We are analyzing https://link.springer.com/article/10.1007/s10549-005-0672-5.

Title:
Polymorphisms of the BRCA2 and RAD51 Genes in Breast Cancer | Breast Cancer Research and Treatment
Description:
We performed a case-control study (150 cases and 150 controls) to test the association between three polymorphisms in BRCA2 and RAD51 genes and breast cancer risk. Genotypes were determined in DNA from blood cells by PCR–RFLP. Cancer occurrence was strongly associated with the BRCA2 Met/1915Thr homozygous polymorphic variants, whereas heterozygous variant was associated with significant reduction in breast cancer risk. Gene-gene interaction between the BRCA2-Met1915Thr Thr/Thr and BRCA2-Met784Val Met/Met homozygous variants increased the risk. Therefore, the Met1915Thr polymorphism in the BRCA2 gene may be considered as an independent marker of breast cancer.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Health & Fitness
Education
Science

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We can't tell how the site generates income.

Websites don't always need to be profitable; some serve as platforms for education or personal expression. Websites can serve multiple purposes. And this might be one of them. Link.springer.com has a secret sauce for making money, but we can't detect it yet.

Keywords {🔍}

cancer, article, brca, breast, rad, pubmed, google, scholar, risk, dna, genes, polymorphism, gene, research, polymorphisms, lodz, privacy, cookies, content, access, repair, poland, publish, search, blasiak, association, carriers, analysis, data, information, log, journal, sliwinski, krupa, majsterek, rykala, kolacinska, morawiec, drzewoski, zadrozny, janusz, variants, discover, genetic, genetics, nature, download, author, springer, optional,

Topics {✒️}

month download article/chapter population-based studies conducted gene-gene interaction davies sc west breast cancer risk brca2-met1915thr thr/thr ireneusz majsterek & janusz blasiak case-control study related subjects brca1 carriers full article pdf privacy choices/manage cookies dna repair genes breast cancer brca1/2 variants molecular genetics genetic polymorphisms brca2 carriers brca2-rad51 complex single-nucleotide polymorphism single nucleotide polymorphism her2 gene polymorphisms rab163/mouse brca2 european economic area hamburger ra eeles albrecht ds lim copeland na jenkins lalande fw alt guanidine isothiocyanate acid enewold pg shields chorazy cc harris modan sm ebbers chetrit gh yechezkel author correspondence dna analysis poznan conditions privacy policy dna repair check access instant access article sliwinski accepting optional cookies radiation hypersensitivity mediated rad51 gene brca2 gene janusz blasiak cancer occurrence met/val article log journal finder publish clinical pharmacology

