We began analyzing https://www.nature.com/articles/jhg2006100, but it redirected us to https://www.nature.com/articles/jhg2006100. The analysis below is for the second page.

Title[redir]:
The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage | Journal of Human Genetics
Description:
The tumor suppressor p53 plays a crucial role in the cellular response to DNA damage by transcriptional activation of numerous downstream genes. Although a considerable number of p53 target genes have been reported, the precise mechanism of p53-regulated tumor suppression still remains to be elucidated. Here, we report a novel role of the DFNA5 gene in p53-mediated etoposide-induced cell death. The DFNA5 gene has been previously reported to be responsible for autosomal-dominant, nonsyndromic hearing impairment. The expression of the DFNA5 gene was strongly induced by exogenous and endogenous p53. The chromatin immunoprecipitation assay indicated that a potential p53-binding sequence is located in intron 1 of the DFNA5 gene. Furthermore, the reporter gene assay revealed that the sequence displays p53-dependent transcriptional activity. The ectopic expression of DFNA5 enhanced etoposide-induced cell death in the presence of p53; however, it was inhibited in the absence of p53. Finally, the expression of DFNA5 mRNA was remarkably induced by gamma-ray irradiation in the colon of p53(+/+) mice but not in that of p53(−/−) mice. These results suggest that DFNA5 plays a role in the p53-regulated cellular response to genotoxic stress probably by cooperating with p53.

Matching Content Categories {📚}

Science
Education
Telecommunications

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We're unsure if the website is profiting.

While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Link.springer.com might be earning cash quietly, but we haven't detected the monetization method.

Keywords {🔍}

dfna, cells, expression, cell, gene, dna, article, google, scholar, cas, fig, response, pbs, cancer, protein, role, damage, apoptosis, analysis, mrna, nature, cellular, mice, hearing, function, human, impairment, death, assay, pdependent, antibody, nakamura, arakawa, etoposideinduced, hepg, wildtype, genes, pregulated, line, apoptotic, target, pwaf, infected, van, mutant, sequences, reported, sequence, presence, results,

Topics {✒️}

nature portfolio si-mscv-puro-h1r-p53ri retrovirus permissions reprints privacy policy si-mscv-puro-h1r retrovirus open reading frame mrna purification kits advertising include cell-cycle-regulating proteins nature 404 nature 408 nature p53-dependent cell-cycle checkpoint pcr-blunt ii-topo plasmid etoposide-resistant mewo-eto-1 cells social media pcr-blunt ii-topo etoposide-induced cell death author information authors p53-inducible ubiquitin-protein ligase genotoxin-induced cell death parental mewo-eto-1 cells semi-quantitative rt-pcr analysis tumor suppressor p53 etoposide-induced dna damage dna damage-induced apoptosis author correspondence predictive p53 binding-sites brain-specific p53-target gene p53-regulated tumor suppression dna damage-repair proteins hiroshi egami & hideo baba induce p53-dependent apoptosis induce p53-dependent apotosis ecori-digested dna fragment hepg2-p53-cont cells subjected lung-cancer cell line consensus p53-binding sequence regulates p53-dependent apoptosis gsdme-mediated pyroptosis promotes semi-quantitative rt-pcr 4 mg/ml bromophenol blue gamma-irradiation-induced apoptosis mouse anti-flag antibody etoposide-induced apoptotic cells p53-dependent apoptotic pathway g418-resistant colonies grown p53-independent ceramide formation pyroptosis cell death p53-mediated cellular response

Questions {❓}

Furthermore, does DFNA5 mediate the p53-regulated cellular response outside the cochlea?
How do we explain such contrasting dual roles of DFNA5 in the cellular response to DNA damage?
The most important question is how and where does DFNA5 function as a mediator of p53?
Van Laer L, Vrijiens K, Thys S et al (2004) DFNA5: hearing impairment exon instead of hearing impairment gene?

