We are analyzing https://link.springer.com/article/10.1007/s004380050959.

Title:
Zinc finger proteins: watchdogs in muscle development | Molecular Genetics and Genomics
Description:
The specificity of highly differentiated tissues is largely achieved through the action of cell- and stage-restricted transcription factors. The basic events in skeletal muscle development are triggered by a unique family of myogenic basic helix-loop-helix proteins –MyoD, Myf-5, myogenin and MRF-4. Binding sites for these factors are found in the promoter regions of many genes whose expression is restricted to muscle cells, but the tight regulation of gene expression is dependent on the interaction of different factors. In this respect zinc finger proteins seem to play an important role, not only in the establishment of muscle cells but also in the maintenance of muscle function. This review discusses several zinc finger proteins that have been characterized as regulators of muscle development and muscle-specific gene expression.
Website Age:
28 years and 1 months (reg. 1997-05-29).

Matching Content Categories {📚}

Science
Fitness & Wellness
Education

Content Management System {📝}

What CMS is link.springer.com built with?

Custom-built

No common CMS systems were detected on Link.springer.com, and no known web development framework was identified.

Traffic Estimate {📈}

What is the average monthly size of link.springer.com audience?

🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 5,000,019 visitors per month in the current month.
However, some sources were not loaded, we suggest to reload the page to get complete results.

check SE Ranking
check Ahrefs
check Similarweb
check Ubersuggest
check Semrush

How Does Link.springer.com Make Money? {💸}

The income method remains a mystery to us.

Not all websites focus on profit; some are designed to educate, connect people, or share useful tools. People create websites for numerous reasons. And this could be one such example. Link.springer.com could have a money-making trick up its sleeve, but it's undetectable for now.

Keywords {🔍}

article, muscle, zinc, proteins, finger, access, privacy, cookies, content, development, information, publish, search, factors, skeletal, data, log, journal, research, krempler, brenig, basic, expression, regulation, open, discover, protein, springer, function, optional, personal, parties, policy, find, track, molecular, general, genetics, mgg, watchdogs, review, cite, explore, transcription, myod, mrf, cells, gene, regulators, institution,

Topics {✒️}

zinc finger proteins stage-restricted transcription factors month download article/chapter binding sites skeletal muscle development germany e-mail muscle-specific gene expression privacy choices/manage cookies full article pdf regulators tight regulation negative regulation muscle development european economic area scope submit manuscript highly differentiated tissues check access related subjects instant access conditions privacy policy accepting optional cookies article molecular main content log skeletal myogenesis journal finder publish mrf-4 muscle cells information factors article log muscle function basic events article cite privacy policy personal data article krempler books a gene expression optional cookies manage preferences review discusses data protection essential cookies cookies skip subscription content similar content institution subscribe journal publish usage analysis social media

