We are analyzing https://link.springer.com/chapter/10.1007/s10254-002-0004-7.

Title:
Molecular basis of skeletal muscle plasticity-from gene to form and function | SpringerLink
Description:
Skeletal muscle shows an enormous plasticity to adapt to stimuli such as contractile activity (endurance exercise, electrical stimulation, denervation), loading conditions (resistance training, microgravity), substrate supply (nutritional interventions) or...
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Keywords {🔍}

google, scholar, pubmed, cas, article, muscle, physiol, skeletal, exercise, appl, human, protein, training, expression, gene, sci, factor, effects, kinase, central, med, biol, myosin, hoppeler, growth, mitochondrial, activity, endurance, chain, resistance, adaptations, hypoxia, cell, heavy, rat, acta, activation, response, scand, effect, endocrinol, regulation, genes, res, metab, humans, contractile, fiber, hormone, single,

Topics {✒️}

hypoxia-inducible factor hif-1alpha/arnt 3-day high-fat/low-carbohydrate diet peroxisome proliferator-activated receptors amp-activated protein kinase mitogen-activated protein kinase 5′-amp-activated protein kinase c-jun transcriptional activity alternative nf-kappab pathway stress-activated protein kinase peroxisomal enoyl-coa hydratase month download article/chapter hypoxia-inducible factor 1alpha hypoxia inducible factor-1alpha operation everest-ii-structural adaptations bcl-2/bax protein expression hypoxia/reoxygenation activate p65pak bicycle short-sprint training long-term hypobaric hypoxia terminal kinase activity training high-living low nuclear-encoded respiratory genes dupont-versteegden ee metal ion-catalyzed oxidation nuclear-encoded transcription factors extra-cellular lactate shuttles growth hormone-induced alterations short-term resistance training short-term strength training oxygen-dependent gene expression spinal cord-injured men short-term exercise training hypoxia-induced gene transcription myosin heavy chain high-intensity resistance training nonhypoxic pathway mediates thermogenic coactivator pgc-1 calcineurin-dependent pathway acetyl-coa carboxylase cultured endothelial cells amp kinase results mechanically induced signaling yarasheski ke heat-shock-protein cam kinase ii nuclear factor kappa fat rich diet acute exercise-induced increase exercise intensity-dependent activation hypoxia-inducible factor 1 hypoxia-inducible factor

Questions {❓}

Hudlicka O (1998) Is physiological angiogenesis in skeletal muscle regulated by changes in microcirculation?
Lindstedt SL, Wells DJ (1988) Skeletal muscle mitochondria: the aerobic gate?
Olson EN (1990) MyoD family: a paradigm for development?
Terrados N, Jansson E, Sylven C, Kaijser L (1990) Is hypoxia a stimulus for synthesis of oxidative enzymes and myoglobin?

Schema {🗺️}

ScholarlyArticle:
      headline:Molecular basis of skeletal muscle plasticity-from gene to form and function
      pageEnd:216
      pageStart:159
      image:https://media.springernature.com/w153/springer-static/cover/book/978-3-540-36207-4.jpg
      genre:
         Biomedical and Life Sciences
         Biomedical and Life Sciences (R0)
      isPartOf:
         name:Reviews of Physiology, Biochemistry and Pharmacology
         isbn:
            978-3-540-36207-4
            978-3-540-00228-4
         type:Book
      publisher:
         name:Springer Berlin Heidelberg
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:M. Flück
            affiliation:
                  name:University of Bern
                  address:
                     name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:H. Hoppeler
            affiliation:
                  name:University of Bern
                  address:
                     name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
                     type:PostalAddress
                  type:Organization
            type:Person
      keywords:Skeletal Muscle, Resistance Training, Satellite Cell, Caloric Restriction, Resistance Exercise
      description:Skeletal muscle shows an enormous plasticity to adapt to stimuli such as contractile activity (endurance exercise, electrical stimulation, denervation), loading conditions (resistance training, microgravity), substrate supply (nutritional interventions) or environmental factors (hypoxia). The presented data show that adaptive structural events occur in both muscle fibres (myofibrils, mitochondria) and associated structures (motoneurons and capillaries). Functional adaptations appear to involve alterations in regulatory mechanisms (neuronal, endocrine and intracellular signalling), contractile properties and metabolic capacities. With the appropriate molecular techniques it has been demonstrated over the past 10 years that rapid changes in skeletal muscle mRNA expression occur with exercise in human and rodent species. Recently, gene expression profiling analysis has demonstrated that transcriptional adaptations in skeletal muscle due to changes in loading involve a broad range of genes and that mRNA changes often run parallel for genes in the same functional categories. These changes can be matched to the structural/functional adaptations known to occur with corresponding stimuli. Several signalling pathways involving cytoplasmic protein kinases and nuclear-encoded transcription factors are recognized as potential master regulators that transduce physiological stress into transcriptional adaptations of batteries of metabolic and contractile genes. Nuclear reprogramming is recognized as an important event in muscle plasticity and may be related to the adaptations in the myosin type, protein turnover, and the cytoplasma-to-myonucleus ratio. The accessibility of muscle tissue to biopsies in conjunction with the advent of high-throughput gene expression analysis technology points to skeletal muscle plasticity as a particularly useful paradigm for studying gene regulatory phenomena in humans.
      datePublished:2003
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Book:
      name:Reviews of Physiology, Biochemistry and Pharmacology
      isbn:
         978-3-540-36207-4
         978-3-540-00228-4
Organization:
      name:Springer Berlin Heidelberg
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         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Bern
      address:
         name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
         type:PostalAddress
      name:University of Bern
      address:
         name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
         type:PostalAddress
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      name:M. Flück
      affiliation:
            name:University of Bern
            address:
               name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:H. Hoppeler
      affiliation:
            name:University of Bern
            address:
               name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
      name:Institute of Anatomy, University of Bern, Bern 9, Switzerland
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