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Title:
A multicenter study of patients with adult-onset Still’s disease compared with systemic juvenile idiopathic arthritis | Clinical Rheumatology
Description:
Adult-onset Still’s disease (AOSD) has often been regarded as the adult spectrum of systemic juvenile idiopathic arthritis (sJIA). The present study aims to compare the clinical and laboratory features, the disease course and the response to treatment in patients having AOSD with those having sJIA. Retrospective review of all available data that were filled out by adult and paediatric rheumatologists from six centers using a standard data extraction form was performed. A total of 95 patients with AOSD and 25 patients with sJIA were recruited for the study. The frequency of fever, rash, myalgia, weight loss and sore throat was higher in patients with AOSD. The pattern of joint involvement differed slightly. Laboratory findings were similar in both groups, except that liver dysfunction and neutrophilia were more common among adults. A multiphasic pattern dominated the childhood cases, whereas the most frequent course was a chronic one in adults. Corticosteroids and methotrexate were the most commonly employed therapy; however, chloroquine was another popular therapy in the adult group. We showed a difference in the rate of clinical and laboratory features between patients with AOSD and those with sJIA. AOSD and sJIA may still be the same disease, and children may simply be reacting differently as the result of the first encounter of the putative antigens with the immune system.
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disease, article, stills, pubmed, google, scholar, arthritis, cas, juvenile, patients, adultonset, idiopathic, ankara, adult, rheumatol, rheumatology, study, clin, systemic, aosd, onset, rheum, turkey, treatment, access, medicine, privacy, cookies, content, data, clinical, pay, sjia, school, publish, research, search, group, salih, adults, children, comparison, division, university, information, log, journal, multicenter, türkçapar, besbas,
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month download article/chapter juvenile idiopathic arthritis steroidal anti-inflammatory drugs full article pdf juvenile chronic arthritis privacy choices/manage cookies present study aims paediatric rheumatologists i̇hsan ertenli inflammatory orbital pseudotumor i̇smail şimşek european economic area akif öztürk olcay tiryaki aydıntuğ mustafa turan long term evolution acute-phase proteins gulhane military school hacettepe university school gazi university school multicenter study ankara university school ankara numune training conditions privacy policy commonly employed therapy check access instant access accepting optional cookies multiphasic pattern dominated related subjects long-term outcome adult group article log interleukin-18 gene polymorphisms main content log juvenile onset murat turgay proposed classification criteria arthritis rheum 44 arthritis rheum 46 arthritis rheum 48 journal finder publish author correspondence research hospital article cite hakan erdem sedat kiraz ayhan dinç aşkın ateş meral çalgüneri
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headline:A multicenter study of patients with adult-onset Still’s disease compared with systemic juvenile idiopathic arthritis
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name:Division of Rheumatology, Gulhane Military School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Aşkın Ateş
affiliation:
name:Ankara Numune Training and Research Hospital
address:
name:Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey
type:PostalAddress
type:Organization
name:Ümit Ölmez
affiliation:
name:Ankara University School of Medicine
address:
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Meral Çalgüneri
affiliation:
name:Hacettepe University School of Medicine
address:
name:Division of Rheumatology, Hacettepe University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Olcay Tiryaki Aydıntuğ
affiliation:
name:Ankara University School of Medicine
address:
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Ayşin Bakkaloğlu
affiliation:
name:Hacettepe University School of Medicine
address:
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Mustafa Turan
affiliation:
name:Gazi University School of Medicine
address:
name:Division of Rheumatology, Gazi University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Murat Turgay
affiliation:
name:Ankara University School of Medicine
address:
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Yaşar Karaaslan
affiliation:
name:Ankara Numune Training and Research Hospital
address:
name:Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey
type:PostalAddress
type:Organization
name:Rezzan Topaloğlu
affiliation:
name:Hacettepe University School of Medicine
address:
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Murat Duman
affiliation:
name:Ankara University School of Medicine
address:
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
name:Seza Özen
affiliation:
name:Hacettepe University School of Medicine
address:
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
type:PostalAddress
type:Organization
PostalAddress:
name:Division of Rheumatology, Gulhane Military School of Medicine, Ankara, Turkey
name:GATA Romatoloji BD, Ankara, Turkey
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
name:Division of Rheumatology, Gulhane Military School of Medicine, Ankara, Turkey
name:Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey
name:Division of Rheumatology, Hacettepe University School of Medicine, Ankara, Turkey
name:Division of Rheumatology, Gazi University School of Medicine, Ankara, Turkey
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
name:Division of Rheumatology, Gulhane Military School of Medicine, Ankara, Turkey
name:Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey
name:Division of Rheumatology, Hacettepe University School of Medicine, Ankara, Turkey
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
name:Division of Rheumatology, Gulhane Military School of Medicine, Ankara, Turkey
name:Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
name:Division of Rheumatology, Hacettepe University School of Medicine, Ankara, Turkey
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
name:Division of Rheumatology, Gazi University School of Medicine, Ankara, Turkey
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
name:Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
name:Division of Immunology and Rheumatology, Ankara University School of Medicine, Ankara, Turkey
name:Department of Pediatrics, Hacettepe University School of Medicine, Ankara, Turkey
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