We are analyzing https://link.springer.com/article/10.1007/s00894-005-0047-1.

Title:
Bioactive principles in the bark of Pilidiostigma tropicum | Journal of Molecular Modeling
Description:
The crude dichloromethane bark extract of Pilidiostigma tropicum (Myrtaceae) from north Queensland, Australia, shows antibacterial and cytotoxic activity. Bioactivity-directed separation led to the isolation of rhodomyrtoxin B and ursolic acid-3-p-coumarate as the biologically active materials. The structures of these compounds were elucidated on the basis of spectral analysis. The intercalation interaction of rhodomyrtoxin B with DNA was investigated using molecular mechanics and ab initio molecular-orbital techniques. A favorable π−π interaction between rhodomyrtoxin B and the cytosine–guanine base pair is predicted, but the orientation of the interaction cannot be predicted based on frontier molecular orbitals.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Education
Science
Virtual Reality

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 7,643,078 visitors per month in the current month.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

We find it hard to spot revenue streams.

Earning money isn't the goal of every website; some are designed to offer support or promote social causes. People have different reasons for creating websites. This might be one such reason. Link.springer.com could be getting rich in stealth mode, or the way it's monetizing isn't detectable.

Keywords {🔍}

google, scholar, article, cas, pubmed, chem, setzer, med, mol, access, phys, australia, rev, privacy, cookies, content, journal, research, molecular, queensland, rhodomyrtoxin, biochemistry, information, publish, search, bark, pilidiostigma, tropicum, jackes, biol, tropical, forest, phytochemistry, nomizu, nishi, chen, soc, sponer, hobza, data, log, william, rozmus, antibacterial, interaction, open, september, discover, chemistry, melbourne,

Topics {✒️}

ursolic acid-3-p-coumarate month download article/chapter cytosine–guanine base pair bioactivity-directed separation led favorable π−π interaction de silva kmn full article pdf van boom jh privacy choices/manage cookies molecular modeling aims frontier molecular orbitals vitro antibacterial effects australian medicinal plants humid tropical region european economic area biologically active materials dissolved organic matter related subjects comp biochem physiol lee kh dos santos mc queensland forest service conditions privacy policy article journal le pecq jb article setzer accepting optional cookies bernhard vogler pilidiostigma tropicum author information authors james cook university setzer wn journal finder publish article log main content log predicted based article cite bioactive principles check access instant access rowan mg bible rh voet jg cytotoxicity screening denny wa sabine reeb shows antibacterial molecular mechanics bender bc kaufmann sh

