We are analyzing https://link.springer.com/article/10.1007/s10549-007-9683-8.

Title:
Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors | Breast Cancer Research and Treatment
Description:
We examined the association between post-diagnosis statin use (3-hydroxy-3-methylglutaryl-coenzyme A [HMG-CoA] inhibitors) and risk of breast cancer recurrence. The study included 1945 early stage breast cancer survivors participating in the Life After Cancer Epidemiology (LACE) Study. Women who were diagnosed from 1997 to 2000 and identified from the Kaiser Permanente Northern California (KPNC) Cancer Registry entered the cohort on average 2 years post-diagnosis. Information on statin use was obtained from the KPNC pharmacy database. A total of 210 breast cancer recurrences were reported and verified by medical record review. Cox proportional hazard models were used to estimate rate ratios (RR) and 95% confidence intervals (CI). The mean duration of statin use in the cohort among those who initiated use post-diagnosis was 1.96 years, and lipophilic statins were mainly used (97.8%). Starting statins after diagnosis was suggestive of a decreased risk of breast cancer recurrence (RR = 0.67; 95% CI: 0.39–1.13). Risk of recurrence decreased with increasing duration of statin use after diagnosis (p linear trend = 0.02). Our findings provide initial support for an inverse association between post-diagnosis, lipophilic statin use and risk of breast cancer recurrence.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Health & Fitness
Education
Insurance

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure how the site profits.

While profit motivates many websites, others exist to inspire, entertain, or provide valuable resources. Websites have a variety of goals. And this might be one of them. Link.springer.com might be making money, but it's not detectable how they're doing it.

Keywords {🔍}

cancer, breast, article, google, scholar, pubmed, statins, risk, statin, cas, study, clin, research, recurrence, oncol, postdiagnosis, cohort, privacy, cookies, content, data, support, access, author, information, publish, search, treatment, prospective, early, stage, survivors, epidemiology, kwan, association, analysis, log, journal, marilyn, habel, flick, quesenberry, caan, lace, kaiser, permanente, lipophilic, survival, therapy, clinical,

Topics {✒️}

[hmg-coa] inhibitors long-term lipid-lowering therapy month download article/chapter quesenberry & bette caan population-based cohort study average 2 years post-diagnosis full article pdf breast cancer recurrence privacy choices/manage cookies related subjects prospective meta-analysis lipid-lowering drugs breast cancer inhibition breast cancer subtypes breast cancer incidence human receptor-positive mammary carcinoma cells de lorenzo ms medical record review breast cancer risk cancer registry entered national cancer institute breast carcinoma risk statistical programming support applied survival analysis european economic area 3-hydroxy-3-methylglutaryl-coenzyme estimate rate ratios 3-hydroxy-3-methylglutaryl conenzyme farina hg utah cancer registry cholesterol-lowering treatment case-control study case control study conditions privacy policy kpnc pharmacy database prospective cohort study womens health initiative inhibits experimental metastasis sentara health plan author information authors meta-analysis lace study staff accepting optional cookies check access alonso df instant access article log randomized clinical trials breast cancer