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Polymorphisms of the BRCA2 and RAD51 Genes in Breast Cancer
         description:We performed a case-control study (150 cases and 150 controls) to test the association between three polymorphisms in BRCA2 and RAD51 genes and breast cancer risk. Genotypes were determined in DNA from blood cells by PCR–RFLP. Cancer occurrence was strongly associated with the BRCA2 Met/1915Thr homozygous polymorphic variants, whereas heterozygous variant was associated with significant reduction in breast cancer risk. Gene-gene interaction between the BRCA2-Met1915Thr Thr/Thr and BRCA2-Met784Val Met/Met homozygous variants increased the risk. Therefore, the Met1915Thr polymorphism in the BRCA2 gene may be considered as an independent marker of breast cancer.
         datePublished:
         dateModified:
         pageStart:105
         pageEnd:109
         sameAs:https://doi.org/10.1007/s10549-005-0672-5
         keywords:
             BRCA2
            breast cancer
            DNA repair
            gene polymorphism
             RAD51
            Oncology
         image:
         isPartOf:
            name:Breast Cancer Research and Treatment
            issn:
               1573-7217
               0167-6806
            volumeNumber:94
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Kluwer Academic Publishers
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Tomasz Sliwinski
               affiliation:
                     name:University of Lodz
                     address:
                        name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Renata Krupa
               affiliation:
                     name:University of Lodz
                     address:
                        name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Ireneusz Majsterek
               affiliation:
                     name:University of Lodz
                     address:
                        name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jan Rykala
               affiliation:
                     name:N. Copernicus Hospital
                     address:
                        name:N. Copernicus Hospital, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Agnieszka Kolacinska
               affiliation:
                     name:N. Copernicus Hospital
                     address:
                        name:N. Copernicus Hospital, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Zbigniew Morawiec
               affiliation:
                     name:N. Copernicus Hospital
                     address:
                        name:N. Copernicus Hospital, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jozef Drzewoski
               affiliation:
                     name:Medical University of Lodz
                     address:
                        name:Department of Clinical Pharmacology, Medical University of Lodz, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Marek Zadrozny
               affiliation:
                     name:Polish Mother’s Memorial Hospital
                     address:
                        name:Polish Mother’s Memorial Hospital, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Janusz Blasiak
               affiliation:
                     name:University of Lodz
                     address:
                        name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Polymorphisms of the BRCA2 and RAD51 Genes in Breast Cancer
      description:We performed a case-control study (150 cases and 150 controls) to test the association between three polymorphisms in BRCA2 and RAD51 genes and breast cancer risk. Genotypes were determined in DNA from blood cells by PCR–RFLP. Cancer occurrence was strongly associated with the BRCA2 Met/1915Thr homozygous polymorphic variants, whereas heterozygous variant was associated with significant reduction in breast cancer risk. Gene-gene interaction between the BRCA2-Met1915Thr Thr/Thr and BRCA2-Met784Val Met/Met homozygous variants increased the risk. Therefore, the Met1915Thr polymorphism in the BRCA2 gene may be considered as an independent marker of breast cancer.
      datePublished:
      dateModified:
      pageStart:105
      pageEnd:109
      sameAs:https://doi.org/10.1007/s10549-005-0672-5
      keywords:
          BRCA2
         breast cancer
         DNA repair
         gene polymorphism
          RAD51
         Oncology
      image:
      isPartOf:
         name:Breast Cancer Research and Treatment
         issn:
            1573-7217
            0167-6806
         volumeNumber:94
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Kluwer Academic Publishers
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Tomasz Sliwinski
            affiliation:
                  name:University of Lodz
                  address:
                     name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Renata Krupa
            affiliation:
                  name:University of Lodz
                  address:
                     name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Ireneusz Majsterek
            affiliation:
                  name:University of Lodz
                  address:
                     name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jan Rykala
            affiliation:
                  name:N. Copernicus Hospital
                  address:
                     name:N. Copernicus Hospital, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Agnieszka Kolacinska
            affiliation:
                  name:N. Copernicus Hospital
                  address:
                     name:N. Copernicus Hospital, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Zbigniew Morawiec
            affiliation:
                  name:N. Copernicus Hospital
                  address:
                     name:N. Copernicus Hospital, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jozef Drzewoski
            affiliation:
                  name:Medical University of Lodz
                  address:
                     name:Department of Clinical Pharmacology, Medical University of Lodz, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Marek Zadrozny
            affiliation:
                  name:Polish Mother’s Memorial Hospital
                  address:
                     name:Polish Mother’s Memorial Hospital, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Janusz Blasiak
            affiliation:
                  name:University of Lodz
                  address:
                     name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Breast Cancer Research and Treatment
      issn:
         1573-7217
         0167-6806
      volumeNumber:94
Organization:
      name:Kluwer Academic Publishers
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Lodz
      address:
         name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
         type:PostalAddress
      name:University of Lodz
      address:
         name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
         type:PostalAddress
      name:University of Lodz
      address:
         name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
         type:PostalAddress
      name:N. Copernicus Hospital
      address:
         name:N. Copernicus Hospital, Lodz, Poland
         type:PostalAddress
      name:N. Copernicus Hospital
      address:
         name:N. Copernicus Hospital, Lodz, Poland
         type:PostalAddress
      name:N. Copernicus Hospital
      address:
         name:N. Copernicus Hospital, Lodz, Poland
         type:PostalAddress
      name:Medical University of Lodz
      address:
         name:Department of Clinical Pharmacology, Medical University of Lodz, Lodz, Poland
         type:PostalAddress
      name:Polish Mother’s Memorial Hospital
      address:
         name:Polish Mother’s Memorial Hospital, Lodz, Poland
         type:PostalAddress
      name:University of Lodz
      address:
         name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Tomasz Sliwinski
      affiliation:
            name:University of Lodz
            address:
               name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Renata Krupa
      affiliation:
            name:University of Lodz
            address:
               name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Ireneusz Majsterek
      affiliation:
            name:University of Lodz
            address:
               name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Jan Rykala
      affiliation:
            name:N. Copernicus Hospital
            address:
               name:N. Copernicus Hospital, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Agnieszka Kolacinska
      affiliation:
            name:N. Copernicus Hospital
            address:
               name:N. Copernicus Hospital, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Zbigniew Morawiec
      affiliation:
            name:N. Copernicus Hospital
            address:
               name:N. Copernicus Hospital, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Jozef Drzewoski
      affiliation:
            name:Medical University of Lodz
            address:
               name:Department of Clinical Pharmacology, Medical University of Lodz, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Marek Zadrozny
      affiliation:
            name:Polish Mother’s Memorial Hospital
            address:
               name:Polish Mother’s Memorial Hospital, Lodz, Poland
               type:PostalAddress
            type:Organization
      name:Janusz Blasiak
      affiliation:
            name:University of Lodz
            address:
               name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
      name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
      name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
      name:N. Copernicus Hospital, Lodz, Poland
      name:N. Copernicus Hospital, Lodz, Poland
      name:N. Copernicus Hospital, Lodz, Poland
      name:Department of Clinical Pharmacology, Medical University of Lodz, Lodz, Poland
      name:Polish Mother’s Memorial Hospital, Lodz, Poland
      name:Department of Molecular Genetics, University of Lodz, Lodz, Poland
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(80)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.56s.

LINK . SPRINGER . COM {}