake may be associated with a decreased risk of adult breast cancer. If verified, this finding has important implications with regard to breast cancer prevention since diet is a potentially modifiable factor.
datePublished:
dateModified:
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pageEnd:1261
sameAs:https://doi.org/10.1007/s10552-006-0062-2
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Phytoestrogen
Adolescence
Breast cancer
Dietary intake
Prevention
Cancer Research
Biomedicine
general
Oncology
Public Health
Epidemiology
Hematology
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