Schema {🗺️}

WebPage:
      mainEntity:
         headline:The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage
         description:The tumor suppressor p53 plays a crucial role in the cellular response to DNA damage by transcriptional activation of numerous downstream genes. Although a considerable number of p53 target genes have been reported, the precise mechanism of p53-regulated tumor suppression still remains to be elucidated. Here, we report a novel role of the DFNA5 gene in p53-mediated etoposide-induced cell death. The DFNA5 gene has been previously reported to be responsible for autosomal-dominant, nonsyndromic hearing impairment. The expression of the DFNA5 gene was strongly induced by exogenous and endogenous p53. The chromatin immunoprecipitation assay indicated that a potential p53-binding sequence is located in intron 1 of the DFNA5 gene. Furthermore, the reporter gene assay revealed that the sequence displays p53-dependent transcriptional activity. The ectopic expression of DFNA5 enhanced etoposide-induced cell death in the presence of p53; however, it was inhibited in the absence of p53. Finally, the expression of DFNA5 mRNA was remarkably induced by gamma-ray irradiation in the colon of p53(+/+) mice but not in that of p53(â/â) mice. These results suggest that DFNA5 plays a role in the p53-regulated cellular response to genotoxic stress probably by cooperating with p53.
         datePublished:2006-08-01T00:00:00Z
         dateModified:2006-08-01T00:00:00Z
         pageStart:652
         pageEnd:664
         sameAs:https://doi.org/10.1007/s10038-006-0004-6
         keywords:
            p53
            Tumor suppressor gene
            Hearing impairment
            DNA damage
            Cell death
            Apoptosis
            Etoposide
            p53 target gene
            Human Genetics
            Molecular Medicine
            Gene Function
            Gene Expression
            Gene Therapy
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig5_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig6_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig7_HTML.gif
         isPartOf:
            name:Journal of Human Genetics
            issn:
               1435-232X
               1434-5161
            volumeNumber:51
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer Japan
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:Yoshiko Masuda
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
                     name:Kumamoto University
                     address:
                        name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Manabu Futamura
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hiroki Kamino
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Yasuyuki Nakamura
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Noriaki Kitamura
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Shiho Ohnishi
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Yuji Miyamoto
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hitoshi Ichikawa
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Transcriptome Project, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tsutomu Ohta
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Misao Ohki
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Tohru Kiyono
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Virology Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hiroshi Egami
               affiliation:
                     name:Kumamoto University
                     address:
                        name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hideo Baba
               affiliation:
                     name:Kumamoto University
                     address:
                        name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Hirofumi Arakawa
               affiliation:
                     name:National Cancer Center Research Institute
                     address:
                        name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
         isAccessibleForFree:1
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage
      description:The tumor suppressor p53 plays a crucial role in the cellular response to DNA damage by transcriptional activation of numerous downstream genes. Although a considerable number of p53 target genes have been reported, the precise mechanism of p53-regulated tumor suppression still remains to be elucidated. Here, we report a novel role of the DFNA5 gene in p53-mediated etoposide-induced cell death. The DFNA5 gene has been previously reported to be responsible for autosomal-dominant, nonsyndromic hearing impairment. The expression of the DFNA5 gene was strongly induced by exogenous and endogenous p53. The chromatin immunoprecipitation assay indicated that a potential p53-binding sequence is located in intron 1 of the DFNA5 gene. Furthermore, the reporter gene assay revealed that the sequence displays p53-dependent transcriptional activity. The ectopic expression of DFNA5 enhanced etoposide-induced cell death in the presence of p53; however, it was inhibited in the absence of p53. Finally, the expression of DFNA5 mRNA was remarkably induced by gamma-ray irradiation in the colon of p53(+/+) mice but not in that of p53(â/â) mice. These results suggest that DFNA5 plays a role in the p53-regulated cellular response to genotoxic stress probably by cooperating with p53.
      datePublished:2006-08-01T00:00:00Z
      dateModified:2006-08-01T00:00:00Z
      pageStart:652
      pageEnd:664
      sameAs:https://doi.org/10.1007/s10038-006-0004-6
      keywords:
         p53
         Tumor suppressor gene
         Hearing impairment
         DNA damage
         Cell death
         Apoptosis
         Etoposide
         p53 target gene
         Human Genetics
         Molecular Medicine
         Gene Function
         Gene Expression
         Gene Therapy
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig5_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig6_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs10038-006-0004-6/MediaObjects/10038_2006_4_Fig7_HTML.gif
      isPartOf:
         name:Journal of Human Genetics
         issn:
            1435-232X
            1434-5161
         volumeNumber:51
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer Japan
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:Yoshiko Masuda
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
                  name:Kumamoto University
                  address:
                     name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Manabu Futamura
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hiroki Kamino
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Yasuyuki Nakamura
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Noriaki Kitamura
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Shiho Ohnishi
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Yuji Miyamoto
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hitoshi Ichikawa
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Transcriptome Project, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tsutomu Ohta
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Misao Ohki
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Tohru Kiyono
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Virology Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hiroshi Egami
            affiliation:
                  name:Kumamoto University
                  address:
                     name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hideo Baba
            affiliation:
                  name:Kumamoto University
                  address:
                     name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Hirofumi Arakawa
            affiliation:
                  name:National Cancer Center Research Institute
                  address:
                     name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
      isAccessibleForFree:1
["Periodical","PublicationVolume"]:
      name:Journal of Human Genetics
      issn:
         1435-232X
         1434-5161
      volumeNumber:51
Organization:
      name:Springer Japan
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:Kumamoto University
      address:
         name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Transcriptome Project, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Virology Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
      name:Kumamoto University
      address:
         name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
         type:PostalAddress
      name:Kumamoto University
      address:
         name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
         type:PostalAddress
      name:National Cancer Center Research Institute
      address:
         name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:Yoshiko Masuda
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
            name:Kumamoto University
            address:
               name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
               type:PostalAddress
            type:Organization
      name:Manabu Futamura
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Hiroki Kamino
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Yasuyuki Nakamura
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Noriaki Kitamura
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Shiho Ohnishi
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Yuji Miyamoto
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Hitoshi Ichikawa
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Transcriptome Project, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Tsutomu Ohta
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Misao Ohki
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Tohru Kiyono
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Virology Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      name:Hiroshi Egami
      affiliation:
            name:Kumamoto University
            address:
               name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
               type:PostalAddress
            type:Organization
      name:Hideo Baba
      affiliation:
            name:Kumamoto University
            address:
               name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
               type:PostalAddress
            type:Organization
      name:Hirofumi Arakawa
      affiliation:
            name:National Cancer Center Research Institute
            address:
               name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
               type:PostalAddress
            type:Organization
      email:[email protected]
PostalAddress:
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Cancer Transcriptome Project, National Cancer Center Research Institute, Tokyo, Japan
      name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
      name:Center for Medical Genomics, National Cancer Center Research Institute, Tokyo, Japan
      name:Virology Division, National Cancer Center Research Institute, Tokyo, Japan
      name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
      name:Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan
      name:Cancer Medicine and Biophysics Division, National Cancer Center Research Institute, Tokyo, Japan

External Links {🔗}(310)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Prism.js
Zoom.js

CDN Services {📦}

Crossref

4.57s.

LINK . SPRINGER . COM {}