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors
         description:We examined the association between post-diagnosis statin use (3-hydroxy-3-methylglutaryl-coenzyme A [HMG-CoA] inhibitors) and risk of breast cancer recurrence. The study included 1945 early stage breast cancer survivors participating in the Life After Cancer Epidemiology (LACE) Study. Women who were diagnosed from 1997 to 2000 and identified from the Kaiser Permanente Northern California (KPNC) Cancer Registry entered the cohort on average 2 years post-diagnosis. Information on statin use was obtained from the KPNC pharmacy database. A total of 210 breast cancer recurrences were reported and verified by medical record review. Cox proportional hazard models were used to estimate rate ratios (RR) and 95% confidence intervals (CI). The mean duration of statin use in the cohort among those who initiated use post-diagnosis was 1.96 years, and lipophilic statins were mainly used (97.8%). Starting statins after diagnosis was suggestive of a decreased risk of breast cancer recurrence (RR = 0.67; 95% CI: 0.39–1.13). Risk of recurrence decreased with increasing duration of statin use after diagnosis (p linear trend = 0.02). Our findings provide initial support for an inverse association between post-diagnosis, lipophilic statin use and risk of breast cancer recurrence.
         datePublished:2007-08-03T00:00:00Z
         dateModified:2007-08-03T00:00:00Z
         pageStart:573
         pageEnd:579
         sameAs:https://doi.org/10.1007/s10549-007-9683-8
         keywords:
            Statins
            HMG-CoA inhibitors
            Breast cancer
            Recurrence
            Prognosis
            Oncology
         image:
         isPartOf:
            name:Breast Cancer Research and Treatment
            issn:
               1573-7217
               0167-6806
            volumeNumber:109
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer US
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Marilyn L. Kwan
               affiliation:
                     name:Kaiser Permanente
                     address:
                        name:Division of Research, Kaiser Permanente, Oakland, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Laurel A. Habel
               affiliation:
                     name:Kaiser Permanente
                     address:
                        name:Division of Research, Kaiser Permanente, Oakland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:E. Dawn Flick
               affiliation:
                     name:Kaiser Permanente
                     address:
                        name:Division of Research, Kaiser Permanente, Oakland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Charles P. Quesenberry
               affiliation:
                     name:Kaiser Permanente
                     address:
                        name:Division of Research, Kaiser Permanente, Oakland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bette Caan
               affiliation:
                     name:Kaiser Permanente
                     address:
                        name:Division of Research, Kaiser Permanente, Oakland, USA
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors
      description:We examined the association between post-diagnosis statin use (3-hydroxy-3-methylglutaryl-coenzyme A [HMG-CoA] inhibitors) and risk of breast cancer recurrence. The study included 1945 early stage breast cancer survivors participating in the Life After Cancer Epidemiology (LACE) Study. Women who were diagnosed from 1997 to 2000 and identified from the Kaiser Permanente Northern California (KPNC) Cancer Registry entered the cohort on average 2 years post-diagnosis. Information on statin use was obtained from the KPNC pharmacy database. A total of 210 breast cancer recurrences were reported and verified by medical record review. Cox proportional hazard models were used to estimate rate ratios (RR) and 95% confidence intervals (CI). The mean duration of statin use in the cohort among those who initiated use post-diagnosis was 1.96 years, and lipophilic statins were mainly used (97.8%). Starting statins after diagnosis was suggestive of a decreased risk of breast cancer recurrence (RR = 0.67; 95% CI: 0.39–1.13). Risk of recurrence decreased with increasing duration of statin use after diagnosis (p linear trend = 0.02). Our findings provide initial support for an inverse association between post-diagnosis, lipophilic statin use and risk of breast cancer recurrence.
      datePublished:2007-08-03T00:00:00Z
      dateModified:2007-08-03T00:00:00Z
      pageStart:573
      pageEnd:579
      sameAs:https://doi.org/10.1007/s10549-007-9683-8
      keywords:
         Statins
         HMG-CoA inhibitors
         Breast cancer
         Recurrence
         Prognosis
         Oncology
      image:
      isPartOf:
         name:Breast Cancer Research and Treatment
         issn:
            1573-7217
            0167-6806
         volumeNumber:109
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer US
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Marilyn L. Kwan
            affiliation:
                  name:Kaiser Permanente
                  address:
                     name:Division of Research, Kaiser Permanente, Oakland, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Laurel A. Habel
            affiliation:
                  name:Kaiser Permanente
                  address:
                     name:Division of Research, Kaiser Permanente, Oakland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:E. Dawn Flick
            affiliation:
                  name:Kaiser Permanente
                  address:
                     name:Division of Research, Kaiser Permanente, Oakland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Charles P. Quesenberry
            affiliation:
                  name:Kaiser Permanente
                  address:
                     name:Division of Research, Kaiser Permanente, Oakland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bette Caan
            affiliation:
                  name:Kaiser Permanente
                  address:
                     name:Division of Research, Kaiser Permanente, Oakland, USA
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Breast Cancer Research and Treatment
      issn:
         1573-7217
         0167-6806
      volumeNumber:109
Organization:
      name:Springer US
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Kaiser Permanente
      address:
         name:Division of Research, Kaiser Permanente, Oakland, USA
         type:PostalAddress
      name:Kaiser Permanente
      address:
         name:Division of Research, Kaiser Permanente, Oakland, USA
         type:PostalAddress
      name:Kaiser Permanente
      address:
         name:Division of Research, Kaiser Permanente, Oakland, USA
         type:PostalAddress
      name:Kaiser Permanente
      address:
         name:Division of Research, Kaiser Permanente, Oakland, USA
         type:PostalAddress
      name:Kaiser Permanente
      address:
         name:Division of Research, Kaiser Permanente, Oakland, USA
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Marilyn L. Kwan
      affiliation:
            name:Kaiser Permanente
            address:
               name:Division of Research, Kaiser Permanente, Oakland, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Laurel A. Habel
      affiliation:
            name:Kaiser Permanente
            address:
               name:Division of Research, Kaiser Permanente, Oakland, USA
               type:PostalAddress
            type:Organization
      name:E. Dawn Flick
      affiliation:
            name:Kaiser Permanente
            address:
               name:Division of Research, Kaiser Permanente, Oakland, USA
               type:PostalAddress
            type:Organization
      name:Charles P. Quesenberry
      affiliation:
            name:Kaiser Permanente
            address:
               name:Division of Research, Kaiser Permanente, Oakland, USA
               type:PostalAddress
            type:Organization
      name:Bette Caan
      affiliation:
            name:Kaiser Permanente
            address:
               name:Division of Research, Kaiser Permanente, Oakland, USA
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Division of Research, Kaiser Permanente, Oakland, USA
      name:Division of Research, Kaiser Permanente, Oakland, USA
      name:Division of Research, Kaiser Permanente, Oakland, USA
      name:Division of Research, Kaiser Permanente, Oakland, USA
      name:Division of Research, Kaiser Permanente, Oakland, USA
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(96)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.21s.

LINK . SPRINGER . COM {}