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Title:
The HAF2 protein shapes histone acetylation levels of PRR5 and LUX loci in Arabidopsis | Planta
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Main conclusion The histone acetyltransferase HAF2 facilitates H3 acetylation deposition at the PRR5 and LUX promoters to contribute to robust circadian oscillation. The circadian clock ensures synchronization of endogenous rhythmic processes with environmental cycles. Multi-layered regulation underlies precise circadian oscillation, and epigenetic regulation is emerging as a crucial scheme for robust circadian maintenance. Here, we report that HISTONE ACETYLTRANSFERASE OF THE TAFII250 FAMILY 2 (HAF2) is involved in circadian homeostasis. The HAF2 gene is activated at midday, and its temporal expression is shaped by CIRCADIAN CLOCK-ASSOCIATED 1. The midday-activated HAF2 protein stimulates H3 acetylation (H3ac) deposition at the PRR5 and LUX loci, contributing to establishment of the raising phase. These results indicate that epigenetic waves in circadian networks underlie temporal compartmentalization of circadian components and stable maintenance of circadian oscillation.
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circadian, article, pubmed, google, scholar, arabidopsis, clock, cas, histone, plant, haf, acetylation, seo, central, research, lux, regulation, privacy, cookies, protein, prr, lee, cell, content, publish, search, gene, expression, access, mas, physiol, data, information, log, journal, planta, loci, pil, joon, acetyltransferase, oscillation, epigenetic, discover, rhythms, posttranslational, modifications, chromatin, regulate, sci, usa,
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elf4-elf3-lux complex links pil joon seo month download article/chapter light-responsive gene expression seo pj article lee article planta aims full article pdf privacy choices/manage cookies robust circadian oscillation taf1/haf2 interact basic research laboratory national research foundation regulate gene expression proteins circadian rhythms regulate circadian transcription green rm arabidopsis circadian clock plant circadian clock circadian expression profiles histone modifications integrate light signals molecular mechanisms underlying pseudoresponse regulator proteins basic science research robust circadian maintenance haf2 gene european economic area endogenous rhythmic processes rural development administration toc1 transcriptional rhythms conditions privacy policy epigenetic regulation posttranslational regulation electronic supplementary material main content log histone acetyltransferase accepting optional cookies article log arabidopsis cca1/lhy author information authors circadian oscillation article cite circadian clock circadian clock check access instant access journal finder publish histone deacetylases temporal expression
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headline:The HAF2 protein shapes histone acetylation levels of PRR5 and LUX loci in Arabidopsis
description:The histone acetyltransferase HAF2 facilitates H3 acetylation deposition at the PRR5 and LUX promoters to contribute to robust circadian oscillation. The circadian clock ensures synchronization of endogenous rhythmic processes with environmental cycles. Multi-layered regulation underlies precise circadian oscillation, and epigenetic regulation is emerging as a crucial scheme for robust circadian maintenance. Here, we report that HISTONE ACETYLTRANSFERASE OF THE TAFII250 FAMILY 2 (HAF2) is involved in circadian homeostasis. The HAF2 gene is activated at midday, and its temporal expression is shaped by CIRCADIAN CLOCK-ASSOCIATED 1. The midday-activated HAF2 protein stimulates H3 acetylation (H3ac) deposition at the PRR5 and LUX loci, contributing to establishment of the raising phase. These results indicate that epigenetic waves in circadian networks underlie temporal compartmentalization of circadian components and stable maintenance of circadian oscillation.
datePublished:2018-05-22T00:00:00Z
dateModified:2018-05-22T00:00:00Z
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Circadian clock
Epigenetic modification
HAF2
Histone acetylation
Plant Sciences
Agriculture
Ecology
Forestry
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Epigenetic modification
HAF2
Histone acetylation
Plant Sciences
Agriculture
Ecology
Forestry
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Analytics and Tracking {π}
- Google Tag Manager
Libraries {π}
- Clipboard.js
- Prism.js
CDN Services {π¦}
- Crossref