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Bioactive principles in the bark of Pilidiostigma tropicum
         description:The crude dichloromethane bark extract of Pilidiostigma tropicum (Myrtaceae) from north Queensland, Australia, shows antibacterial and cytotoxic activity. Bioactivity-directed separation led to the isolation of rhodomyrtoxin B and ursolic acid-3-p-coumarate as the biologically active materials. The structures of these compounds were elucidated on the basis of spectral analysis. The intercalation interaction of rhodomyrtoxin B with DNA was investigated using molecular mechanics and ab initio molecular-orbital techniques. A favorable π−π interaction between rhodomyrtoxin B and the cytosine–guanine base pair is predicted, but the orientation of the interaction cannot be predicted based on frontier molecular orbitals.
         datePublished:2006-04-07T00:00:00Z
         dateModified:2006-04-07T00:00:00Z
         pageStart:703
         pageEnd:711
         sameAs:https://doi.org/10.1007/s00894-005-0047-1
         keywords:
            Cytotoxicity
            Antibacterial
             Pilidiostigma tropicum
            Rhodomyrtoxin B
            Ursolic acid coumarate
            Intercalation
            Computer Applications in Chemistry
            Molecular Medicine
            Computer Appl. in Life Sciences
            Characterization and Evaluation of Materials
            Theoretical and Computational Chemistry
         image:
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Figa_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Sch1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig1_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig2_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig3_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig4_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig5_HTML.jpg
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig6_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig7_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig8_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig9_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig10_HTML.gif
            https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig11_HTML.gif
         isPartOf:
            name:Journal of Molecular Modeling
            issn:
               0948-5023
               1610-2940
            volumeNumber:12
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:William N. Setzer
               affiliation:
                     name:University of Alabama in Huntsville
                     address:
                        name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                        type:PostalAddress
                     type:Organization
               email:[email protected]
               type:Person
               name:Glenn F. Rozmus
               affiliation:
                     name:University of Alabama in Huntsville
                     address:
                        name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Mary C. Setzer
               affiliation:
                     name:University of Alabama in Huntsville
                     address:
                        name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Jennifer M. Schmidt
               affiliation:
                     name:University of Alabama in Huntsville
                     address:
                        name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Bernhard Vogler
               affiliation:
                     name:University of Alabama in Huntsville
                     address:
                        name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Sabine Reeb
               affiliation:
                     name:Universität Hohenheim
                     address:
                        name:Institut für Chemie, Universität Hohenheim, Stuttgart, Germany
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Betsy R. Jackes
               affiliation:
                     name:James Cook University
                     address:
                        name:School of Tropical Biology, James Cook University, Townsville, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
               name:Anthony K. Irvine
               affiliation:
                     name:Tropical Forest Research Centre
                     address:
                        name:C. S. I. R. O., Tropical Forest Research Centre, Atherton, Australia
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Bioactive principles in the bark of Pilidiostigma tropicum
      description:The crude dichloromethane bark extract of Pilidiostigma tropicum (Myrtaceae) from north Queensland, Australia, shows antibacterial and cytotoxic activity. Bioactivity-directed separation led to the isolation of rhodomyrtoxin B and ursolic acid-3-p-coumarate as the biologically active materials. The structures of these compounds were elucidated on the basis of spectral analysis. The intercalation interaction of rhodomyrtoxin B with DNA was investigated using molecular mechanics and ab initio molecular-orbital techniques. A favorable π−π interaction between rhodomyrtoxin B and the cytosine–guanine base pair is predicted, but the orientation of the interaction cannot be predicted based on frontier molecular orbitals.
      datePublished:2006-04-07T00:00:00Z
      dateModified:2006-04-07T00:00:00Z
      pageStart:703
      pageEnd:711
      sameAs:https://doi.org/10.1007/s00894-005-0047-1
      keywords:
         Cytotoxicity
         Antibacterial
          Pilidiostigma tropicum
         Rhodomyrtoxin B
         Ursolic acid coumarate
         Intercalation
         Computer Applications in Chemistry
         Molecular Medicine
         Computer Appl. in Life Sciences
         Characterization and Evaluation of Materials
         Theoretical and Computational Chemistry
      image:
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Figa_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Sch1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig1_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig2_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig3_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig4_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig5_HTML.jpg
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig6_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig7_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig8_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig9_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig10_HTML.gif
         https://media.springernature.com/lw1200/springer-static/image/art%3A10.1007%2Fs00894-005-0047-1/MediaObjects/894_2005_47_Fig11_HTML.gif
      isPartOf:
         name:Journal of Molecular Modeling
         issn:
            0948-5023
            1610-2940
         volumeNumber:12
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:William N. Setzer
            affiliation:
                  name:University of Alabama in Huntsville
                  address:
                     name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                     type:PostalAddress
                  type:Organization
            email:[email protected]
            type:Person
            name:Glenn F. Rozmus
            affiliation:
                  name:University of Alabama in Huntsville
                  address:
                     name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Mary C. Setzer
            affiliation:
                  name:University of Alabama in Huntsville
                  address:
                     name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Jennifer M. Schmidt
            affiliation:
                  name:University of Alabama in Huntsville
                  address:
                     name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Bernhard Vogler
            affiliation:
                  name:University of Alabama in Huntsville
                  address:
                     name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Sabine Reeb
            affiliation:
                  name:Universität Hohenheim
                  address:
                     name:Institut für Chemie, Universität Hohenheim, Stuttgart, Germany
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Betsy R. Jackes
            affiliation:
                  name:James Cook University
                  address:
                     name:School of Tropical Biology, James Cook University, Townsville, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
            name:Anthony K. Irvine
            affiliation:
                  name:Tropical Forest Research Centre
                  address:
                     name:C. S. I. R. O., Tropical Forest Research Centre, Atherton, Australia
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Journal of Molecular Modeling
      issn:
         0948-5023
         1610-2940
      volumeNumber:12
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:University of Alabama in Huntsville
      address:
         name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
         type:PostalAddress
      name:University of Alabama in Huntsville
      address:
         name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
         type:PostalAddress
      name:University of Alabama in Huntsville
      address:
         name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
         type:PostalAddress
      name:University of Alabama in Huntsville
      address:
         name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
         type:PostalAddress
      name:University of Alabama in Huntsville
      address:
         name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
         type:PostalAddress
      name:Universität Hohenheim
      address:
         name:Institut für Chemie, Universität Hohenheim, Stuttgart, Germany
         type:PostalAddress
      name:James Cook University
      address:
         name:School of Tropical Biology, James Cook University, Townsville, Australia
         type:PostalAddress
      name:Tropical Forest Research Centre
      address:
         name:C. S. I. R. O., Tropical Forest Research Centre, Atherton, Australia
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:William N. Setzer
      affiliation:
            name:University of Alabama in Huntsville
            address:
               name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
               type:PostalAddress
            type:Organization
      email:[email protected]
      name:Glenn F. Rozmus
      affiliation:
            name:University of Alabama in Huntsville
            address:
               name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
               type:PostalAddress
            type:Organization
      name:Mary C. Setzer
      affiliation:
            name:University of Alabama in Huntsville
            address:
               name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
               type:PostalAddress
            type:Organization
      name:Jennifer M. Schmidt
      affiliation:
            name:University of Alabama in Huntsville
            address:
               name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
               type:PostalAddress
            type:Organization
      name:Bernhard Vogler
      affiliation:
            name:University of Alabama in Huntsville
            address:
               name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
               type:PostalAddress
            type:Organization
      name:Sabine Reeb
      affiliation:
            name:Universität Hohenheim
            address:
               name:Institut für Chemie, Universität Hohenheim, Stuttgart, Germany
               type:PostalAddress
            type:Organization
      name:Betsy R. Jackes
      affiliation:
            name:James Cook University
            address:
               name:School of Tropical Biology, James Cook University, Townsville, Australia
               type:PostalAddress
            type:Organization
      name:Anthony K. Irvine
      affiliation:
            name:Tropical Forest Research Centre
            address:
               name:C. S. I. R. O., Tropical Forest Research Centre, Atherton, Australia
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
      name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
      name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
      name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
      name:Department of Chemistry, University of Alabama in Huntsville, Huntsville, USA
      name:Institut für Chemie, Universität Hohenheim, Stuttgart, Germany
      name:School of Tropical Biology, James Cook University, Townsville, Australia
      name:C. S. I. R. O., Tropical Forest Research Centre, Atherton, Australia
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(207)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.27s.

LINK . SPRINGER . COM {}