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Title:
Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women | Breast Cancer Research and Treatment
Description:
Purpose Lymphedema of the arm is a potential complication of breast cancer therapy. This study examines pre-disposing factors that may operate in conjunction with treatment-related factors in the development of arm lymphedema in a large cohort of White and Black breast cancer survivors. Methods 494 women (271 White and 223 Black) with in situ to Stage III-A primary breast cancer completed a baseline interview within 18 months of diagnosis. Information on lymphedema was collected during a follow-up interview, conducted on average 50 months after diagnosis. Self-reported data were used to classify women with or without lymphedema. Multivariable logistic regression models were developed to identify risk factors for arm lymphedema. Results Arm lymphedema was associated with younger age at diagnosis (odds ratio, OR per year of age = 0.96; 95% confidence interval, CI = 0.93ā0.99), positive history of hypertension (OR = 2.31; 95% CI = 1.38ā3.88), obesity (OR for body mass index, BMIā„30 = 2.48; 95% CI = 1.05ā5.84) and having had surgery where 10 or more lymph nodes were excised (OR = 2.16; 95% CI = 1.12ā4.17). While Black women had higher prevalence of arm lymphedema than White women (28% vs. 21%), race was not associated with lymphedema risk in models adjusted for multiple factors (adjusted OR = 1.01; 95% CI = 0.63ā1.63). Conclusion Risk of arm lymphedema did not differ significantly for Black and White women. Risk factors identified in this study offer opportunities for interventions (weight loss, control of blood pressure, use of sentinel node biopsy where possible) for reducing incidence of lymphedema or controlling the symptoms associated with this condition.
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cancer, breast, google, scholar, article, pubmed, lymphedema, cas, arm, factors, risk, oncol, treatment, patients, women, research, study, surg, survivors, black, node, health, diagnosis, white, hypertension, axillary, morbidity, carcinoma, national, usa, privacy, cookies, content, data, february, meeske, development, surgery, lymph, cancerrelated, dissection, quality, life, lymphoedema, nurs, california, department, information, publish, search,
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month download article/chapter jane sullivan-halley sentinel node biopsy early-stage breast cancer breast cancer-related lymphedema ii axillary dissection body mass index stage i-ii carcinoma full article pdf leslie bernstein privacy choices/manage cookies treatment-related factors related subjects breast cancer therapy breast cancer survivor national cancer institute breast cancer patients identify risk factors risk factors identified breast cancer surgery comprehensive cancer center breast cancer treatment randomized controlled trial sullivan-halley breast cancer patient breast conservation therapy chronic breast lymphedema study offer opportunities framingham offspring study breast carcinoma irradiation breast conserving treatment breast cancer diagnosis european economic area complete decongestive therapy human physical activities lymph nodes patients treated conservatively reproductive experiences study upper extremity lymphedema conditions privacy policy regional nodal irradiation 5-year prospective study major predictive factor post-treatment symptoms axillary surgery accepting optional cookies updated systematic review article log chronic arm morbidity transdisciplinary research
Questions {ā}
- Soran A, DāAngelo G, Begovic M et al (2006) Breast cancer-related lymphedema ā What are the significant predictors and how do they affect the severity of lymphedema?
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headline:Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women
description:
Purpose Lymphedema of the arm is a potential complication of breast cancer therapy. This study examines pre-disposing factors that may operate in conjunction with treatment-related factors in the development of arm lymphedema in a large cohort of White and Black breast cancer survivors. Methods 494 women (271 White and 223 Black) with in situ to Stage III-A primary breast cancer completed a baseline interview within 18Ā months of diagnosis. Information on lymphedema was collected during a follow-up interview, conducted on average 50Ā months after diagnosis. Self-reported data were used to classify women with or without lymphedema. Multivariable logistic regression models were developed to identify risk factors for arm lymphedema. Results Arm lymphedema was associated with younger age at diagnosis (odds ratio, OR per year of ageĀ =Ā 0.96; 95% confidence interval, CIĀ =Ā 0.93ā0.99), positive history of hypertension (ORĀ =Ā 2.31; 95% CIĀ =Ā 1.38ā3.88), obesity (OR for body mass index, BMIā„30Ā =Ā 2.48; 95% CIĀ =Ā 1.05ā5.84) and having had surgery where 10 or more lymph nodes were excised (ORĀ =Ā 2.16; 95% CIĀ =Ā 1.12ā4.17). While Black women had higher prevalence of arm lymphedema than White women (28% vs. 21%), race was not associated with lymphedema risk in models adjusted for multiple factors (adjusted ORĀ =Ā 1.01; 95% CIĀ =Ā 0.63ā1.63). Conclusion Risk of arm lymphedema did not differ significantly for Black and White women. Risk factors identified in this study offer opportunities for interventions (weight loss, control of blood pressure, use of sentinel node biopsy where possible) for reducing incidence of lymphedema or controlling the symptoms associated with this condition.
datePublished:2008-02-24T00:00:00Z
dateModified:2008-02-24T00:00:00Z
pageStart:383
pageEnd:391
sameAs:https://doi.org/10.1007/s10549-008-9940-5
keywords:
Breast cancer survivors
Black breast cancer survivors
Arm lymphedema
Risk factors for arm lymphedema
Hypertension
Body mass index
Race
Oncology
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headline:Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women
description:
Purpose Lymphedema of the arm is a potential complication of breast cancer therapy. This study examines pre-disposing factors that may operate in conjunction with treatment-related factors in the development of arm lymphedema in a large cohort of White and Black breast cancer survivors. Methods 494 women (271 White and 223 Black) with in situ to Stage III-A primary breast cancer completed a baseline interview within 18Ā months of diagnosis. Information on lymphedema was collected during a follow-up interview, conducted on average 50Ā months after diagnosis. Self-reported data were used to classify women with or without lymphedema. Multivariable logistic regression models were developed to identify risk factors for arm lymphedema. Results Arm lymphedema was associated with younger age at diagnosis (odds ratio, OR per year of ageĀ =Ā 0.96; 95% confidence interval, CIĀ =Ā 0.93ā0.99), positive history of hypertension (ORĀ =Ā 2.31; 95% CIĀ =Ā 1.38ā3.88), obesity (OR for body mass index, BMIā„30Ā =Ā 2.48; 95% CIĀ =Ā 1.05ā5.84) and having had surgery where 10 or more lymph nodes were excised (ORĀ =Ā 2.16; 95% CIĀ =Ā 1.12ā4.17). While Black women had higher prevalence of arm lymphedema than White women (28% vs. 21%), race was not associated with lymphedema risk in models adjusted for multiple factors (adjusted ORĀ =Ā 1.01; 95% CIĀ =Ā 0.63ā1.63). Conclusion Risk of arm lymphedema did not differ significantly for Black and White women. Risk factors identified in this study offer opportunities for interventions (weight loss, control of blood pressure, use of sentinel node biopsy where possible) for reducing incidence of lymphedema or controlling the symptoms associated with this condition.
datePublished:2008-02-24T00:00:00Z
dateModified:2008-02-24T00:00:00Z
pageStart:383
pageEnd:391
sameAs:https://doi.org/10.1007/s10549-008-9940-5
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Breast cancer survivors
Black breast cancer survivors
Arm lymphedema
Risk factors for arm lymphedema
Hypertension
Body mass index
Race
Oncology
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