Schema {🗺️}

WebPage:
      mainEntity:
         headline:Zinc finger proteins: watchdogs in muscle development
         description: The specificity of highly differentiated tissues is largely achieved through the action of cell- and stage-restricted transcription factors. The basic events in skeletal muscle development are triggered by a unique family of myogenic basic helix-loop-helix proteins –MyoD, Myf-5, myogenin and MRF-4. Binding sites for these factors are found in the promoter regions of many genes whose expression is restricted to muscle cells, but the tight regulation of gene expression is dependent on the interaction of different factors. In this respect zinc finger proteins seem to play an important role, not only in the establishment of muscle cells but also in the maintenance of muscle function. This review discusses several zinc finger proteins that have been characterized as regulators of muscle development and muscle-specific gene expression.
         datePublished:
         dateModified:
         pageStart:209
         pageEnd:215
         sameAs:https://doi.org/10.1007/s004380050959
         keywords:
            Key words Zinc finger protein
            Muscle development
            E-box
            MRF
            MyoD
            Plant Genetics and Genomics
            Human Genetics
            Microbial Genetics and Genomics
            Animal Genetics and Genomics
            Biochemistry
            general
         image:
         isPartOf:
            name:Molecular and General Genetics MGG
            issn:
               1432-1874
               0026-8925
            volumeNumber:261
            type:
               Periodical
               PublicationVolume
         publisher:
            name:Springer-Verlag
            logo:
               url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
               type:ImageObject
            type:Organization
         author:
               name:A. Krempler
               affiliation:
                     name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
                     address:
                        name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
               name:B. Brenig
               affiliation:
                     name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
                     address:
                        name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
                        type:PostalAddress
                     type:Organization
               type:Person
         isAccessibleForFree:
         hasPart:
            isAccessibleForFree:
            cssSelector:.main-content
            type:WebPageElement
         type:ScholarlyArticle
      context:https://schema.org
ScholarlyArticle:
      headline:Zinc finger proteins: watchdogs in muscle development
      description: The specificity of highly differentiated tissues is largely achieved through the action of cell- and stage-restricted transcription factors. The basic events in skeletal muscle development are triggered by a unique family of myogenic basic helix-loop-helix proteins –MyoD, Myf-5, myogenin and MRF-4. Binding sites for these factors are found in the promoter regions of many genes whose expression is restricted to muscle cells, but the tight regulation of gene expression is dependent on the interaction of different factors. In this respect zinc finger proteins seem to play an important role, not only in the establishment of muscle cells but also in the maintenance of muscle function. This review discusses several zinc finger proteins that have been characterized as regulators of muscle development and muscle-specific gene expression.
      datePublished:
      dateModified:
      pageStart:209
      pageEnd:215
      sameAs:https://doi.org/10.1007/s004380050959
      keywords:
         Key words Zinc finger protein
         Muscle development
         E-box
         MRF
         MyoD
         Plant Genetics and Genomics
         Human Genetics
         Microbial Genetics and Genomics
         Animal Genetics and Genomics
         Biochemistry
         general
      image:
      isPartOf:
         name:Molecular and General Genetics MGG
         issn:
            1432-1874
            0026-8925
         volumeNumber:261
         type:
            Periodical
            PublicationVolume
      publisher:
         name:Springer-Verlag
         logo:
            url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
            type:ImageObject
         type:Organization
      author:
            name:A. Krempler
            affiliation:
                  name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
                  address:
                     name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
            name:B. Brenig
            affiliation:
                  name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
                  address:
                     name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
                     type:PostalAddress
                  type:Organization
            type:Person
      isAccessibleForFree:
      hasPart:
         isAccessibleForFree:
         cssSelector:.main-content
         type:WebPageElement
["Periodical","PublicationVolume"]:
      name:Molecular and General Genetics MGG
      issn:
         1432-1874
         0026-8925
      volumeNumber:261
Organization:
      name:Springer-Verlag
      logo:
         url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
         type:ImageObject
      name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
      address:
         name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
         type:PostalAddress
      name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
      address:
         name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
         type:PostalAddress
ImageObject:
      url:https://www.springernature.com/app-sn/public/images/logo-springernature.png
Person:
      name:A. Krempler
      affiliation:
            name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
            address:
               name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
               type:PostalAddress
            type:Organization
      name:B. Brenig
      affiliation:
            name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392
            address:
               name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
               type:PostalAddress
            type:Organization
PostalAddress:
      name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
      name:Institute of Veterinary Medicine, Groner Landstrasse 2 D-37073 Göttingen, Germany e-mail: [email protected] Tel.: +49-551-3383; Fax: +49-551-39-3392, , DE
WebPageElement:
      isAccessibleForFree:
      cssSelector:.main-content

External Links {🔗}(27)

Analytics and Tracking {📊}

Google Tag Manager

Libraries {📚}

Clipboard.js
Prism.js

CDN Services {📦}

Crossref

4.14s.

LINK . SPRINGER . COM {}