We are analyzing https://link.springer.com/article/10.1007/s007050170114.

Title:
Characterization of a new adenovirus isolated from black-tailed deer in California | Archives of Virology
Description:
An adenovirus associated with systemic and localized vascular damage was demonstrated by transmission electron microscopy and immunohistochemistry in a newly recognized epizootic hemorrhagic disease in California black-tailed deer. In this study, we describe the cultural, physicochemical and serological characteristics of a virus isolated from lung using neonatal white-tail deer lung and turbinate cell cultures. The virus had the cultural, morpholog-ical and physicochemical characteristics of members of the Adenoviridae family. The virus would not replicate in low passage fetal bovine, caprine or ovine cells. Antiserum to the deer adenovirus, strain D94-2569, neutralized bovine adenovirus type-6 (BAdV-6), BAdV-7, and caprine adenovirus type-1 (GAdV-1). Antiserum to BAdV-6 did not neutralize the deer adenovirus but antiserum to BAdV-7 and GAdV-1 neutralized the deer adenovirus. Cross-neutralization with the other bovine, caprine and ovine adeno-virus species was not observed. Restriction endonuclease patterns generated for the deer adenovirus were unique compared to those for the currently recognized bovine, caprine and ovine adeno-virus types. Amino acid sequence alignments of the hexon gene from the deer adenovirus strain D94-2569 indicate that it is a member of the proposed new genus (Atadenovirus) of the Adenoviridae family. While closely related antigenically to BAdV-7 and GAdV-1, the deer adenovirus appears sufficiently distinct culturally and molecularly to justify consideration as a new adenovirus type.
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Keywords {🔍}

adenovirus, article, deer, california, bovine, access, privacy, cookies, content, research, type, badv, information, publish, search, isolated, caprine, data, log, journal, characterization, blacktailed, lehmkuhl, hobbs, woods, physicochemical, virus, ovine, antiserum, strain, gadv, sequence, related, open, discover, usa, springer, optional, personal, parties, policy, find, track, archives, virology, cite, explore, vascular, damage, recognized,

Topics {✒️}

localized vascular damage month download article/chapter ovine adeno-virus species ovine adeno-virus types related subjects california black-tailed deer caprine adenovirus type-1 closely related antigenically privacy choices/manage cookies adenovirus type livestock research unit agricultural research service full article pdf black-tailed deer european economic area scope submit manuscript transmission electron microscopy turbinate cell cultures check access systemically infected calf united states department instant access conditions privacy policy accepting optional cookies physicochemical characteristics hexon gene main content log deer adenovirus journal finder publish article archives recognized bovine adenovirus isolated physicochemical virus isolated veterinary medicine article log privacy policy personal data strain d94-2569 books a ovine cells article cite optional cookies article lehmkuhl manage preferences information data protection strain isolated essential cookies cookies skip

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         headline:Characterization of a new adenovirus isolated from black-tailed deer in California
         description: An adenovirus associated with systemic and localized vascular damage was demonstrated by transmission electron microscopy and immunohistochemistry in a newly recognized epizootic hemorrhagic disease in California black-tailed deer. In this study, we describe the cultural, physicochemical and serological characteristics of a virus isolated from lung using neonatal white-tail deer lung and turbinate cell cultures. The virus had the cultural, morpholog-ical and physicochemical characteristics of members of the Adenoviridae family. The virus would not replicate in low passage fetal bovine, caprine or ovine cells. Antiserum to the deer adenovirus, strain D94-2569, neutralized bovine adenovirus type-6 (BAdV-6), BAdV-7, and caprine adenovirus type-1 (GAdV-1). Antiserum to BAdV-6 did not neutralize the deer adenovirus but antiserum to BAdV-7 and GAdV-1 neutralized the deer adenovirus. Cross-neutralization with the other bovine, caprine and ovine adeno-virus species was not observed. Restriction endonuclease patterns generated for the deer adenovirus were unique compared to those for the currently recognized bovine, caprine and ovine adeno-virus types. Amino acid sequence alignments of the hexon gene from the deer adenovirus strain D94-2569 indicate that it is a member of the proposed new genus (Atadenovirus) of the Adenoviridae family. While closely related antigenically to BAdV-7 and GAdV-1, the deer adenovirus appears sufficiently distinct culturally and molecularly to justify consideration as a new adenovirus type.
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            Adenovirus Type
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      headline:Characterization of a new adenovirus isolated from black-tailed deer in California
      description: An adenovirus associated with systemic and localized vascular damage was demonstrated by transmission electron microscopy and immunohistochemistry in a newly recognized epizootic hemorrhagic disease in California black-tailed deer. In this study, we describe the cultural, physicochemical and serological characteristics of a virus isolated from lung using neonatal white-tail deer lung and turbinate cell cultures. The virus had the cultural, morpholog-ical and physicochemical characteristics of members of the Adenoviridae family. The virus would not replicate in low passage fetal bovine, caprine or ovine cells. Antiserum to the deer adenovirus, strain D94-2569, neutralized bovine adenovirus type-6 (BAdV-6), BAdV-7, and caprine adenovirus type-1 (GAdV-1). Antiserum to BAdV-6 did not neutralize the deer adenovirus but antiserum to BAdV-7 and GAdV-1 neutralized the deer adenovirus. Cross-neutralization with the other bovine, caprine and ovine adeno-virus species was not observed. Restriction endonuclease patterns generated for the deer adenovirus were unique compared to those for the currently recognized bovine, caprine and ovine adeno-virus types. Amino acid sequence alignments of the hexon gene from the deer adenovirus strain D94-2569 indicate that it is a member of the proposed new genus (Atadenovirus) of the Adenoviridae family. While closely related antigenically to BAdV-7 and GAdV-1, the deer adenovirus appears sufficiently distinct culturally and molecularly to justify consideration as a new adenovirus type.
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      dateModified:
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         Sequence Alignment
         Physicochemical Characteristic
         Vascular Damage
         Amino Acid Sequence Alignment
         Adenovirus Type
         Virology
         Medical Microbiology
         Infectious Diseases
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